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A study of the clinical efficacy and the establishment of simulation systems of preoperative planning of breast cancer using imaging modalities avoiding radiation exposure

Research Project

Project/Area Number 23591759
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionNagoya University

Principal Investigator

SATAKE Hiroko  名古屋大学, 医学部附属病院, 准教授 (00324426)

Co-Investigator(Kenkyū-buntansha) NAGANAWA Shinji  名古屋大学, 医学(系)研究科(研究院), 教授 (50242863)
Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords画像診断 / 乳癌 / MRI / 画像診断学
Outline of Final Research Achievements

This study showed the degree of background parenchymal enhancement (BPE) on preoperative breast MRI affects the diagnosis of tumor extension and surgical planning. Whereas, BPE on breast MRI is associated with menopausal status and background parenchymal findings of US and DWI. Because premenopausal women with heterogeneous background parenchymal echotexture may be predicted to show moderate or marked BPE, scheduling of breast MRI should preferentially be adjusted to the menstrual cycle. One of the challenges for clinical use of preoperative breast MRI is how to transfer prone-MRI information to the operating theatre with a supine surgical position. This study showed that prone-to-supine tumor displacement in the breast differs depending on tumor location and status of breast projection.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (24 results)

All 2015 2014 2013 2012 2011 Other

All Journal Article (7 results) (of which Peer Reviewed: 5 results) Presentation (17 results) (of which Invited: 3 results)

  • [Journal Article] Prediction of prone-to-supine tumor displacement in the breast using patient position change: investigation with prone MRI and supine CT.2015

    • Author(s)
      Satake H, Ishigaki S, Kitano M, Naganawa S.
    • Journal Title

      Breast Cancer

      Volume: in press

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] second look US-切除範囲決定の実際-2013

    • Author(s)
      佐竹弘子、石垣聡子、長縄慎二
    • Journal Title

      臨床画像

      Volume: 29 Pages: 1292-1300

    • Related Report
      2013 Research-status Report
  • [Journal Article] 乳癌-広がり診断-2013

    • Author(s)
      佐竹弘子、石垣聡子、長縄慎二
    • Journal Title

      画像診断

      Volume: 33 Pages: 1044-1051

    • Related Report
      2013 Research-status Report
  • [Journal Article] ^1H-magnetic resonance spectroscopy of the breast at 3.0-T : Comparison of results obtained before and after administration of gadolinium-based contrast agent2012

    • Author(s)
      KAWAI HISASHI
    • Journal Title

      J Magn Reson Imaging

      Volume: 35(3) Issue: 3 Pages: 717-722

    • DOI

      10.1002/jmri.22893

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Diffusion-weighted imaging of breast masses: comparison of diagnostic performance using various apparent diffusion coefficient parameters.2012

    • Author(s)
      Hirano M, Satake H, Ishigaki S, Ikeda M, Kawai H, Naganawa S.
    • Journal Title

      Am J Roentgenol.

      Volume: 198(3) Pages: 717-22

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Early prediction of response to neoadjuvant chemotherapy for locally advanced breast cancer using MRI.2011

    • Author(s)
      Kawamura M, Satake H, Ishigaki S, Nishio A, Sawaki M, Naganawa S.
    • Journal Title

      Nagoya J Med Sci.

      Volume: 73 Pages: 147-56

    • NAID

      120003277474

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Predictive value for malignancy of suspicious breast masses of BI-RADS categories 4 and 5 using ultrasound elastography and MR diffusion-weighted imaging.2011

    • Author(s)
      Satake H, Nishio A, Ikeda M, Ishigaki S, Shimamoto K, Hirano M, Naganawa S.
    • Journal Title

      Am J Roentgenol.

