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320-detector-row computed tomography arteriography using CO2 gas to detect malignant liver tumors

Research Project

Project/Area Number 23591817
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionShiga University of Medical Science

Principal Investigator

SONODA AKINAGA  滋賀医科大学, 医学部, 助教 (00571051)

Co-Investigator(Kenkyū-buntansha) OHTA Shinichi  滋賀医科大学, 医学部, 講師 (30583637)
NITTA Norihisa  滋賀医科大学, 医学部, 講師 (40324587)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
KeywordsCO2 / マルチディテクター / MDCT / ガス / 血管造影 / TACE / 320列MDCT / CO2 / Multidetctor / Angiography / Liver tumore / 320列Area-Detector CT / CO2 angiography
Research Abstract

We present the initial steps for 320-detector-row computed tomography arteriography using CO2 gas to detect the vascular area of malignant liver tumors. We studied six patients with primary and metastatic liver tumors (n=26) and allergic reactions to iodinated contrast media or a tendency for renal failure. CO2 was injected at 1 ml/secinto the common hepatic artery and a CT scan was acquired 12 sec after the start of injection. The detection of the vascular area of the tumor or of intratumor air was evaluated with respect to the relationship between the size and location of the tumors. The vascular area was detected in 17 of the 26 tumors (65.4%). There was a correlation between the detection of the adjacent vascular area on CTA images acquired with the use of CO2 and the tumor site observed on previously-acquired MRI or CT images.320-MDCT CO2 arteriography with microcatheters may be useful for the detection of the vascular area.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (3 results)

All 2013 2011

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (1 results)

  • [Journal Article] 320-detector-row computed tomography arteriography using CO2 gas to detect malignant liver tumors2013

    • Author(s)
      Sonoda A, Nitta N, Ushio N, Nitta-Seko A, Tomozawa Y, Watanabe S, Ohta S, Takahashi M, Murata K
    • Journal Title

      Minim Invasive Ther Allied Technol

      Volume: 22(2) Pages: 89-96

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 320-detector-row computed tomography arteriography using CO2 gas to detect malignant liver tumors.2013

    • Author(s)
      Sonoda A1, Nitta N, Ushio N, Nitta-Seko A, Tomozawa Y, Watanabe S, Ohta S, Takahashi M, Murata K.
    • Journal Title

      Minim Invasive Ther Allied Technol.

      Volume: Apr;22(2): Issue: 2 Pages: 89-96

    • DOI

      10.3109/13645706.2012.704876

    • Related Report
      2013 Annual Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 320-row CT Angiography for Hepatic Tumor Using CO2 Gas instead of Iodinated Contrast Agents2011

    • Author(s)
      園田明永、新田哲久、渡辺尚武、友澤裕樹、瀬古安由美、大田信一、土屋桂子、大谷秀司、高橋雅士、村田喜代史
    • Organizer
      日本医学放射線学会春季総会
    • Related Report
      2013 Final Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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