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Pathogenesis of hematological malignancies caused by viral infection

Research Project

Project/Area Number 23591391
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Hematology
Research InstitutionKochi University

Principal Investigator

DAIBATA Masanori  高知大学, 教育研究部医療学系, 教授 (50263976)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords造血器腫瘍 / ウイルス / 癌 / 感染症
Research Abstract

Some virus infections are closely associated with oncogenesis. In 2008, Merkel cell polyomavirus (MCPyV) was reported as the first tumor polyomavirus. The association of MCPyV with chronic lymphocytic leukemia (CLL) has been discussed in the Western world, whereas the prevalence of the virus in CLL cases in Eastern countries has not been investigated. In this study, we determined the prevalence and DNA loads of MCPyV in Japanese CLL cases. We found that MCPyV is present in a subset of Japanese CLL cases, but it is unclear that MCPyV have a direct causal role in Japanese CLL.
Since MCPyV can also infect monocytic cells, we investigated the prevalence of MCPyV in disorders of monocytic lineage. MCPyV DNA was not detected in any of our leukemia samples with the monocytic lineage, suggesting that MCPyV is unlikely to have played a pathogenetic role in the monocytic leukemias of these patients.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (77 results)

All 2014 2013 2012 2011 Other

All Journal Article (28 results) (of which Peer Reviewed: 28 results) Presentation (42 results) Book (4 results) Remarks (3 results)

  • [Journal Article] PCR array analysis of gene expressi on profiles in chronic active Epste in-Barr virus infection2014

    • Author(s)
      Murakami M, Hashida Y, Imajoh M, Ma eda A, Kamioka M, Senda Y, Sato T, Fujieda M, Wakiguchi H, Daibata M
    • Journal Title

      Microbes a nd Infection

      Volume: (掲載決定) Issue: 7 Pages: 581-586

    • DOI

      10.1016/j.micinf.2014.04.004

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Consideration s on the link between Merkel cell p olyomavirus and lung cancer2014

    • Author(s)
      Hashida Y, Daibata M
    • Journal Title

      Lung C ancer Management

      Volume: (掲載決定)

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Phylogenetic analysis of Merkel cell polyomavirus based on full-length LT and VP1 gene sequences derived from neoplastic tumors in Japanese patients.2014

    • Author(s)
      Yumiko Hashida, Masayuki Imajoh, Mikio Kamioka, Ayuko Taniguchi, Naoto Kuroda, Kazuhiko Hayashi, Hideki Nakajima, Shigetoshi Sano, Masanori Daibata.
    • Journal Title

      Journal of General Virology

      Volume: 95 Issue: 1 Pages: 135-141

    • DOI

      10.1099/vir.0.058149-0

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pyothorax-associated lymphoma (PAL) with biclonal Epstein–Barr virus infection: characterization of a novel PAL cell line with unique features.2013

    • Author(s)
      Ayuko Taniguchi, Yumiko Hashida, Yuiko Nemoto, Takahiro Taguchi, Yoshito Iwahara, Masanori Daibata.
    • Journal Title

      Leukemia Research

      Volume: 37 Issue: 11 Pages: 1545-1550

    • DOI

      10.1016/j.leukres.2013.07.033

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Gene expression analysis in Merkel cell polyomavirus-positive non-small cell lung cancer from Japanese patients.2013

    • Author(s)
      Yumiko Hashida, Masayuki Imajoh, Masanori Daibata.
    • Journal Title

      International Journal of Cancer

      Volume: 133 Issue: 12 Pages: 3014-3015

    • DOI

      10.1002/ijc.28305

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Integrated and mutated forms of Merkel cell polyomavirus in non-small cell lung cancer.2013

    • Author(s)
      Yumiko Hashida, Masayuki Imajoh, Masanori Daibata.
    • Journal Title

      British Journal of Cancer

      Volume: 108 Issue: 12 Pages: 2624-2624

    • DOI

      10.1038/bjc.2013.196

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Detection of Merkel cell polyomavirus with a tumour-specific signature in non-small cell lung cancer.2013

