Development of evaluation methods using the brain white matter structural analysis for pressure and infiltration of intracranial lesions

• Project/Area Number: 23591749
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: University of Tsukuba
• Principal Investigator: MATSUSHITA AKIRA 筑波大学, サイバニクス研究コア, 助教 (80532481)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 白質マッピング / 拡散テンソル画像 / 標準脳 / 脳機能画像 / 脳腫瘍 / 浸潤 / 圧迫 / 拡散強調画像

Research Abstract

We produced the method to remove the unwished signal and noise that came from others than brain automatically. This method succeeded that the calculation accuracy increased even if the subject had large mass or large ventricle.
On the other hand, we had developed the method to discriminate the high FA structure such as corpus callosum and pyramidal tract. The novel proposed method used all raw images of the diffusion tensor imaging. It had the same accuracy in the structure with high FA value. However, it permitted to discriminate the low and moderate FA structure which had distinguishing fiber structures.

Research Products

• [Journal Article] Development of an MR-compatible sensory stimulation device which provides pin and brush stimulations (2014)
  • Author(s): 村田耕一, 松下明, 五月女康作, 河本浩明, 山海嘉之
  • Journal Title: Transactions of the JSME (in Japanese) Volume: 80 Issue: 810 Pages: DR0028-DR0028
  • DOI: 10.1299/transjsme.2014dr0028
  • NAID: 130003399115
  • ISSN: 2187-9761
  • Peer Reviewed
• [Presentation] Motor task-evoked brain activity changes before and after robot-assistive rehabilitation of chronic gait impairment (2013)
  • Author(s): Akira Matsushita, Kousaku Saotome, Kei Nakai, Hideo Tsurushima, Kiyoshi Eguchi, Yoshiyuki Sankai, Akira Matsumura
  • Organizer: 9th Biennial 2013 Minnesota workshops on high and ultra-high field imaging
  • URL: http://www.cmrr.umn.edu/workshops/Workshop_13/2013Workshop_Flyer.pdf
  • Place of Presentation: Minneapolis
• [Presentation] Motion detection at the cervico-medullary brainstem in patients with Chiari malformation type I using cine-MRI (2013)
  • Author(s): MATSUSHITA A, YOSHIKAWA F, IHARA S, AYUZAWA S, MASUMOTO T and MATSUMURA A
  • Organizer: 第42回日本神経放射線学会
  • URL: http://jsnr42.umin.jp/index.htm
  • Place of Presentation: 福岡
• [Presentation] Automatic Detection of Chiari Type I Malformation-related Displacement from Cine MR Image Sequences Using Statistical and Morphological Features (2012)
  • Author(s): F Yoshikawa, A Matsushita, S Ihara, T Masumoto, A Matsumura
  • Organizer: The Fourth Meeting of the International Society for Hydrocephalus and Cerebrospinal Disorders
  • URL: http://www.hydrocephalus.se/index.html
  • Place of Presentation: Kyoto
• [Presentation] Pilot study of floor-reactive-force generator mounted on MRI compatible lower-extremity motion simulator (2012)
  • Author(s): Ikeda, T., Matsushita, A., Saotome, K., Hasegawa, Y., Sankai, Y
  • Organizer: Paper presented at the Intelligent Robots and Systems (IROS), IEEE/RSJ
  • URL: http://www.iros2012.org/site/
  • Place of Presentation: (Japan Chapter Young Award)
• [Remarks]
  • URL: http://www.tsukuba-gama.org/