      Volume: 196(1) Pages: 202-9

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Kinetic Parametric Imaging of Breast Cancer using Dynamic Contrast-Enhanced MRI with Routine Clinical Protocols2014

    • Author(s)
      Satake H, Ishigaki S, Kitano M, kawai H, Naganawa S.
    • Organizer
      100th Annual Meeting of radiological Society of North America
    • Place of Presentation
      Chicago (U.S.A.)
    • Year and Date
      2014-11-30 – 2014-12-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] 乳癌のタイプと画像所見2014

    • Author(s)
      佐竹弘子
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      京都府京都市 ホテルグランヴィア京都
    • Year and Date
      2014-09-18 – 2014-09-20
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] ダイナミック造影MRIにおけるトリプルネガティブ乳癌の定量的検討2014

    • Author(s)
      佐竹弘子、石垣聡子、川井恒、北野真利子、長縄慎二
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      京都府京都市 ホテルグランヴィア京都
    • Year and Date
      2014-09-18 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] ダイナミックMRIによる乳癌の造影剤動態2014

    • Author(s)
      佐竹弘子、石垣聡子、川井恒、長縄慎二
    • Organizer
      第22回乳癌学会学術総会
    • Place of Presentation
      大阪府大阪市 大阪国際会議場
    • Year and Date
      2014-07-10 – 2014-07-12
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Translation of Preoperative Breast MRI Findings into the Surgical Field using Real-time Virtual Sonography2013

    • Author(s)
      Satake H, Ishigaki S, Kitano M, Kawai H, Naganawa S
    • Organizer
      99th Radiological Society of North America (RSNA)
    • Place of Presentation
      Chicago, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] 乳腺MRI診断の基本2013

    • Author(s)
      佐竹弘子
    • Organizer
      第72回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2013 Research-status Report
  • [Presentation] 乳腺ダイナミック造影MRI:Tissue 4Dによる定量評価と病理学的予後予測因子との対比2013

    • Author(s)
      石垣聡子、佐竹弘子、川井恒、北野真利子、長縄慎二
    • Organizer
      第72回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2013 Research-status Report
  • [Presentation] ホルモン受容体陽性乳癌におけるダイナミック造影MRIの定量2013

    • Author(s)
      佐竹弘子、石垣聡子、川井恒、北野真利子、長縄慎二
    • Organizer
      第41回日本磁気共鳴医学会大会
    • Place of Presentation
      アスティとくしま(徳島市)
    • Related Report
      2013 Research-status Report
  • [Presentation] 背景乳腺の造影効果が乳癌術前MRIに与える影響について2012

    • Author(s)
      沼波悟古、石垣聡子、佐竹弘子、木村麗子、河村綾希子、川井恒、長縄慎二
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Research-status Report 2011 Research-status Report
  • [Presentation] 乳腺MRIにおける背景乳腺の造影効果の予測2012

    • Author(s)
      河村綾希子、佐竹弘子、石垣聡子、木村麗子、川井恒、長縄慎二、池田充、島本佳寿広
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Research-status Report 2011 Research-status Report
  • [Presentation] 乳腺の腹臥位MRIと背臥位CTにおける病変の移動2012

    • Author(s)
      佐竹弘子、石垣聡子、木村麗子、川井恒、長縄慎二
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 乳癌術前MRIの有用性と問題点2012

    • Author(s)
      佐竹弘子
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      京都
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Prone-to-supine Tumor Displacement of the Breast2012

    • Author(s)
      Satake H, Ishigaki S, Kawai H, Naganawa S
    • Organizer
      98th Radiological Society of North America (RSNA)
    • Place of Presentation
      US (Chicago)
    • Related Report
      2012 Research-status Report
  • [Presentation] Background Parenchymal Enhancement in Preoperative Breast MRI2012

    • Author(s)
      Nunami S, Ishigaki S, Satake H, Kawamura A, Kawai H, Naganawa S
    • Organizer
      98th Radiological Society of North America (RSNA)
    • Place of Presentation
      US (Chicago)
    • Related Report
      2012 Research-status Report
  • [Presentation] 乳腺の腹臥位MRIと背臥位CTにおける病変の移動

    • Author(s)
      佐竹弘子、石垣聡子、木村麗子、川井恒、西尾明子、長縄慎二
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2011 Research-status Report
  • [Presentation] 乳癌の拡散強調像-ADC値で予後因子、予測因子の推測は可能か-

    • Author(s)
      石垣聡子、佐竹弘子、平野真希、川井恒、長縄慎二
    • Organizer
      第19回日本乳癌学会学術総会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Related Report
      2011 Research-status Report
  • [Presentation] MMG・US・MRI拡散強調像によるダイナミックMRIの乳腺造影効果の予測

    • Author(s)
      佐竹弘子、石垣聡子、木村麗子、川井恒、島本佳寿広、長縄慎二
    • Organizer
      第70回日本医学放射線学会総会
    • Place of Presentation
      要旨集
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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