    • Author(s)
      Hashida Y, et al.
    • Journal Title

      British Journal of Cancer

      Volume: 108 Issue: 3 Pages: 629-637

    • DOI

      10.1038/bjc.2012.567

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Absence of Merkel cell polyomavirus in monocytic leukemias.2013

    • Author(s)
      Yumiko Hashida, Masayuki Imajoh, Ayuko Taniguchi, Mikio Kamioka, Masanori Daibata.
    • Journal Title

      Acta Haematologica

      Volume: 130 Issue: 3 Pages: 135-137

    • DOI

      10.1159/000347174

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prevalence and viral DNA loads of three novel human polyomaviruses in skin cancers from Japanese patients.2013

    • Author(s)
      Masayuki Imajoh, Yumiko Hashida, Hideki Nakajima, Shigetoshi Sano, Masanori Daibata.
    • Journal Title

      The Journal of Dermatology

      Volume: 40 Issue: 8 Pages: 657-660

    • DOI

      10.1111/1346-8138.12180

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Genotypic characteristics of a Mycobacterium sp. iseolated from yellowtail Seriola quiqueradiata and striped jack Pseudocaranx dentex in Japan2013

    • Author(s)
      Masayuki Imajoh
    • Journal Title

      Microbiology and Immunology

      Volume: 57 Issue: 1 Pages: 13-20

    • DOI

      10.1111/j.1348-0421.2012.00514.x

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Detection of Merkel cell polyomavirus in cervical squamous cell carcinomas and adenocarcinomas from Japanese patients.2012

    • Author(s)
      Imajoh M, et al.
    • Journal Title

      Virology Journal

      Volume: 9 Issue: 1 Pages: 154-154

    • DOI

      10.1186/1743-422x-9-154

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma.2012

    • Author(s)
      Fresquet V, et al.
    • Journal Title

      British Joutnal of Haematology

      Volume: 158 Issue: 6 Pages: 712-726

    • DOI

      10.1111/j.1365-2141.2012.09226.x

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Novel human polyomaviruses, Merkel cell polyomavirus and human polyomavirus 9, in Japanese chronic lymphocytic leukemia cases.2012

    • Author(s)
      Imajoh M, et al.
    • Journal Title

      Journal of Hematology & Oncology

      Volume: 5 Issue: 1 Pages: 25-25

    • DOI

      10.1186/1756-8722-5-25

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Characterization of Epstein-Barr virus (EBV) BZLF1 gene promoter variants and comparison of cellular gene expression profiles in Japanese patients with infectious mononucleosis, chronic active EBV infection, and EBV-associated hemophagocytic lymphohistioc2012

    • Author(s)
      Imajoh M, Hashida Y, Murakami M, Maeda A, Sato T, Fujieda M, Wakiguchi H, Daibata M.
    • Journal Title

      Journal of Medical Virology

      Volume: 84 Issue: 6 Pages: 940-946

    • DOI

      10.1002/jmv.23299

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Inv olvement of KRAS G12A mutation in t he IL-2-independent growth of a hum an T-LGL leukemia cell line, PLT-22012

    • Author(s)
      Mizutani N, Ito H, Hagiwara K, Koba yashi M, Hoshikawa A, Nishida Y, Ta kagi A, Kojima T, Suzuki M, Osawa Y, Ohishi K, Daibata M, Murate T
    • Journal Title

      Nagoya Journal of Medical Science

      Volume: 74, (PMID : 2 3092099) Pages: 261-271

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Promoter methylation of the bone merphorgenetic protein 6 gene in multiple myeloma2012

    • Author(s)
      Yumiko Hashida, Yuiko Nemoto, Masayuki Imajoh, Masanao Murakami, Ayuko Taniguchi, Naoki Komatsu, Akihito Yokoyama, Masanori Daibata
    • Journal Title

      Oncol.Rep.

