Hematopoietic Stem Cell Transplantation

• Project/Area Number: 23591423
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Hematology
• Research Institution: Osaka City University
• Principal Investigator: HINO Masayuki 大阪市立大学, 医学(系)研究科(研究院), 教授 (50244637)
• Co-Investigator(Kenkyū-buntansha): NAKAMAE Hirohisa 大阪市立大学, 大学院医学研究科, 准教授 (30364003)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 同種造血幹細胞移植 / HLA半合致移植 / GVHD / 移植後シクロホスファミド / バイオマーカー / 消化管GVHD / ステロイド動注 / ベクロメタゾン / 移植後大量シクロホスファミド投与 / 移植片対宿主病 / 非寛解造血器悪性腫瘍 / 類洞閉塞症 / 閉塞性細気管支炎 / フェリチン / 移植後血球貪食症候群

Research Abstract

A myeloablative regimen involved high-dose TBI impaired cardiac function. A high s-ferritin level before HCT might be associated with the development of LVH in the chronic phase of HCT. A high s-ferritin level after HCT might be a prognostic factor. Eosinophilia after allo-HCT was associated with better OS and a lower relapse rate. Dysregulated balance between Th1 and Th2 cytokines might play an important role in the incidence of HPS after allo-HCT. Prospective pilot study of HLA haplo-identical allogeneic PBSCT using cyclophosphamide post-transplantation for patients with a poor-prognosis or refractory leukemia and MDS showed that except for one patient who died due to disease progression, full donor T-cell chimerism was achieved at day 30 in all patients, 53% of patients developed grade II-III acute GVHD, the cumulative incidence of TRM at one year was 13%, and the OS at one year of all patients, patients in remission and those with active disease were 43%, 75% and 31%, respectively.

Research Products

• [Journal Article] Feasibility of umbilical cord blood transplantation with a myeloablative, reduced toxicity-conditioning regimen. (2014)
  • Author(s): Nishimoto M, Nakamae H, Nakamae M, Hirose A, Hagihara K, Koh H, Nakane T, Terada Y, Hino M.
  • Journal Title: Bone Marrow Transplant Volume: in press Issue: 7 Pages: 980-981
  • DOI: 10.1038/bmt.2014.60
  • Peer Reviewed
• [Journal Article] PBSC collection from family donors in Japan : a prospective survey (2014)
  • Author(s): Kodera Y, Yamamoto K, Harada M, Morishima Y, Dohy H, Asano S, Ikeda Y, Nakahata T, Imamura M, Kawa K, Kato S, Tanimoto M, Kanda Y, Tanosaki R, Shiobara S, Kim SW, Nagafuji K, Hino M, Miyamura K, Suzuki R, Hamajima N, Fukushima M, Tamakoshi A
  • Journal Title: Bone Marrow Transplant Volume: 49 Issue: 2 Pages: 195-200
  • DOI: 10.1038/bmt.2013.147
  • Peer Reviewed
• [Journal Article] Maintenance of complete remission after allogeneic stem cell transplantation in leukemia patients treated with Wilms tumor 1 peptide vaccine (2013)
  • Author(s): Maeda T, Hosen N, Fukushima K, Tsuboi A, Morimoto S, Matsui T, Sata H, Fujita J, Hasegawa K, Nishida S, Nakata J, Nakae Y, Takashima S, Nakajima H, Fujiki F, Tatsumi N, Kondo T, Hino M, Oji Y, Oka Y, Kanakura Y, Kumanogoh A, Sugiyama H
  • Journal Title: Blood Cancer J Volume: 3 Issue: 8 Pages: e130-e130
  • DOI: 10.1038/bcj.2013.29
  • Peer Reviewed
• [Journal Article] Prognostic factors and outcomes of unrelated bone marrow transplantation for Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) pre-treated with tyrosine kinase inhibitors (2013)
  • Author(s): Yoshimura T, Nakane T, Hirose A, Koh H, Nakamae M, Aimoto M, Nishimoto M, Hayashi Y, Terada Y, Nakamae H, Hino M
  • Journal Title: Osaka City Med J Volume: 59 Pages: 9-21
  • NAID: 120006493290
  • Peer Reviewed
• [Journal Article] Clinical factors predicting the response of acute graft-versus-host disease to corticosteroid therapy: an analysis from the GVHD working group of the Japan Society for Hematopoietic Cell Transplantation. (2013)
  • Author(s): Murata M, Nakasone H, Kanda J, Nakane T, Furukawa T, Fukuda T, Mori T, Taniguchi S, Eto T, Ohashi K, Hino M, Inoue M, Ogawa H, Atsuta Y, Nagamura-Inoue T, Yabe H, Morishima Y, Sakamaki H, Suzuki R.
