neural basis of derangement of ego in schizophrenia
| Project/Area Number |
23591712
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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|---|
| Keywords | 統合失調症 / 脳磁図 / ＭＲＩ / 自我障害 / 双極性障害 / MRI |
|---|
| Research Abstract |
The current study investigated the visually evoked oscillations for subject's family name using magnetoencephalography (MEG). Twenty SZ patients and 20 normal controls (NC) participated in this study. The MEG signals were acquired using a whole-head, 306-channel sensor array. In this study, we presented visually four types of Japanese character string (kana): (1) subject's family name (30%), (2) another family name (30%), (3) meaningless string (30%), (4) a Japanese city name (target, 10%). In the mean power of evoked high gamma oscillations between 190msec and 210msec after stimulus onset, a repeated measures ANOVA demonstrated significant stimulus-by-group interactions. In post-hoc analyses, NC showed a significant difference (subject's family name>another family name>meaning less string), but there was no significant stimulus effect in SZ. The high gamma frequency neural oscillatory abnormalities of SZ may indicate a new evidence for neural basis of derangement of ego.
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Report
(4 results)
Research Products
(61 results)
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[Presentation] 統合失調症における視覚認知障害 自己関連刺激に対する脳磁図研究2013
Author(s)
小原尚利, 小田祐子, 平野昭吾, 中村一太, 織部直弥, 土本利架子, 上野雄文, 前川俊彦, 平野羊嗣, 勝木聡美, 神庭重信, 鬼塚俊明
Organizer
第109回日本精神神経学会学術総会
Place of Presentation
福岡市
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