| Project/Area Number |
23591795
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Keio University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
今西 宣晶 慶應義塾大学, 医学部, 准教授 (00184820)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 2重エネルギーCT / 仮想t単色X線CT / monochromatic image / material decomposition / 仮想単純CT / virtual unenhanced CT / pseudoenhancement / 冠動脈 / 腎嚢胞 / 末梢血管 / 2重エネルギーＣＴ / 末梢動脈 |
|---|
| Research Abstract |
We clarified that virtual monochromatic spectral (VMS) images obtained at 70 keV had fewer beam-hardening artifacts than those obtained at 120 kVp for images obtained during evaluations of cardiac perfusion and renal cysts. We also showed that the 70 keV images provided both image noise reduction and an improved contrast-noise ratio, compared with the 120-kVp images, in abdominal CT evaluations. Thus, VMS imaging has the potential to replace 120-kVp CT as the standard CT imaging modality. We also showed that virtual non-contrast images provided CT attenuation values that were equivalent to a true unenhanced image, and the coronary artery calcium scores derived from water density images paralleled those obtained using 120-kVp unenhanced images. However, the diagnostic performance of iodine/calcium-based materials for decomposition images used to evaluate severely calcified coronary arteries was not as high as expected. We plan to continue evaluating material decomposition imaging.
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