  • Journal Title: Biology of Blood and Marrow Transplantation Volume: 19 Issue: 8 Pages: 1183-1189
  • DOI: 10.1016/j.bbmt.2013.05.003
  • Peer Reviewed
• [Journal Article] Use of per rectal portal scintigraphy to detect portal hypertension in sinusoidal obstructive syndrome following unrelated cord blood transplantation (2013)
  • Author(s): Okamura H, Hayashi Y, Nakamae H, Shiomi S, Nishimoto M, Koh H, Nakane T, Hino M
  • Journal Title: Acta Haematol Volume: 130 Issue: 2 Pages: 83-86
  • DOI: 10.1159/000346438
  • Peer Reviewed
• [Journal Article] Risk factors affecting cardiac left-ventricular hypertrophy and systolic and diastolic function in the chronic phase of allogeneic hematopoietic cell transplantation. (2013)
  • Author(s): Nishimoto M, Nakamae H, Koh H, Nakane T, Nakamae M, Hirose A, Hagihara K, Nakao Y, Terada Y, Ohsawa M, Hino M.
  • Journal Title: Bone Marrow Transplant Volume: 84 Issue: 4 Pages: 581-586
  • DOI: 10.1038/bmt.2012.179
  • Peer Reviewed
• [Journal Article] Comparison of outcomes between autologous and allogeneic hematopoietic stem cell transplantation for peripheral T-cell lymphomas with central review of pathology. (2013)
  • Author(s): Kim SW, Yoon SS, Suzuki R, Matsuno Y, Yi HG, Yoshida T, Imamura M, Wake A, Miura K, Hino M, Ishikawa T, Kim JS, Maeda Y, Lee JJ, Kang HJ, Lee HS, Lee JH, Izutsu K, Fukuda T, Kim CW, Yoshino T, Ohshima K, Nakamura S, Nagafuji K, Suzumiya J, Harada M, Kim CS.
  • Journal Title: Leukemia. Volume: 27 Issue: 6 Pages: 1394-1397
  • DOI: 10.1038/leu.2012.321
  • Peer Reviewed
• [Journal Article] Prognostic factors and outcomes of unrelated bone marrow transplantation for Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) pre-treated with tyrosine kinase inhibitors. (2013)
  • Author(s): Yoshimura T, Nakane T, Hirose A, Koh H, Nakamae M, Aimoto M, Nishimoto M, Hayashi Y, Terada Y, Nakamae H, Hino M.
  • Journal Title: Osaka City Med J Volume: 59 Pages: 9-21
  • NAID: 120006493290
  • Peer Reviewed
• [Journal Article] Comparison of outcomes between autologous and allogeneic hematopoietic stem cell transplantation for peripheral T-cell lymphomas with central review of pathology. (2013)
  • Author(s): Kim SW, Yoon SS, Suzuki R, Matsuno Y, Yi HG, Yoshida T, Imamura M, Wake A, Miura K, Hino M, Ishikawa T, Kim JS, Maeda Y, Lee JJ, Kang HJ, Lee HS, Lee JH, Izutsu K, Fukuda T, Kim CW, Yoshino T, Ohshima K, Nakamura S, Nagafuji K, Suzumiya J, Harada M, Kim CS.
  • Journal Title: Leukemia. Volume: 27 Pages: 1394-1397
  • Peer Reviewed
• [Journal Article] Use of per Rectal Portal Scintigraphy to Detect Portal Hypertension in Sinusoidal Obstructive Syndrome following Unrelated Cord Blood Transplantation. (2013)
  • Author(s): Okamura H, Hayashi Y, Nakamae H, Shiomi S, Nishimoto M, Koh H, Nakane T, Hino M.