      Volume: 27 Pages: 825-830

    • DOI

      10.3892/or.2011.1548

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Involvement of KRAS G12A mutation in the IL-2-independent growth of a human T-LGL leukemia cell line, PLT-2.2012

    • Author(s)
      Mizutani N, et al.
    • Journal Title

      Nagoya Journal of Medical Science

      Volume: 74 Pages: 261-271

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Fukushima. Pseudomonas aeruginosa keratitis in mice: effects of topical bacteriophage KPP12 administration.2012

    • Author(s)
      Fukuda K, et al.
    • Journal Title

      PlosOne

      Volume: 7 Issue: 10 Pages: e47742-e47742

    • DOI

      10.1371/journal.pone.0047742

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Complete genome sequences of two Helicobacter pylori bacteriophages isolated from Japanese patients.2012

    • Author(s)
      Uchiyama J, et al.
    • Journal Title

      Journal of Virology

      Volume: 86 Pages: 11400-11401

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Analysis of deoxynucleosides in bacteriophages φEF24C and K and the frequency of a specific restriction site in the genomes of bacteriophage subfamily Spounavirinae.2012

    • Author(s)
      Uchiyama J, et al.
    • Journal Title

      Archives of Virology.

      Volume: 157 Issue: 8 Pages: 1587-1592

    • DOI

      10.1007/s00705-012-1324-9

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Analysis of deoxynucleosides in bacteriophages φEF24C and K and the frequency of a specific restriction site in the genomes of bacteriophage subfamily Spounavirinae.2012

    • Author(s)
      Uchiyama J, Maeda Y, Takemura I, Gamoh K, Matsuzaki S, Daibata M .
    • Journal Title

      Archive of Virology.

      Volume: 未定

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Characterization of Epstein-Barr Virus (EBV) BZLF1 Gene Promoter Variants and Comparison of Cellular Gene Expression Profiles in Japanese Patients with Infectious Mononucleosis, Chronic Active EBV Infection, and EBV-Associated Hemophagocytic Lymphohistiocytosis.2012

    • Author(s)
      Imajoh M, Hashida Y, Murakami M, Maeda A, Sato T, Fujieda M, Wakiguchi H, Daibata M.
    • Journal Title

      Journal of Medical Virology.

      Volume: 未定

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Multiple sites of highly amplified DNA sequences dete cted by molecular cytogenetic analy sis in HS-RMS-2, a new pleomorphic rhabdomyosarcoma cell line2011

    • Author(s)
      Takaoka E, Sonobe H, Akimaru K, Sak amoto S, Shuin T, Daibata M, Taguch i T, Tominaga A
    • Journal Title

      America n Journal of Cancer Research

      Volume: 2 Pages: 141-152

    • URL

      http://www.ajcr.us/ISSN:2156-6976/ajcr0000107

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Presence of Merkel cell polyomavirus in Japanese cutaneous squamous cell carcinoma.2011

    • Author(s)
      Murakami M, Imajoh M, Ikawa T, Nakajima N, Kamioka M, Nemoto Y, Ujihara T, Uchiyama J, Matsuzaki S, Sano S, Daibata M.
    • Journal Title

      J Clin Virol.

      Volume: 50 Issue: 1 Pages: 37-41

    • DOI

      10.1016/j.jcv.2010.09.013

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Characterization of Lytic Enzyme Open Reading Frame 9 (ORF9) Derived from Enterococcus faecalis Bacteriophage φEF24C2011

    • Author(s)
      Jumpei Uchiyama, Iyo Takemura, Ikue Hayashi, Shigenobu Matsuzaki, Miho Satoh, Takako Ujihara, Masanao Murakami, Masayuki Imajoh, Motoyuki Sugai, Masanori Daibata
    • Journal Title

      Applied and Environmental Microbiology

      Volume: 50 Issue: 2 Pages: 37-41

    • DOI

      10.1128/aem.01540-10

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Improved adsorption of an Enterococcus faecalis bacteriophage φEF24C with a spontaneous point mutation2011

    • Author(s)
      Jumpei Uchiyama, Iyo Takemura, Miho Satoh, Shin-ichiro Kato, Takako Ujihara, Kazue Akechi, Shigenobu Matsuzaki, Masanori Daibataa
    • Journal Title

      PLoS ONE

      Volume: 6 Issue: 10 Pages: e26648-e26648

    • DOI

      10.1371/journal.pone.0026648

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Multiple sites of highly amplified DNA sequences detected by molecular cytogenetic analysis in HS-RMS-2, a new pleomorphic rhabdomyosarcoma cell line.2011

    • Author(s)
      Takaoka E, Sonobe H, Akimaru K, Sakamoto S, Shuin T, Daibata M, Taguchi T, Tominaga A.
    • Journal Title

      American Journal of Cancer Research.

