Algorithm for estimation of brain structural location from head surface shape in young children

• Project/Area Number: 23591697
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: Kanazawa University
• Principal Investigator: KIKUCHI Mitsuru 金沢大学, 子どものこころの発達研究センター, 特任准教授 (00377384)
• Co-Investigator(Kenkyū-buntansha): SANADA Shigeru 金沢大学, 保健学系, 教授 (50020029) ; NIIDA Yo 金沢大学, 子どものこころの発達研究センター, 特任准教授 (40293344)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: 幼児 / 脳座標 / MRI / 脳画像 / 小児

Research Abstract

If the brain structural coordinates could be estimated using the individual head shape, magnetoencephalography would be more ideal brain functional imaging methods especially for young human children. We propose an algorithm to estimate brain coordinates with reference to the head surface shape in preschool children. The mean error of landmarks was 13.6 ± 5.3 mm on the head surface and 18.5 ± 12.4 mm in the intracranial structure between estimated and actual brain coordinates.

Research Products

• [Journal Article] Anterior prefrontal hemodynamic connectivity in conscious 3- to 7-year-old children with typical development and autism spectrum disorder. (2013)
  • Author(s): Kikuchi, M., Yoshimura, Y., Shitamichi, K., Ueno, S., et al., Remijn, G.B., Takahashi, T., Suzuki, M., Higashida, H., Minabe, Y.
  • Journal Title: PloSONE Volume: 8 Issue: 2 Pages: 56087-56087
  • DOI: 10.1371/journal.pone.0056087
  • Peer Reviewed
• [Journal Article] A custom Magnetoencephalography device reveals brain connectivity and high reading/decoding ability in children with autism. (2013)
  • Author(s): Kikuchi, M., Yoshimura, Y., Shitamichi, K., Ueno, S., et al., Remijn, G.B., Takahashi, T., Suzuki, M., Higashida, H., Minabe, Y.
  • Journal Title: Scientific Reports Volume: 3 Issue: 1 Pages: 1139-1139
  • DOI: 10.1038/srep01139
  • Peer Reviewed
• [Journal Article] Algorithm for estimation of brain structural location from head surface shape in young children (2012)
  • Author(s): Hayashi N., et al
  • Journal Title: NeuroReports Volume: 28 Issue: 5 Pages: 299-303
  • DOI: 10.1097/wnr.0b013e3283511de0
  • Peer Reviewed
• [Journal Article] Language performance and auditory evoked fields in 2- to 5-year-old children (2012)
  • Author(s): Yoshimura, Y., Kikuchi, M., Shitamichi, K., Ueno, S., Remijn, G.B., et al
  • Journal Title: European Journal of Neuroscience Volume: 35 Issue: 4 Pages: 644-650
  • DOI: 10.1111/j.1460-9568.2012.07998.x
  • Peer Reviewed
• [Journal Article] Lateralized theta wave connectivity and language performance in 2-to 5-year-old children (2011)
  • Author(s): Kikuchi, M
  • Journal Title: J Neurosci Volume: Vol.31 Issue: 42 Pages: 14984-14988
  • DOI: 10.1523/jneurosci.2785-11.2011
  • Peer Reviewed
• [Presentation] 幼児用MEGによる未就学広汎性発達障害児の生理学的検討 (2012)
  • Author(s): 菊知充
  • Organizer: 第34回日本生物学的精神医学会
  • Place of Presentation: 神戸国際会議場(兵庫県)
  • Year and Date: 2012-09-30
• [Presentation] MEG-NIRS 統合機の開発:幼児への応用 (2012)
  • Author(s): 菊知充
  • Organizer: 第14回ヒト脳機能マッピング学会
  • Place of Presentation: 京王プラザホテル札幌(北海道)
  • Year and Date: 2012-07-06
• [Presentation] MEG-NIRS 統合機の開発：幼児への応用 (2012)
  • Author(s): 菊知充
  • Organizer: 第14回ヒト脳機能マッピング学会
  • Place of Presentation: 京王プラザホテル札幌（北海道）
  • Invited
• [Presentation] 幼児用MEGによる未就学広汎性発達障害児の生理学的検討 (2012)
  • Author(s): 菊知充
  • Organizer: 第34回日本生物学的精神医学会
  • Place of Presentation: 神戸国際会議場（兵庫県）
• [Presentation] Development of method for creation of a personalized brain template to allow superimposition of MEG and NIRS,Radiological Society of North America (RSNA) (2011)
  • Author(s): Hayashi,N.
  • Organizer: 97th Scientific Assembly and Annual Meeting
  • Place of Presentation: McCormick Place(米シカゴ)
• [Presentation] Development of method for creation of a personalized brain template to allow superimposition of MEG and NIRS (2011)
  • Author(s): Hayashi N, Kikuchi M, Sanada S et al.
  • Organizer: Radiological Society of North America (RSNA) 2011 97th Scientific Assembly and Annual Meeting
  • Place of Presentation: McCormick Place, America
• [Remarks]
  • URL: http://bambiplan.w3.kanazawa-u.ac.jp/
• [Patent(Industrial Property Rights)] 脳画像生成装置、脳画像精製方法、及びプログラム (2012)
  • Inventor(s): 林則夫 菊知充 真田茂 三邉義雄 上野沙奈絵 下道喜代美
  • Industrial Property Rights Holder: 国立大学法人金沢大学
  • Industrial Property Number: 2012-279606
  • Filing Date: 2012-12-21
• [Patent(Industrial Property Rights)] 脳画像生成装置、脳画像精製方法、及びプログラム (2012)
  • Inventor(s): 林則夫 菊知充 真田茂 三邉義雄 上野沙奈絵 下道喜代美
  • Industrial Property Rights Holder: 国立大学法人金沢大学
  • Industrial Property Rights Type: 特許
  • Filing Date: 2012-12-21