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Development of innovative treatment and diagnostic methods for ADHD children comorbid with ASD

Research Project

Project/Area Number 23591519
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Pediatrics
Research InstitutionKurume University

Principal Investigator

YAMASHITA Yushiro  久留米大学, 医学部, 教授 (90211630)

Co-Investigator(Kenkyū-buntansha) MATSUISHI Toyojiro  久留米大学, 医学部, 教授 (60157237)
NAGAMITSU Shinichiro  久留米大学, 医学部, 准教授 (30258454)
NISHI Yoshihiro  久留米大学, 医学部, 講師 (20352122)
OKAMURA Hisayoshi  久留米大学, 高次脳疾患研究所, 助教 (00454918)
EGAMI Chiyomi  福岡県立大学, 看護学部, 講師 (50541778)
中島 範子  佐賀大学, 文化教育学部, 助教 (10555080)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords注意欠如多動性障害 / 自閉症スペクトラム障害 / 治療 / 診断 / 行動療法 / サマートリートメントプログラム / 併存症 / 微細神経徴候 / 注意欠陥多動性障害 / 夏季治療プログラム / 前腕回内回外運動 / Stroop課題 / NIRS / ADHD / Summer Treatment Program / 国際研究者交流 / 国際情報交流 / アメリカ合衆国
Research Abstract

The purpose of this study was to demonstrate the efficacy of summer treatment program (STP) in ADHD children comorbid with ASD compared to children with ADHD. The subjects were sixty-nine elementary school children with ADHD who participated in STP during 2008-11. Among them 16 ADHD children were comorbid with ASD. Behavioral evaluation during STP and ADHD rating Scale were analyzed and there were no difference in the efficacy of STP between ADHD group and ADHD comorbid with ASD group.
The objective method for evaluating diadochokinesia was newly developed and 3 parameters were analyzed 1) Synchronicity of movements in both hands, 2) Followability of tempo, 3) Stability of the posture (movements of elbows and arms other than pronation/supination) were compared between the 2 groups. There were differences in these 3 parameters between the 2 groups suggesting that this method may be useful in distinguishing the 2 groups.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (36 results)

All 2014 2013 2012 2011 Other

All Journal Article (8 results) (of which Peer Reviewed: 6 results) Presentation (26 results) (of which Invited: 3 results) Book (2 results)

  • [Journal Article] Impaired exploratory eye movement in children with Asperger's syndrome2013

    • Author(s)
      Ohya T,MoritaK, Yamashita Y, Egami C, Ishii Y, Nagamitsu S, Matsuishi T
    • Journal Title

      Brain & Development

      Volume: 36(3) Pages: 241-7

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impaired exploratory eye movement in children with Asperger's syndrome2013

    • Author(s)
      Takashi Ohya, Kiichiro Morita, Yushiro Yamashita, Chiyomi Egami, Youhei Ishii, Shinichiro Nagamitsu, Toyojiro Matsuishi
    • Journal Title

      Brain and Development

      Volume: in press Issue: 3 Pages: 241-7

    • DOI

      10.1016/j.braindev.2013.04.005

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Kana reading disability and Dac-Naglieri Cognitive Assesment System findings in children with attention deficit hyperactivity disorder2012

    • Author(s)
      Nakashima N,Yamashita Y,Hirata R,Nagamitsu S,Matsuishi T
    • Journal Title

      Pediatrics International

      Volume: 54 Pages: 849-53

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 特集-小児診療のピットフォールII所見の診かたと対応落ち着きがない2012

    • Author(s)
      山下裕史朗
    • Journal Title

      臨床と研究

      Volume: 89 Pages: 619-23

    • Related Report
      2013 Final Research Report
  • [Journal Article] Kana reading disability and Das-Naglieri Cognitive Assessment System findings in children with attention deficit hyperactivity disorder.2012

    • Author(s)
      Nakashima N, Yamashita Y, Hirata R, Nagamitsu S, Matsuishi T.
    • Journal Title

      Pediatr Int

      Volume: 54 Issue: 6 Pages: 849-53

    • DOI

      10.1111/j.1442-200x.2012.03694.x

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 特集-小児診療のピットフォールII 所見の診かと対応 落ち着きがない.2012

    • Author(s)
      山下裕史朗
    • Journal Title

      臨床と研究

      Volume: 89 Pages: 619-23

    • Related Report
      2012 Research-status Report
  • [Journal Article] Summer treatment program for children with attention deficit hyperactivity disorder : Japanese experience in 5 years2011

    • Author(s)
      Yamashita Y,Mukasa A,Honda Y,Kunisaki C,Koutaki J,Tada Y,Egami C,Kodama N,Nakashima M,Nagamitsu S,Matsuishi T
    • Journal Title