      Volume: 2 Pages: 141-152

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Genetic characterization of Pseudomonas aeruginosa bacteriophage KPP102011

    • Author(s)
      Jumpei Uchiyama, Mohammad Rashel, Iyo Takemura, Shin-ichiro Kato, Takako Ujihara, Asako Muraoka, Shigenobu Matsuzaki, Masanori Daibata
    • Journal Title

      Archive of Virology

      Volume: 157 Issue: 4 Pages: 733-738

    • DOI

      10.1007/s00705-011-1210-x

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] 非小細胞肺がんにおけるメルケル細胞ポリオーマウイルスの検出2013

    • Author(s)
      橋田裕美子,大畑雅典,他
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2013-11-10
    • Related Report
      2013 Final Research Report
  • [Presentation] A case of Hodgkin lymphoma associated with c hronic active Epstein-Barr virus in fection2013

    • Author(s)
      谷口亜裕子,大畑雅典,他
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      仙台国際センター、東北大学百周年記念会館川内萩ホール(仙台市)
    • Year and Date
      2013-08-30
    • Related Report
      2013 Final Research Report
  • [Presentation] Development of the BET bromodonain inhibitor OT X0152013

    • Author(s)
      Noel K, Daibata M,他
    • Organizer
      AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
    • Place of Presentation
      Hynes Convent ion Center, Boston, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Development of the BET bromodonain inhibitor OTX015.2013

    • Author(s)
      Kay Noel, Kazunori Iwata, Shinsuke Ooike, Kunio Sugahara, Masanori Daibata, Hideo Nakamura.
    • Organizer
      AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
    • Place of Presentation
      Hynes Convention Center, Boston, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] 本邦におけるメルケル細胞ポリオーマウイルスの分子系統解析2012

    • Author(s)
      今城雅之,大畑雅典,他
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2012-11-15
    • Related Report
      2013 Final Research Report
  • [Presentation] PCR arra y analysis in Japanese chronic acti ve EBV patients2012

    • Author(s)
      Murakami M, Daibata M,他
    • Organizer
      International Cong ress on Oncogenic Herpesviruses and Associated Diseases
    • Place of Presentation
      Sheraton Philad elphia Downtown Hotel, Philadelphia, Pennsylvania, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Identificati on of new target for Nm23-H1 which is an adenomatous polyposis coli-st imulated guanine nucleotide exchang e factor 22012

    • Author(s)
      Murakami M, Daibata M
    • Organizer
      International Congress on Oncogenic Herpesviruses and Asso ciated Diseases
    • Place of Presentation
      Sheraton Philadelphia Downtown Hotel, Philadelphia, Penns ylvania, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] 慢性リンパ性白血病における新規ポリオーマウイルスの検出2012

    • Author(s)
      橋田裕美子,大畑雅典,他
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Related Report
      2013 Final Research Report
  • [Presentation] 慢性活動性E BV感染症のT/B細胞活性についてのPCR array解析2012

    • Author(s)
      村上雅尚,大畑雅典,他
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Related Report
      2013 Final Research Report
  • [Presentation] A case of primary neurolymphomatosis of the lumbar cord nerve root2012

    • Author(s)
      谷口亜裕子,大畑雅典,他
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Related Report
      2013 Final Research Report
  • [Presentation] 慢性リンパ性白血病における新規ポリオーマウイルスの検出2012

    • Author(s)
      橋田裕美子, 大畑雅典, 他
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 慢性活動性EBV感染症のT/B細胞活性についてのPCR array解析2012

    • Author(s)
      村上雅尚, 大畑雅典, 他
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Related Report
      2012 Research-status Report
  • [Presentation] A case of primary neurolymphomatosis of the lumbar cord nerve root.2012