  • Journal Title: Acta Haematol Volume: 130 Pages: 83-86
  • Peer Reviewed
• [Journal Article] Dasatinib Maintenance Therapy after Allogeneic Hematopoietic Stem Cell Transplantation for an Isolated Central Nervous System Blast Crisis in Chronic Myelogenous Leukemia. (2013)
  • Author(s): Nishimoto M, Nakamae H, Koh KR, Kosaka S, Matsumoto K, Morita K, Koh H, Nakane T, Ohsawa M, Hino M
  • Journal Title: Acta Haematol Volume: 130 Pages: 111-114
  • Peer Reviewed
• [Journal Article] Eosinophilia, regardless of degree, is related to better outcomes after allogeneic hematopoietic stem cell transplantation (2012)
  • Author(s): Nakane T, Nakamae H, Hirose A, Nakamae M, Koh H, Hayashi Y, Nishimoto M, Umemoto Y, Yoshimura T, Bingo M, Okamura H, Yoshida M, Ichihara H, Aimoto M, Terada Y, Nakao Y, Ohsawa M, Hino M
  • Journal Title: Intern Med Volume: 51 Pages: 851-858
  • NAID: 130002061865
  • Peer Reviewed
• [Journal Article] Serum Cytokine Profiles in Hemophagocytic Syndrome following Allogeneic Hematopoietic Stem Cell Transplantation (2012)
  • Author(s): Koh H, Nakane T, Sakamoto E, Katayama T, Nakamae H, Ohsawa M, Hino M
  • Journal Title: Acta Haematol Volume: 127 Issue: 3 Pages: 182-185
  • DOI: 10.1159/000335536
  • Peer Reviewed
• [Journal Article] 非血縁者間末梢血幹細胞採取 (2012)
  • Author(s): 日野雅之
  • Journal Title: 日本アフェレーシス学会雑誌 Pages: 209-215
• [Journal Article] Fatal BK virus pneumonia following stem cell transplantation. (2012)
  • Author(s): Akazawa Y, Terada Y, Yamane T, Tanaka S, Aimoto M, Koh H, Nakane T, Koh KR, Nakamae H, Ohsawa M, Wakasa K, Hino M.
  • Journal Title: Transpl Infect Dis Volume: 14 Issue: 6
  • DOI: 10.1111/tid.12011
  • Peer Reviewed
• [Journal Article] Prolonged sinus tachycardia caused by human herpesvirus 6 (HHV6) encephalomyelitis after allogeneic bone marrow transplantation. (2012)
  • Author(s): Nishimoto M, Nakamae H, Hayashi Y, Koh H, Nakane T, Yoshida M, Bingo M, Okamura H, Aimoto M, Nanno S, Yoshimura T, Inaba A, Hagihara K, Nakamae M, Hirose A, Nakao Y, Terada Y, Hino M
  • Journal Title: Intern Med Volume: 51 Pages: 1265-1267
  • NAID: 130002062445
  • Peer Reviewed
• [Journal Article] Eosinophilia, regardless of degree, is related to better outcomes after allogeneic hematopoietic stem cell transplantation. (2012)
  • Author(s): Nakane T, Nakamae H, Hirose A, Nakamae M, Koh H, Hayashi Y, Nishimoto M, Umemoto Y, Yoshimura T, Bingo M, Okamura H, Yoshida M, Ichihara H, Aimoto M, Terada Y, Nakao Y, Ohsawa M, Hino M.
  • Journal Title: Intern Med Volume: 51 Pages: 851-858
  • NAID: 130002061865
  • Peer Reviewed
• [Journal Article] Serum Cytokine Profiles in Hemophagocytic Syndrome following Allogeneic Hematopoietic Stem Cell Transplantation. (2012)
  • Author(s): Koh H, Nakane T, Sakamoto E, Katayama T, Nakamae H, Ohsawa M, Hino M
  • Journal Title: Acta Haematol Volume: 18 Pages: 182-185
  • Peer Reviewed
• [Journal Article] Immunoglobulin prophylaxis against cytomegalovirus infection in patients at high risk of infection following allogeneic hemato poietic cell transplantation (2011)
  • Author(s): Ichihara H, Nakamae H, Hirose A, Nakane T, Koh H, Hayashi Y, Nishimoto M, Nakamae M, Yoshida M, Bingo M, Okamura H, Aimoto M, Manabe M, Hagihara K, Terada Y, Nakao Y, Hino M
  • Journal Title: Transplant Proc Volume: 43 Issue: 10 Pages: 3927-3932
  • DOI: 10.1016/j.transproceed.2011.08.104
  • Peer Reviewed
• [Journal Article] Immunoglobulin prophylaxis against cytomegalovirus infection in patients at high risk of infection following allogeneic hematopoietic cell transplantation. (2011)
  • Author(s): Ichihara H, Nakamae H, Hirose A, Nakane T, Koh H, Hayashi Y, Nishimoto M, Nakamae M, Yoshida M, Bingo M, Okamura H, Aimoto M, Manabe M, Hagihara K, Terada Y, Nakao Y, Hino M.