      Brain & Development

      Volume: 33 Pages: 260-7

    • NAID

      10029561056

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Summer treatment program for children with attention deficit hyperactivity disorder: Japanese experience in 5 years.2011

    • Author(s)
      Yamashita Y, Mukasa A, Anai C, Honda Y, Kunisaki C, Koutaki J, Tada Y, Egami C, Kodama N, Nakashima M, Nagamitsu SI, Matsuishi T
    • Journal Title

      Brain & Development

      Volume: 33 Pages: 260-7

    • NAID

      10029561056

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Quoluty of life reported by children with ADHD and their mothers who participated in a summer treatment program2014

    • Author(s)
      Yamashita Y
    • Organizer
      The 2nd Asian Congress on ADHD
    • Place of Presentation
      東京
    • Year and Date
      2014-03-09
    • Related Report
      2013 Final Research Report
  • [Presentation] The objective evaluation of diadochokinesia : a comparison between typically developing children and children with ADHD2014

    • Author(s)
      Yamashita Y
    • Organizer
      The 2nd Asian Congress on ADHD
    • Place of Presentation
      東京
    • Year and Date
      2014-03-09
    • Related Report
      2013 Final Research Report
  • [Presentation] Summer treatment program as a comprehensive treatment of ADHD2014

    • Author(s)
      Yamashita Y
    • Organizer
      10th HY ADHD WORKSHOP
    • Place of Presentation
      ソウル
    • Year and Date
      2014-02-05
    • Related Report
      2013 Final Research Report
  • [Presentation] Summer treatment program as a comprehensive tretment of ADHD2014

    • Author(s)
      Yamashita Y
    • Organizer
      10th HY ADHD WORKSHOP
    • Place of Presentation
      ソウル
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] The objective evalution of diadochokinesia : a comparison between typically developing children and children with ADHD2014

    • Author(s)
      Yamashita Y
    • Organizer
      The 2nd Asian Congress on ADHD
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Quolity of life reported by children with ADHD and their moters who participated in a summer tretment program2014

    • Author(s)
      Yamashita Y
    • Organizer
      The 2nd Asian Congress on ADHD
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 前腕回内回外運動の定量的評価システムを用いたADHD児とAS併存児の比較2013

    • Author(s)
      金子美樹、大矢崇志、山下裕史朗、松石豊次郎、穴井千鶴
    • Organizer
      第110回日本小児精神神経学会
    • Place of Presentation
      名古屋
    • Year and Date
      2013-11-09
    • Related Report
      2013 Final Research Report
  • [Presentation] Summer treatment programの効果:ASD併存ADHDとADHD単独例の比較2013

    • Author(s)
      山下裕史朗
    • Organizer
      第116回日本小児科学会学術集会
    • Place of Presentation
      広島
    • Year and Date
      2013-04-19
    • Related Report
      2013 Final Research Report
  • [Presentation] Summer treatment progamの効果:ASD併存ADHDとADHD単独例の比較2013

    • Author(s)
      山下 裕史朗
    • Organizer
      第116回日本小児科学術集会
    • Place of Presentation
      広島
    • Related Report
      2013 Annual Research Report
  • [Presentation] An examination of developmental trajectories for cognitive functions in healthy children and children with ADHD, and effects of summer treatment program2012

    • Author(s)
      Yamashita Y,Egami C,Shibuya I,Ohya T, Nagamitsu S, Mukasa A, Matsuishi T
    • Organizer
      1st Asian Congress of ADHD
    • Place of Presentation
      ソウル
    • Year and Date
      2012-11-02
    • Related Report
      2013 Final Research Report
  • [Presentation] ADHD児のサマートリートメントプログラム7年間の実践-成果と課題-2012

    • Author(s)
      山下裕史朗、家村明子、中島正幸、松石豊次郎、藤田史恵、向笠章子、原田敏男
    • Organizer
      第60回九州学校保健学会
    • Place of Presentation
      福岡
    • Year and Date
      2012-08-19
    • Related Report
      2013 Final Research Report
  • [Presentation] Cortisol awakening response improves after summer treatment program for children with ADHD2012

    • Author(s)
      Yamashita Y
    • Organizer
      12th International Child Neurology Congress & 11th Asian and Oceanian Child Neurology Congress
    • Place of Presentation
      ブリスベン
    • Year and Date
      2012-05-27
    • Related Report
      2013 Final Research Report
  • [Presentation] ADHDに対する薬物や行動療法を用いた最新の治療2012

    • Author(s)
      山下裕史朗
    • Organizer
      第54回日本小児神経学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-05-17
    • Related Report
      2013 Final Research Report
  • [Presentation] 注意欠陥多動性障害のエビデンスにもとづく治療法2012