    • Author(s)
      谷口亜裕子, 大畑雅典, 他
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 黄色ブドウ球菌バクテリオファージ尾部吸着タンパク質と細菌側レセプター分子の同定2012

    • Author(s)
      内山淳平, 大畑雅典, 他
    • Organizer
      第65回日本細菌学会中国四国支部総会
    • Place of Presentation
      徳島大学(徳島市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 緑膿菌感染症に対するバクテリオファージ療法系の構築2012

    • Author(s)
      宮田怜奈, 大畑雅典, 他
    • Organizer
      第65回日本細菌学会中国四国支部総会
    • Place of Presentation
      徳島大学(徳島市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 新規緑膿菌バクテリオファージの分離と性状解析2012

    • Author(s)
      山口琴絵, 大畑雅典, 他
    • Organizer
      第65回日本細菌学会中国四国支部総会
    • Place of Presentation
      徳島大学(徳島市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 黄色ブドウ球菌ファージの尾部理癌度タンパク質を利用した細菌検出法の開発2012

    • Author(s)
      内山伊代、内山淳平、松崎茂展、杉浦哲郎、大畑雅典
    • Organizer
      第8回合同地方会(第57回日本臨床検査医学会中国・四国支部総会、第152回に臨床化学会中国支部例会・総、第22回日本臨床化学会四国支部例会・総会)
    • Place of Presentation
      岡山大学(岡山市)
    • Related Report
      2011 Research-status Report
  • [Presentation] 緑膿菌臨床分離株に対するバクテリオファージKPP12の溶菌効果の検討2012

    • Author(s)
      福田憲,石田わか,角環,森田珠恵,内山淳平,松崎茂展,大畑雅典,福島敦樹
    • Organizer
      2012角膜カンファランス(第36回日本角膜学会総会、第28回日本角膜移植学会)
    • Place of Presentation
      ホテルニューオータニ(東京都)
    • Related Report
      2011 Research-status Report
  • [Presentation] バクテリオファージの尾部リガンド分子を利用する細菌同定法2012

    • Author(s)
      松崎茂展、内山淳平、内山(竹村)伊代、大畑雅典
    • Organizer
      国際医薬品原料・中間体展 2012 (CPhIJAPAN2012)(招待講演)
    • Place of Presentation
      東京ビックサイト(東京都)
    • Related Report
      2011 Research-status Report
  • [Presentation] 多発性骨髄腫におけるBMP-6遺伝子メチル化の検討(Promoter methylation of the bone morphogenetic protein-6 gene in mu ltiple myeloma)2011

    • Author(s)
      谷口亜裕子,大畑雅典,他
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2011-10-14
    • Related Report
      2013 Final Research Report
  • [Presentation] KrasG12A mutation is responsible for thecyt okine independent growth of a human LGL leukemia cell line, PLT22011

    • Author(s)
      Mizutani N, Daibata M,他
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2011-10-14
    • Related Report
      2013 Final Research Report
  • [Presentation] 皮膚扁平上皮細胞癌における新規腫瘍ウイルスメルケル細胞ポリオーマウイルスの検出2011

    • Author(s)
      村上雅尚,大畑雅典,他
    • Organizer
      第26回中国四国ウイルス研究会
    • Place of Presentation
      徳島大学青藍会館(徳島市)
    • Year and Date
      2011-06-19
    • Related Report
      2013 Final Research Report
  • [Presentation] Various s ites of highly amplified DNA sequen ces in a pleomorphic type of a new rhambdomyosarcoma cell line, HS-RMS -2, detected by comparative genomic hybridization, chromosome microdis section and PCR analysis2011

    • Author(s)
      Taguchi T, Daibata M,他
    • Organizer
      The 102nd American Association for Cancer Re search Annual Meeting
    • Place of Presentation
      Orange County Convention Center, Orland, Florida, USA
    • Year and Date
      2011-04-02
    • Related Report
      2013 Final Research Report
  • [Presentation] 皮膚扁平上皮細胞癌における新規腫瘍ウイルスメルケル細胞ポリオーマウイルスの検出2011