  • Journal Title: Transplant Proc Volume: 43 Pages: 3927-3932
  • Peer Reviewed
• [Journal Article] Factors that contribute to long-term survival in patients with leukemia not in remission at allogeneic hematopoietic cell transplantation. (2011)
  • Author(s): Koh H, Nakamae H, Hagihara K, Nakane T, Manabe M, Hayashi Y, Nishimoto M, Umemoto Y, Nakamae M, Hirose A, Inoue E, Inoue A, Yoshida M, Bingo M, Okamura H, Hino M, et al
  • Journal Title: J Exp Clin Cancer ResHematol Volume: 30 Pages: 36-36
  • Peer Reviewed
• [Journal Article] Reduced-intensity conditioning by fludarabine/busulfan without additional irradiation or T-cell depletion leads to low non-relapse mortality in unrelated bone marrow transplantation. (2011)
  • Author(s): Nakane T, Nakamae H, Koh H, Nakamae M, Hayashi Y, Nishimoto M, Yoshimura T, Inoue E, Inoue A, Aimoto R, Aimoto M, Terada Y, Koh KR, Yamane T, Hino M
  • Journal Title: Int J Hematol Volume: 93 Pages: 509-516
  • NAID: 10029534640
  • Peer Reviewed
• [Presentation] Promising outcomes from intra-arterial steroid infusions in patients with treatment-resistant acute gastrointestinal graft-versus-host disease (2014)
  • Author(s): Nishimoto M, Koh H, Nakamae H, Hirose A, Nakamae M, Nakane T, Hayashi Y, Okamura H, Yoshimura Y, Koh S, Nanno S, Hamamoto S, Yamamoto A, Sakai Y, Nishida N, Matsuoka T, Miki Y, Hino M
  • Organizer: 40th Annual Meeting of the European Society for Blood and Marrow Transplantation
  • Place of Presentation: Milan, Italy
• [Presentation] 予後不良、治療抵抗性急性白血病、MDSに対する移植後CY大量療法によるHLA半合致末梢血幹細胞移植の単施設前向きpilot研究 (2014)
  • Author(s): 中前博久、康秀男、西本光孝、中嶋康博、南野智、吉村卓朗、康史朗、岡村浩史、幕内陽介、久野雅智、中根孝彦、中前美佳、廣瀬朝生、日野雅之
  • Organizer: 第36回日本造血細胞移植学会総会
  • Place of Presentation: 沖縄、沖縄コンベンションセンター
• [Presentation] 患者とドナーのKIR遺伝子型が移植後CY大量療法を用いたハプロ移植後の再発に及ぼす影響 (2014)
  • Author(s): 康秀男、中前博久、幕内陽介、久野雅智、長崎譲慈、康史朗、岡村浩史、吉村卓朗、南野智、西本光孝、井上有希子、廣瀬朝生、中前美佳、中嶋康博、萩原潔通、寺田芳樹、中根孝彦、日野雅之
  • Organizer: 第36回日本造血細胞移植学会総会
  • Place of Presentation: 沖縄、沖縄コンベンションセンター
• [Presentation] HLA一致血縁または7-8/8HLA一致非血縁ドナーからの同種造血幹細胞移植におけるMMFおよびカルシニューリン阻害剤を用いたGVHD予防の有用性:多施設共同第2相臨床試験 (2014)
  • Author(s): 中根孝彦、中前博久、黒澤彩子、岡村篤夫、日高道弘、山下卓也、河野彰夫、斉藤健、青山泰孝、畑中一生、片山義雄、薬師神公和、松井利充、高見昭良、山口拓洋、日野雅之、福田隆浩
  • Organizer: 第36回日本造血細胞移植学会総会
  • Place of Presentation: 沖縄、沖縄コンベンションセンター
• [Presentation] Voriconazole vs. itraconazole for antifungal prophylaxis in patients with GVHD : A prospective randomized trial (2014)
  • Author(s): Hayashi Y, Kanda Y, Nakamae H, Kanamori H, Ohashi K, Hidaka M, Yano S, Hatanaka K, Kono A, Moriuchi Y, Ago H, Yamashita T, Takata T, Yoshida M, Hino M, Yamaguchi T, Fukuda T
  • Organizer: BMT tandem meeting
  • Place of Presentation: Dallas, Texas,USA