    • Author(s)
      山下裕史朗
    • Organizer
      第115回日本小児科学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2012-04-20
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] AD/HDの客観的評価法:外来で可能な機能障害、認知機能の評価法(日本AD/HD)2012

    • Author(s)
      山下裕史朗
    • Organizer
      第3回総会
    • Place of Presentation
      東京
    • Year and Date
      2012-03-18
    • Related Report
      2013 Final Research Report
  • [Presentation] An examination of developmental trajectories for cognitive functions in healthy children and children with ADHD, and effects of summer treatment program.2012

    • Author(s)
      Yushiro Yamashita, Chiyomi Egami, Ikuhiko Shibuya, Takashi Ohya, Shinishiro Nagamitsu, Akiko Mukasa, Toyojiro Matsuishi
    • Organizer
      1st Asian Congress of ADHD
    • Place of Presentation
      Seoul
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Cortisol awakening response improves after sumer treatment program for children with ADHD2012

    • Author(s)
      Yushiro Yamashita
    • Organizer
      12th International Child Neurology Congress & 11th Asian and Oceanian Child Neurology Congress
    • Place of Presentation
      Brisbane
    • Related Report
      2012 Research-status Report
  • [Presentation] ADHDに対する薬物や行動療法を用いた最新の治療2012

    • Author(s)
      山下裕史朗
    • Organizer
      第54回に本小児神経学会総会
    • Place of Presentation
      札幌
    • Related Report
      2012 Research-status Report
  • [Presentation] Is the comprehensive summer treat program for children with ADHD effective to autism spectrum disorder co-morbid with ADHD?2011

    • Author(s)
      Yamashita Y,Egami C,Tada Y,Mukasa A,Anai C,Honda Y,Kunisaki C,Nagamitsu S,Matsuishi T
    • Organizer
      Joint Academic Conference on Autism Spectrum Disorders
    • Place of Presentation
      東京
    • Year and Date
      2011-12-04
    • Related Report
      2013 Final Research Report
  • [Presentation] ADHDサマートリートメントプログラムで起床時コルチゾール反応が改善する2011

    • Author(s)
      山下裕史朗、岡村尚昌、渋谷郁彦、原宗嗣、河野敬子、家村明子、中島正幸、永光信一郎、松石豊次郎
    • Organizer
      第114回日本小児科学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-12
    • Related Report
      2013 Final Research Report
  • [Presentation] Summer Treatment Program for children with ADHD : A Japanese experience for 6 years2011

    • Author(s)
      Yamashita Y
    • Organizer
      3rd World Congress of Asian Psychiatry
    • Place of Presentation
      メルボルン
    • Year and Date
      2011-08-01
    • Related Report
      2013 Final Research Report
  • [Presentation] Summer Treatment Program for children with ADHD:A Japanese experience for 6 years.2011

    • Author(s)
      Yamashita Y
    • Organizer
      3rd World Congress of Asian Psychiatry
    • Place of Presentation
      Melbourne, Australia
    • Related Report
      2011 Research-status Report
  • [Presentation] Is the comprehensive summer treat program for children with ADHD effective to autism spectrum disorder co-morbid with ADHD?2011

    • Author(s)
      Yamashita Y, Egami C, Tada Y, Muakasa A, Anai C, Honda Y, Kunisaki C, Nagamitsu S, Matsuishi T
    • Organizer
      Joint Academic Conference on Autism Spectrum Disorders
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2011 Research-status Report
  • [Presentation] ADHDサマートリートメントプログラムで起床時コルチゾール反応が改善する.2011

    • Author(s)
      山下裕史朗、岡村尚昌、澁谷郁彦、原宗嗣、河野敬子、家村明子、中島正幸、永光信一郎、松石豊次郎
    • Organizer
      第114回日本小児科学会総会
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Presentation] AD/HDの客観的評価法:外来で可能な機能障害、認知機能の評価法

    • Author(s)
      山下裕史朗
    • Organizer
      日本AD/HD第3回総会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] ADHD児のサマートリートメントプログラム7年間の実践ー成果と課題ー

    • Author(s)
      山下裕史朗、家村明子、中島正幸、松石豊次郎、藤田史恵、向笠章子、原田敏男
    • Organizer
      第60回九州学校保健学会
    • Place of Presentation
      福岡
    • Related Report
      2012 Research-status Report
  • [Book] 別冊【発達31】ADHDの理解と援助サマートリートメントプログラム2011

    • Author(s)
      山下裕史朗
    • Total Pages
      6
    • Publisher
      ミネルヴァ書房
    • Related Report
      2013 Final Research Report
  • [Book] 別冊【発達31】ADHDの理解と援助 サマートリートメントプログラム2011

    • Author(s)
      山下裕史朗
    • Total Pages
      6
    • Publisher
      ミネルヴァ書房
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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