Early diagnosis of acute encephalopathy using electroencephalography coherence analysis
| Project/Area Number |
23591497
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Tottori University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
FUKUDA Chisako 鳥取大学, 医学部, 准教授 (60116366)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 急性脳症 / 脳波 / コヒーレンス / 早期診断 / 熱性けいれん / パワースペクトル / デジタル脳波 / 脳波パワースペクトル / 脳波コヒーレンス / けいれん重積 |
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| Research Abstract |
It is difficult to distinguish between acute encephalopathies with poor prognosis and febrile seizures or epileptic seizures with favorable prognosis using visual electroencephalography (EEG) analysis. Therefore, digital EEG analysis was applied to distinguish between them. Child patients with acute encephalopathies, febrile seizures, or epileptic seizures were the subjects and digital EEGs recorded during acute periods were used for this study. Neurological sequelae were graded into 6 categories: vegetative state, profound mental retardation, severe retardation, moderate retardation, mild retardation , and normal. 1) The EEG power spectra of the theta band was decreased in vegetative state at the frontal region. 2) Frontal-posterior EEG coherence was low in mild to moderate mental retardation groups and high in normal group. Therefore, digital EEG analysis would be a useful tool to diagnose acute encephalopathy with poor prognosis.
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Report
(4 results)
Research Products
(35 results)
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[Journal Article] De novo mutations in SLC35A2 encoding a UDP-galactose transporter cause early-onset epileptic encephalopathy2013
Author(s)
Kodera H, Nakamura K, Osaka H, Maegaki Y, Haginoya K, Mizumoto S, Kato M, Okamoto N, Iai M, Kondo Y, Nishiyama K, Tsurusaki Y, Nakashima M, Miyake N, Hayasaka K, Sugahara K, Yuasa I, Wada Y, Matsumoto N, Saitsu H
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Journal Title
Hum Mutat
Volume: 34(12)
Pages: 1708-14
Related Report
Peer Reviewed
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[Journal Article] De novo mutations in SLC35A2 encoding a UDP-galactose transporter cause early-onset epileptic encephalopathy2013
Author(s)
Kodera H, Nakamura K, Osaka H, Maegaki Y, Haginoya K, Mizumoto S, Kato M, Okamoto N, Iai M, Kondo Y, Nishiyama K, Tsurusaki Y, Nakashima M, Miyake N, Hayasaka K, Sugahara K, Yuasa I, Wada Y, Matsumoto N, Saitsu H.
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Journal Title
Hum Mutat
Volume: 34
Issue: 12
Pages: 1708-1714
DOI
Related Report
Peer Reviewed
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[Journal Article] MECP2 duplication syndrome in both genders.2013
Author(s)
Shimada S, Okamoto N, Ito M, Arai Y, Momosaki K, Togawa M, Maegaki Y, Sugawara M, Shimojima K, Osawa M, Yamamoto T
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Journal Title
Brain Dev
Volume: 35(5)
Issue: 5
Pages: 411-419
DOI
Related Report
Peer Reviewed
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[Presentation] 体性感覚誘発電位における前頭部導出N30消失例の検討 小脳との関連性2013
Author(s)
高森 稔弘, 福田 千佐子, 橋本 裕希, 細田 優太, 宮本 直樹, 村田 あや, 大栗 聖由, 佐藤 研吾, 広岡 保明, 前垣 義弘, 冨田 豊
Organizer
日本臨床神経生理学会学術集会
Place of Presentation
高知市、高知県立県民文化ホール
Related Report
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