• [Presentation] Promising outcomes from intra-arterial steroid infusions in patients with treatment-resistant acute gastrointestinal graft-versus-host disease (2014)
  • Author(s): Nishimoto M, Koh H, Nakamae H, Hirose A, Nakamae M, Nakane T, Hayash Y, Okamura H, Yoshimura T, Koh S, Nanno S, Hamamoto S, Yamamoto A, Sakai Y, Nishida N, Matsuoka T, Miki Y, Hino M
  • Organizer: 40th Annual Meeting of the European Society for Blood and Marrow Transplantation
  • Place of Presentation: Milan, Italy, MiCo, Piazzale Carlo Magno
• [Presentation] Voriconazole vs. itraconazole for antifungal prophylaxis in patients with GVHD:A prospective randomized trial (2014)
  • Author(s): Hayashi Y, Kanda Y, Nakamae H, Kanamori H, Ohashi K, Hidaka M, Yano S, Hatanaka K, Kono A, Moriuchi Y, Ago H, Yamashita T, Takata T, Yoshida M, Hino M, Yamaguchi T, Fukuda T
  • Organizer: 2014 BMT tandem meeting
  • Place of Presentation: Dallas, Texas, USA, Gaylord Texan Convention Center
• [Presentation] HLA一致血縁または7-8/8HLA一致非血縁ドナーからの同種造血幹細胞移植におけるMMFおよびカルシニューリン阻害剤を用いたGVHD予防の有用性：多施設共同第2相臨床試験 (2014)
  • Author(s): 中根孝彦、中前博久、黒澤彩子、岡村篤夫、日高道弘、山下卓也、河野彰夫、斉藤 健、青山泰孝、畑中一生、片山義雄、薬師神公和、松井利充、高見昭良、山口拓洋、日野雅之、福田隆浩
  • Organizer: 第36回日本造血細胞移植学会総会
  • Place of Presentation: 沖縄、沖縄コンベンションセンター
• [Presentation] HLA Haplo-Identical Peripheral Blood Stem Cell Transplantation Using High-Dose Cyclophosphamide Post-Transplantation For Poor Prognosis Or Refractory Acute Leukemia and Myelodysplastic Syndrome : A Prospective Pilot Study At a Single Center (2013)
  • Author(s): Nakamae H, Koh H, Nishimoto M, Nakashima Y, Nanno S, Yoshimura T, Koh S, Okamura H, Nagasaki J, Nakane T, Nakamae M, Hirose A, Hino M
  • Organizer: 55th American Society of Hematology
  • Place of Presentation: New Orleans, USA
• [Presentation] Gvhd Prophylaxis With Mycophenolate Mofetil and Calcineurin Inhibitor In Allogeneic Hematopoietic Cell Transplantation From HLA-Matched Siblings Or 7–8/8 HLA-Matched Unrelated Volunteer Donors : A Japanese, Multicenter, Phase II Trial (2013)
  • Author(s): Nakane T, Nakamae H, Kurosawa S, Okamura A, Hidaka M, Yamashita T, Kohno A, Saito T, Aoyama Y, Hatanaka K, Katayama Y, Yakushijin K, Matsui T, Takami A, Yamaguchi T, Hino M, Fukuda T
  • Organizer: 55th American Society of Hematology
  • Place of Presentation: New Orleans, USA
• [Presentation] Risk factor hor hemophagositic syndrome following allogeneic hematopoietic cell transplamtaion (2013)
  • Author(s): Nanno S, Koh H, Sakabe M, Nagasaki J, Okamura H, Koh S, Yoshimura T, Inaba A, Aimoto M, Nishimoto M, Hirose A, Nakamae M, Nakashima Y, Hagihara K, Nakao Y, Nakane T, Terada Y, Nakamae H, Hino M
  • Organizer: 第75回日本血液学会総会
  • Place of Presentation: ロイトン札幌, 札幌
• [Presentation] Voriconazole vs itraconazole for antifungal prophylaxis in patients with GVHD : A randomized trial (2013)