    • Author(s)
      村上雅尚、今城雅之、中島英貴、佐野栄紀、大畑雅典
    • Organizer
      第26回中国四国ウイルス研究会
    • Place of Presentation
      徳島大学 青藍会館(徳島市)
    • Related Report
      2011 Research-status Report
  • [Presentation] KrasG12A mutation is responsible for thecytokine independent growth of a human LGL leukemia cell line, PLT2.2011

    • Author(s)
      Mizutani N, Ito H, Hagiwara K, Murakami M, Kobayashi M, Hoshikawa A, Sobue S, Takagi A, Kojima T, Suzuki M, Ohnishi K, Naoe T, Daibata M, Murate T.
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2011 Research-status Report
  • [Presentation] Improved adsorption of Enterococcus faecalis bacteriophage φEF24C caused by a point mutation in a tail fiber gene.2011

    • Author(s)
      Uchiyama J, Takemura I, Satoh M, Kato S, Ujihara T, Akechi K, Matsuzaki, S, Daibata M.
    • Organizer
      International Union of Microbiological Societies (IUMS), XV International Congress of Virology
    • Place of Presentation
      Sapporo Convention Center, Sapporo, Japan
    • Related Report
      2011 Research-status Report
  • [Presentation] Identification of a tail adsorption protein by comparative genomic analysis of Staphylococcus aureus bacteriophages S13’ and S24-1.2011

    • Author(s)
      Takemura I, Uchiyama J, Satoh M, Kato S, Ujihara T, Matsuzaki S, Daibata M.
    • Organizer
      International Union of Microbiological Societies (IUMS), XV International Congress of Virology
    • Place of Presentation
      Sapporo Convention Center, Sapporo, Japan
    • Related Report
      2011 Research-status Report
  • [Presentation] Various sites of highly amplified DNA sequences in a pleomorphic type of a new rhambdomyosarcoma cell line, HS-RMS-2, detected by comparative genomic hybridization, chromosome microdissection and PCR analysis.2011

    • Author(s)
      Taguchi T, Takaoka E, Sonobe H, Akimaru K, Sakamoto S, Shuin T, Daibata M, Tominaga A.
    • Organizer
      The 102nd American Association for Cancer Research Annual Meeting.
    • Place of Presentation
      Orange County Convention Center, Orland, Florida, USA
    • Related Report
      2011 Research-status Report
  • [Presentation] バクテリオファージによる緑膿菌角膜炎の抑制効果2011

    • Author(s)
      福田憲、石田わか、角環、内山淳平、松崎茂展、大畑雅典、福島敦樹
    • Organizer
      第48回日本眼感染症学会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Related Report
      2011 Research-status Report
  • [Presentation] 感染効率が改善された腸球菌バクテリオファージφEF24C変異体の解析2011

    • Author(s)
      内山淳平,竹村伊代,佐藤美帆,加藤伸一郎,氏原隆子,明智和愛,松崎茂展,大畑雅典
    • Organizer
      第5回細菌学・若手コロッセウム
    • Place of Presentation
      高知大学(南国市)
    • Related Report
      2011 Research-status Report
  • [Presentation] 黄色ブドウ球菌バクテリオファージS13’およびS24-1ゲノム比較による尾部吸着タンパク質の同定と解析2011

    • Author(s)
      内山淳平、竹村伊代、佐藤美帆、加藤伸一郎、氏原隆子、松崎茂展、大畑雅典
    • Organizer
      第56回日本ブドウ球菌研究会
    • Place of Presentation
      高知市総合あんしんセンター(高知市)
    • Related Report
      2011 Research-status Report
  • [Presentation] 多発性骨髄腫におけるBMP-6遺伝子メチル化の検討(Promoter methylation of the bone morphogenetic protein-6 gene in multiple myeloma)2011

    • Author(s)
      谷口亜裕子、根本由以子、小松直樹、横山彰仁、大畑雅典
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2011 Research-status Report
  • [Presentation] 遺伝的背景を維持したLewisラットおよびBrown-Norwayラット骨髄由来の樹状細胞株の樹立2011

    • Author(s)
      森沢啓子、小味秀行、苫谷文子、近藤基樹、都留忍、戸高寛、樋口琢磨、尾畑恩秀、坂本修士、津田雅之、村上雅尚、大畑雅典、谷口武利
    • Organizer
      日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2011 Research-status Report
  • [Presentation] 緑膿菌ファージKPP10のゲノムDNA解析2011

