320-detector-row computed tomography arteriography using CO2 gas to detect malignant liver tumors

• Project/Area Number: 23591817
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Shiga University of Medical Science
• Principal Investigator: SONODA AKINAGA 滋賀医科大学, 医学部, 助教 (00571051)
• Co-Investigator(Kenkyū-buntansha): OHTA Shinichi 滋賀医科大学, 医学部, 講師 (30583637) ; NITTA Norihisa 滋賀医科大学, 医学部, 講師 (40324587)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2013: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000); Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: CO2 / マルチディテクター / MDCT / ガス / 血管造影 / TACE / 320列MDCT / CO２ / Multidetctor / Angiography / Liver tumore / 320列Area-Detector CT / CO2 angiography

Research Abstract

We present the initial steps for 320-detector-row computed tomography arteriography using CO2 gas to detect the vascular area of malignant liver tumors. We studied six patients with primary and metastatic liver tumors (n=26) and allergic reactions to iodinated contrast media or a tendency for renal failure. CO2 was injected at 1 ml/secinto the common hepatic artery and a CT scan was acquired 12 sec after the start of injection. The detection of the vascular area of the tumor or of intratumor air was evaluated with respect to the relationship between the size and location of the tumors. The vascular area was detected in 17 of the 26 tumors (65.4%). There was a correlation between the detection of the adjacent vascular area on CTA images acquired with the use of CO2 and the tumor site observed on previously-acquired MRI or CT images.320-MDCT CO2 arteriography with microcatheters may be useful for the detection of the vascular area.

Research Products

• [Journal Article] 320-detector-row computed tomography arteriography using CO2 gas to detect malignant liver tumors (2013)
  • Author(s): Sonoda A, Nitta N, Ushio N, Nitta-Seko A, Tomozawa Y, Watanabe S, Ohta S, Takahashi M, Murata K
  • Journal Title: Minim Invasive Ther Allied Technol Volume: 22(2) Pages: 89-96
  • Peer Reviewed
• [Journal Article] 320-detector-row computed tomography arteriography using CO2 gas to detect malignant liver tumors. (2013)
  • Author(s): Sonoda A1, Nitta N, Ushio N, Nitta-Seko A, Tomozawa Y, Watanabe S, Ohta S, Takahashi M, Murata K.
  • Journal Title: Minim Invasive Ther Allied Technol. Volume: Apr;22(2): Issue: 2 Pages: 89-96
  • DOI: 10.3109/13645706.2012.704876
  • Peer Reviewed
• [Presentation] 320-row CT Angiography for Hepatic Tumor Using CO2 Gas instead of Iodinated Contrast Agents (2011)
  • Author(s): 園田明永、新田哲久、渡辺尚武、友澤裕樹、瀬古安由美、大田信一、土屋桂子、大谷秀司、高橋雅士、村田喜代史
  • Organizer: 日本医学放射線学会春季総会