  • Author(s): Hayashi Y, Kanda Y, Nakamae H, Kanamori H, Ohashi K, Hidaka M, Yano S, Hatanaka K, Kohno A, Moriuchi Y, Ago H, Yamashita T, Hino M, Yamaguchi T, Fukuda T
  • Organizer: 第75回日本血液学会
  • Place of Presentation: ロイトン札幌, 札幌
• [Presentation] 東大医科研方式導入後のAraC/CY/TBIを前処置に用いた非血縁臍帯血移植成績の変化 (2013)
  • Author(s): 西本光孝、中前博久、廣瀬朝生、梅本由香里、中前美佳、康秀男、中根孝彦、日野雅之
  • Organizer: 第35回日本造血細胞移植学会
  • Place of Presentation: 石川県立音楽堂, 金沢
• [Presentation] 当院におけるステロイド抵抗性・依存性急性GVHDに対する少量サイモグロブリン(ATG)治療成績 (2013)
  • Author(s): 西本光孝、中前博久、廣瀬朝生、梅本由香里、中前美佳、康秀男、中根孝彦、日野雅之
  • Organizer: 第35回日本造血細胞移植学会
  • Place of Presentation: 石川県立音楽堂, 金沢
• [Presentation] HLA Haplo-Identical Peripheral Blood Stem Cell Transplantation Using High-Dose Cyclophosphamide Post-Transplantation For Poor Prognosis Or Refractory Acute Leukemia and Myelodysplastic Syndrome: A Prospective Pilot Study At a Single Center (2013)
  • Author(s): Nakamae H, Koh H, Nishimoto M, Nakashima Y, Nanno S, Yoshimura T, Koh S, Okamura H, Nagasaki J, Nakane T, Nakamae M, Hirose A, Hino M
  • Organizer: 55th American Society of Hematology
  • Place of Presentation: New Orleans, USA, Moscone Center
• [Presentation] Gvhd Prophylaxis With Mycophenolate Mofetil and Calcineurin Inhibitor In Allogeneic Hematopoietic Cell Transplantation From HLA-Matched Siblings Or 7-8/8 HLA-Matched Unrelated Volunteer Donors: A Japanese, Multicenter, Phase II Trial (2013)
  • Author(s): Nakane T, Nakamae H, Kurosawa S, Okamura A, Hidaka M, Yamashita T, Kohno A, Saito T, Aoyama Y, Hatanaka K, Katayama Y, Yakushijin K, Matsui T, Takami A, Yamaguchi T, Hino M, FukudaT
  • Organizer: 55th American Society of Hematology
  • Place of Presentation: New Orleans, USA, Moscone Center
• [Presentation] Risk factor hor hemophagositic syndrome following allogeneic hematopoietic cell transplamtaion (2013)
  • Author(s): Nanno S, Koh H, Sakabe M, Nagasaki J, Okamura H, Koh S, Yoshimura T, Inaba A, Aimoto M, Nishimoto M, Hirose A, Nakamae M, Nakashima Y, Hagihara K, Nakao Y, Nakane T, Terada Y, Nakamae H, Hino M
  • Organizer: 第75回日本血液学会総会
  • Place of Presentation: 札幌、ロイトン札幌
• [Presentation] Voriconazole vs itraconazole for antifungal prophylaxis in patients with GVHD: A randomized trial (2013)
  • Author(s): Hayashi Y, Kanda Y, Nakamae H, Kanamori H, Ohashi K, Hidaka M, Yano S, Hatanaka K, Kohno A, Moriuchi Y, Ago H, Yamashita T, Hino M, Yamaguchi T, Fukuda T
  • Organizer: 第75回日本血液学会総会
  • Place of Presentation: 札幌、ロイトン札幌
• [Presentation] 東大医科研方式導入後のAraC/CY/TBIを前処置に用いた非血縁臍帯血移植成績の変化. (2013)
  • Author(s): 西本光孝、中前博久、廣瀬朝生、梅本由香里、中前美佳、康 秀男、中根孝彦、日野雅之
  • Organizer: 第35回日本造血細胞移植学会総会
  • Place of Presentation: 金沢
• [Presentation] 当院におけるステロイド抵抗性・依存性急性GVHDに対する少量サイモグロブリン（ATG）治療成績 (2013)
  • Author(s): 西本光孝、中前博久、廣瀬朝生、梅本由香里、中前美佳、康 秀男、中根孝彦、日野雅之
