| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Research Abstract |
I made a vasculitis animal model of the Kawasaki disease resemblance,and elucidated migration of a vascular smooth muscle cell from a media by the destruction of the inner elasticity band with a vasculitis histologically in the subendothelial site.
Furthermore, the possibility that the vascular smooth muscle cell which migrated in the subendothelial site was transformed in a secretion type from a constitution type by the expression of transcriptional factors such as KLF5 and Egr-1 was suggested. But enough estimation was not accomplished about the function and response mechanism of a transformed vascular smooth muscle cell.
|
