Verification of pathogenecity of Merkel cell polyoma virus in skin neoplasms
| Project/Area Number |
23591610
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Dermatology
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| Research Institution | Hirosaki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKANO Hajime 弘前大学, 大学院医学研究科, 准教授 (90281922)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | メルケル細胞癌 / ポリオ-マ-ウイルス / immuno PCR / ポリオーマーウイルス / 皮膚悪性腫瘍 / ポリオーマウイルス |
|---|
| Research Abstract |
We have experienced ten cases of Merkel cell carcinoma in this period. There were six males and four females, ranging in age 65 to 80 years ( mean and median 75 years).8 of the cases presented on the face, each of two cases, upper extremity and lower extremity.Precursor lesions were not found.On initial treatment, Resection were performed in 8 cases, on the other hand, radiation therapy were performed in two cases. Unfortunately, in all samples of this series, Polyoma virus were undetectable. Also, in situ immune PCR, positive findings could be obtained regardless of many changes of PCR conditions.
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Report
(4 results)
Research Products
(39 results)