  • Organizer: 第35回日本造血細胞移植学会総会
  • Place of Presentation: 金沢
• [Presentation] 同種造血幹細胞移植後慢性期における心機能障害リスク因子の評価 (2012)
  • Author(s): 西本光孝、中前博久、中根孝彦、康秀男、林良樹、中前美佳、吉田全宏、備後真登、岡村浩史、相本瑞樹、間部賢寛、吉村卓朗、稲葉晃子、南野智、廣瀬朝生、萩原潔通、中尾吉孝、寺田芳樹、日野雅之
  • Organizer: 第34回日本造血細胞移植学会
  • Place of Presentation: 大阪国際会議場, 大阪
• [Presentation] 同種造血幹細胞移植後好酸球増多およびその程度が移植予後へ与える影響についての検討 (2012)
  • Author(s): 中根孝彦、中前博久、廣瀬朝生、康秀男、中前美佳、林良樹、西本光孝、吉田全宏、備後真登、岡村浩史、梅本由香里、稲葉晃子、吉村卓朗、市原弘善、南野智、萩原潔通、寺田芳樹、日野雅之
  • Organizer: 第34回日本造血細胞移植学会
  • Place of Presentation: 大阪国際会議場, 大阪
• [Presentation] 非血縁者末梢血幹細胞採取における施設内CTCとバンクコーディネーターの協働の試み (2012)
  • Author(s): 梅本由香里、中前美佳、廣瀬朝生、樋口智子、片山貴子、津田泉、中根孝彦、日野雅之
  • Organizer: 第34回日本造血細胞移植学会
  • Place of Presentation: 大阪国際会議場, 大阪
• [Presentation] 同種造血幹細胞移植前および、移植後の血清フェリチン値が予後に与える影響の包括的検討. (2012)
  • Author(s): 中前美佳、中前博久、康 秀男、中根孝彦、廣瀬朝生、中嶋康博、日野雅之
  • Organizer: 第59回日本臨床検査医学会
  • Place of Presentation: 京都
• [Presentation] 再発ハイリスク同種造血幹細胞移植後患者に対するWT1ペプチドワクチン第１相臨床試験 (2012)
  • Author(s): 保仙直毅、前田哲生、福島健太郎、森本創世子、中田 潤、中江吉希、西田純幸、坪井昭博、近藤忠一、門脇則光、日野雅之、尾路祐介、岡 芳弘、熊ノ郷 淳、金倉 譲、杉山治夫
  • Organizer: 第74回日本血液学会総会
  • Place of Presentation: 京都
• [Presentation] Cord blood transplantation for adult T-cell leukemia/lymphoma: The JSHCT WG study (2012)
  • Author(s): Kato K, Cho I, Wake A, Uike N, Taniguchi S, Moriuchi Y, Miyazaki Y, Hino M, Akashi K, Sakamaki H, Kato K, Suzuki R, Yamanaka T, Utsunomiya A
  • Organizer: 第74回日本血液学会総会
  • Place of Presentation: 京都
• [Presentation] DLI for 1st hematologic relapse of AML: A retrospective nationwide analysis by JSHCT Adult AML WG. (2012)
  • Author(s): Takami A, Fukuda T, Miyazaki Y, Hino M, 1kanamori H, Morishima Y, Tanaka J, Atsuta Y, Kanda Y, Yamaguchi T, Nakao S, Kuwatsuka Y, Yano S, Yokoyama H
  • Organizer: 第74回日本血液学会総会
  • Place of Presentation: 京都
• [Presentation] Chronic GVHD-related polymyositis and hepatitis that occurred subsequent to a bruise of the thigh. (2012)
  • Author(s): Koh S、koh H, Sakabe M, Yoshida M, Okamura H, Inaba A, Bingo M, Yoshimura T, Nanno S, Nishimoto M, Hayashi Y, Hirose A, Nakamae M, Hagihara K, Nakane T, Terada Y, Nakamae H, Ohsawa M, Hino M
  • Organizer: 第74回日本血液学会総会
  • Place of Presentation: 京都
• [Presentation] 同種造血幹細胞移植後慢性期における心機能障害リスク因子の評価. (2012)
  • Author(s): 西本光孝、中前博久、中根孝彦、康 秀男、林 良樹、中前美佳、吉田全宏、備後真登、岡村浩史、相本瑞樹、間部賢寛、吉村卓朗、稲葉晃子、南野 智、廣瀬朝生、萩原潔通、中尾吉孝、寺田芳樹、日野雅之
  • Organizer: 第34回日本造血細胞移植学会総会
  • Place of Presentation: 大阪
• [Presentation] 同種造血幹細胞移植後好酸球増多およびその程度が移植予後へ与える影響についての検討 (2012)
  • Author(s): 中根孝彦、中前博久、廣瀬朝生、康 秀男、中前美佳、林 良樹、西本光孝、吉田全宏、備後真登、岡村浩史、梅本由香里、稲葉晃子、吉村卓朗、市原弘善、南野 智、萩原潔通、寺田芳樹、日野雅之
  • Organizer: 第34回日本造血細胞移植学会総会
  • Place of Presentation: 大阪
• [Presentation] Risk Factors Affecting Cardiac Left Ventricular Systolic and Diastolic Function and Hypertrophy in the Chronic Phase Post-Allogeneic Hematopietic Cell Transplantation (2011)
