The effects of the gene-environmental interaction on the formation of personality traits

• Project/Area Number: 23591693
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: Yamagata University
• Principal Investigator: OTANI Koichi 山形大学, 医学部, 教授 (00194192)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2012: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
• Keywords: 精神病理学 / 養育環境 / 遺伝‐環境相互作用 / データ解析 / 公表準備中 / 遺伝 / 人格 / うつ病 / 遺伝的要因 / 相互・相関作用

Research Abstract

The present study showed that there was significant main effect of the monoamine oxidase A polymorphism on novelty seeking, while significant interaction effect between the polymorphism and maternal care on reward dependence was found in 767 healthy subjects. Meanwhile, there was significant interaction effect between the serotonin transporter polymorphism and maternal protection on reward dependence in 590 healthy subjects. I am going to publish these findings.
As part of the present study, we examined the comprehensive relationships among parental rearing, interpersonal sensitivity, sociotropy-autonomy, and dysfunctional attitudes. These findings were made public in the form of 5 articles.

Research Products

• [Journal Article] Correlations of interpersonal sensitivity with negative working models of the self and other : evidence for link with attachment insecurity (2014)
  • Author(s): Otani K, Suzuki A, Matsumoto Y, Shibuya N, Sadahiro R, Enokido M
  • Journal Title: Ann Gen Psychiatry Volume: 13 Pages: 5-5
  • Peer Reviewed
• [Journal Article] Correlations of interpersonal sensitivity with negative working models of the self and other: evidence for link with attachment insecurity. (2014)
  • Author(s): Otani K, Suzuki A, Matsumoto Y, Shibuya N, Sadahiro R, Enokido M.
  • Journal Title: Ann Gen Psychiatry Volume: 13 Issue: 1 Pages: 5-5
  • DOI: 10.1186/1744-859x-13-5
  • Peer Reviewed
• [Journal Article] Parental overprotection engenders dysfunctional attitudes about achievement and dependency in a gender-specific manner (2013)
  • Author(s): Otani K, Suzuki A, Matsumoto Y, Shibuya N, Sadahiro R, Enokido M
  • Journal Title: BMC Psychiatry Volume: 13 Pages: 345-345
  • Peer Reviewed
• [Journal Article] Relationship of the 24-item dysfunctional attitude scale with the temperament and character inventory in healthy subjects (2013)
  • Author(s): Otani K, Suzuki A, Matsumoto Y, Shibuya N, Sadahiro R, Enokido M, Kamata M
  • Journal Title: Nord J Psychiatry Volume: 67 Pages: 388-392
  • Peer Reviewed
• [Journal Article] Relationship of the 24-item dysfunctional attitude scale with the temperament and character inventory in healthy subjects. (2013)
  • Author(s): Otani K, Suzuki A, Matsumoto Y, Shibuya N, Sadahiro R, Enokido M, Kamata M.
  • Journal Title: Nord J Psychiatry Volume: 67 Issue: 6 Pages: 388-392
  • DOI: 10.3109/08039488.2012.748092
  • Peer Reviewed
• [Journal Article] Parental overprotection engenders dysfunctional attitudes about achievement and dependency in a gender-specific manner. (2013)
