Development of new radiopharmaceuticals for support system of anti-tumor drug therapy.
| Project/Area Number |
23591828
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Osaka University of Pharmaceutical Sciences |
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Principal Investigator |
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| Project Period (FY) |
2011-04-28 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 放射性医薬品 / EGF / チロシンキナーゼ / SPECT / 核医学 / 診断 / 放射性ヨウ素 / 抗癌剤 / 治療効果予測 / 核医学診断 / EGFR / tyrosine kinase / radiopharmacrtical / tumor / シグナル伝達 / ピペリジン誘導体 / 分子イメージング / T790 |
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| Outline of Final Research Achievements |
New radiopharmaceticals which could support a cancer treatment plan.were developed The affinity of new radiopharmacruticals to EGFR-TK wrere weak as imaging probe.Form these result, a side chain greatly influenced activity.From some examination,the prediction of the curative effect of the anticancer drug was got using our new compounds.
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Report
(5 results)
Research Products
(17 results)