  • Author(s): Nishimoto M, Nakamae H, Nakane T, Koh H, Hayashi Y, Nakamae M, Yoshida M, Bingo M, Okamura H, Aimoto M, Manabe M, Yoshimura T, Inaba A, Nanno S, Hirose A, Hagihara K, Nakao Y, Terada Y, Hino M
  • Organizer: 53th American Society of Hematology
  • Place of Presentation: San-Diego,USA
• [Presentation] Serum cytokine profiles in hemophagocytic syndrome after allogeneic hematopoietic cell transplant (2011)
  • Author(s): Koh H、Koh KR、Nakane T、Sakamoto E、Katayama T、Nakamae M、Terada Y、Nakamae H、Yamane T、Hino M
  • Organizer: 第73回日本血液学会
  • Place of Presentation: 名古屋国際会議場, 名古屋
• [Presentation] Risk Factors Affecting Cardiac Left Ventricular Systolic and Diastolic Function and Hypertrophy in the Chronic Phase Post-Allogeneic Hematopietic Cell Transplantation (2011)
  • Author(s): Nishimoto M, Nakamae H, Nakane T, Koh H, Hayashi Y, Nakamae M, Yoshida M, Bingo M, Okamura H, Aimoto M, Manabe M, Yoshimura T, Inaba A, Nanno S, Hino M, et al
  • Organizer: 53th American Society of Hematology
  • Place of Presentation: San Diego
• [Presentation] Double-Unit Cord Blood Transplantation for Hematological Malignancies in Japan: Multicenter Phase II Study (C-SHOT 0507) (2011)
  • Author(s): Wake A, Kai SR, Okada M, Kurata M, Atsuta Y, Ishikawa J, Hino M, Aotsuka N , Kasai M, Misawa M, Taniguchi S, Kato S
  • Organizer: 53th American Society of Hematology
  • Place of Presentation: San Diego
• [Presentation] Serum cytokine profiles in hemophagocytic syndrome after allogeneic hematopoietic cell transplant. (2011)
  • Author(s): Koh H、Koh KR、Nakane T、Sakamoto E、Katayama T、Nakamae M、Terada Y、Nakamae H、Yamane T、Hino M
  • Organizer: 第73回日本血液学会総会
  • Place of Presentation: 名古屋
• [Presentation] 同種造血幹細胞移植の現状 (2011)
  • Author(s): 日野雅之
  • Organizer: 第65回日本交通医学会総会(招待講演)
  • Place of Presentation: 京都
• [Book] 末梢血幹細胞採取.東條有伸編G-CSFの基礎と臨床 (2013)
  • Author(s): 日野雅之、中前博久、梅本由香里
  • Publisher: 医薬ジャーナル社
• [Book] 自家・同種骨髄・末梢血幹細胞の採取方法、ドナーの安全管理神田善伸編、みんなに役立つ造血幹細胞移植の基礎と臨床(改訂版) (2012)
  • Author(s): 日野雅之、中前博久、中根孝彦、梅本由香里
  • Publisher: 医薬ジャーナル社
• [Book] みんなに役立つ造血幹細胞移植の基礎と臨床: 自家・同種骨髄・末梢血幹細胞の採取方法、ドナーの安全管理 (2012)
  • Author(s): 日野雅之、中前博久、中根孝彦、梅本由香里
  • Total Pages: 699
  • Publisher: 医薬ジャーナル社
• [Book] MASS EFFECTを呈したシクロスポリン脳症 溝口秀昭ら（編） 標本に学ぶ血液疾患症例 (2012)
  • Author(s): 日野雅之、康 秀男
  • Total Pages: 427
  • Publisher: 医薬ジャーナル社
• [Book] 内臓播種性水痘帯状疱疹ウイルス感染症［診療のコツ］ 豊嶋崇徳（編） 症例とエビデンスに学ぶ造血細胞移植と感染症 (2011)
  • Author(s): 日野雅之
  • Total Pages: 291
  • Publisher: 医薬ジャーナル社
• [Remarks]
  • URL: http://www.med.osaka-cu.ac.jp/labmed/
• [Remarks] 大阪市立大学・大学院医学研究科 血液腫瘍制御学
  • URL: http://www.med.osaka-cu.ac.jp/labmed/
• [Remarks]
  • URL: http://www.med.osaka-cu.ac.jp/labmed/