  • Author(s): Otani K, Suzuki A, Matsumoto Y, Shibuya N, Sadahiro R, Enokido M
  • Journal Title: BMC Psychiatry Volume: 13 Issue: 1 Pages: 345-345
  • DOI: 10.1186/1471-244x-13-345
  • Peer Reviewed
• [Journal Article] Interpersonal sensitivity is correlated with sociotropy but not with autonomy in healthy subjects (2012)
  • Author(s): Otani K, Suzuki A, Kamata M, Matsumoto Y, Shibuya N, Sadahiro R
  • Journal Title: J Nerv Ment Dis Volume: 200 Pages: 153-155
  • Peer Reviewed
• [Journal Article] Parental overprotection increases sociotropy with gender specificity in parents and recipients (2012)
  • Author(s): Otani K, Suzuki A, Kamata M, Matsumoto Y, Shibuya N, Sadahiro R, Enokido M
  • Journal Title: J Affect Disord Volume: 136 Pages: 824-827
  • Peer Reviewed
• [Presentation] 愛着理論とうつ病 (2013)
  • Author(s): 大谷浩一
  • Organizer: 第20回日本精神科看護学術集会ランチョンセミナー
  • Place of Presentation: 山形、山形テルサ
  • Year and Date: 2013-11-02
• [Presentation] うつ病親和性について-認知理論と愛着理論を中心に- (2013)
  • Author(s): 大谷浩一
  • Organizer: 平成25年度山形鵬櫻会総会
  • Place of Presentation: 山形、メトロポリタン山形
  • Year and Date: 2013-08-17
• [Presentation] うつ病親和性について-認知理論と愛着理論を中心に- (2013)
  • Author(s): 大谷浩一
  • Organizer: 第13回阪神不安気分障害研究会
  • Place of Presentation: 大阪、ホテルグランディア大阪
  • Year and Date: 2013-02-07
• [Presentation] うつ病親和性について－認知理論と愛着理論を中心に- (2013)
  • Author(s): 大谷浩一
  • Organizer: 平成25年度山形鵬櫻会総会
  • Place of Presentation: 山形市、メトロポリタン山形
  • Invited
• [Presentation] 愛着理論とうつ病 (2013)
  • Author(s): 大谷浩一
  • Organizer: 第20回日本精神科看護学術集会ランチョンセミナー
  • Place of Presentation: 山形市、山形テルサ
  • Invited
• [Presentation] うつ病親和性について-認知理論と愛着理論を中心に- (2013)
  • Author(s): 大谷浩一
  • Organizer: 第13回阪神不安気分障害研究会
  • Place of Presentation: 大阪、ホテルグランヴィア大阪
  • Invited
• [Presentation] うつ病と現在社会 (2012)
  • Author(s): 大谷浩一
  • Organizer: 第32回心のフェスティバル
  • Place of Presentation: 山形、霞城セントラル
  • Year and Date: 2012-11-07
• [Presentation] 愛着理論とうつ病 (2012)
  • Author(s): 大谷浩一
  • Organizer: 旭川学術講演会
  • Place of Presentation: 旭川、旭川グランドホテル
  • Year and Date: 2012-09-28
• [Presentation] うつ病の心理社会的側面 (2012)
  • Author(s): 大谷浩一
  • Organizer: 新庄最上地区学術講演会
  • Place of Presentation: 新庄、県立新庄病院
  • Year and Date: 2012-09-03
• [Presentation] うつ病親和性について-認知理論と愛着理論を中心に- (2012)
  • Author(s): 大谷浩一
  • Organizer: 福岡県精神科病院協会学術講演会
  • Place of Presentation: 福岡、西鉄グランドホテル
  • Year and Date: 2012-07-17
• [Presentation] うつ病の心理学:認知療法を中心に (2012)
  • Author(s): 大谷浩一
  • Organizer: 置賜精神科セミナー
  • Place of Presentation: 米沢、東京第一ホテル米沢
  • Year and Date: 2012-06-01
• [Presentation] 愛着の精神病理 (2012)
  • Author(s): 大谷浩一
  • Organizer: 荘内精神科セミナー
  • Place of Presentation: 鶴岡、東京第一ホテル鶴岡
  • Year and Date: 2012-04-18
• [Presentation] 愛着の精神病理 (2012)
  • Author(s): 大谷浩一
  • Organizer: 庄内精神科セミナー
  • Place of Presentation: 鶴岡、東京第一ホテル鶴岡
  • Invited
• [Presentation] うつ病の心理学：認知理論を中心に (2012)
  • Author(s): 大谷浩一
  • Organizer: 置賜精神科セミナー
  • Place of Presentation: 米沢、東京第一ホテル米沢
  • Invited
• [Presentation] うつ病と現在社会 (2012)
  • Author(s): 大谷浩一
  • Organizer: 第32回こころのフェスティバル
  • Place of Presentation: 山形、霞城セントラル
  • Invited