    • Author(s)
      内山淳平、竹村伊代、氏原隆子、邑岡麻子、松崎茂展、大畑雅典
    • Organizer
      第64回日本細菌学会中国・四国支部総会
    • Place of Presentation
      、岡山大学津島キャンパス(岡山市)
    • Related Report
      2011 Research-status Report
  • [Presentation] A case of Hodgkin lymphoma associated with chronic active Epstein-Barr virus infection.

    • Author(s)
      谷口亜裕子、池添隆之、砥谷和人、佐藤哲也、大畑雅典、横山彰仁
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      仙台国際センター、東北大学百周年記念会館川内萩ホール(仙台市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 非小細胞肺がんにおけるメルケル細胞ポリーマウイルスの検出

    • Author(s)
      橋田裕美子、今城雅之、村上雅尚、根本由以子、上岡樹生、谷口亜裕子、田口尚弘、大畑雅典
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 本邦におけるメルケル細胞ポリオーマウイルスの分子系統解析

    • Author(s)
      今城雅之, 大畑雅典, 他
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 難治性黄色ブドウ球菌感染症に対するバクテリオファージ療法の開発:治療用ファージバンクの構築

    • Author(s)
      内山淳平, 大畑雅典, 他
    • Organizer
      第86回日本感染症学会総会・学術講演会
    • Place of Presentation
      長崎ブリックホール(長崎市)
    • Related Report
      2012 Research-status Report
  • [Presentation] ファージリガンド分子を利用した最近検査法の開発

    • Author(s)
      内山淳平, 大畑雅典, 他
    • Organizer
      第86回日本感染症学会総会・学術講演会
    • Place of Presentation
      長崎ブリックホール(長崎市)
    • Related Report
      2012 Research-status Report
  • [Presentation] ピロリ菌バクテリオファージの分離・解析

    • Author(s)
      内山淳平, 大畑雅典, 他
    • Organizer
      第4回ファージ研究会
    • Place of Presentation
      群馬大学(前橋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Improved adsorption of Enterococcus faecalis bacteriophage EF24C caused by a point mutation in a tail fiber gene

    • Author(s)
      内山淳平, 大畑雅典, 他
    • Organizer
      第4回ファージ研究会
    • Place of Presentation
      群馬大学(前橋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] ピロリ菌バクテリオファージ(ファージ)KHP30の形態とゲノム解析

    • Author(s)
      内山淳平, 大畑雅典, 他
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ国際会議場(千葉市)
    • Related Report
      2012 Research-status Report
  • [Book] 感染症と発癌:リンパ腫関連ウイルスとリンパ腫,臨床検査2013

    • Author(s)
      村上雅尚、大畑雅典
    • Publisher
      医学書院
    • Related Report
      2013 Final Research Report
  • [Book] 悪性リンパ腫(膿胸関連リンパ腫pyothorax-associated lymphoma : PAL)2013

    • Author(s)
      大畑雅典
    • Publisher
      医学書院
    • Related Report
      2013 Final Research Report
  • [Book] 感染症と発癌:リンパ腫関連ウイルスとリンパ腫、臨床検査2013

    • Author(s)
      村上雅尚、大畑雅典
    • Total Pages
      7
    • Publisher
      医学書院
    • Related Report
      2013 Annual Research Report
  • [Book] 悪性リンパ腫(膿胸関連リンパ腫 pyothorax-associated lymphoma: PAL)2013

    • Author(s)
      大畑雅典
    • Total Pages
      2
    • Publisher
      医学書院
    • Related Report
      2013 Annual Research Report
  • [Remarks] ホームページ等, 高知大学医学部

    • URL

      http://www.kochi-ms.ac.jp/

    • Related Report
      2013 Final Research Report
  • [Remarks] 高知大学医学部

    • URL

      http://www.kochi-ms.ac.jp/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 高知大学医学部

    • URL

      http://www.kochi-ms.ac.jp/

    • Related Report
      2012 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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