| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Outline of Final Research Achievements |
The side effects arising from treatment with antipsychotic drugs, such as obesity and glycolipid metabolism disorder are major side effects that affect the vital prognosis in schizophrenia patients, but their pathology and prevention methods remain unknown. The present research clarifies the following matters, contributing to the prevention of the serious side effects of antipsychotic drugs: (1) There are differences in the frequency at which such risks occur during the administration of antipsychotic drugs; (2) It is possible to predict obesity and glycolipid metabolism disorder from the blood adipokine concentration and genetic polymorphism.
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