• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Establishment of quantitative evaluation method of admissibility of overlapped re-irradiation using a 3D dose distribution deformable registration technique in past cases

Research Project

Project/Area Number 23591851
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionTokai University

Principal Investigator

AKIBA Takeshi  東海大学, 医学部, 講師 (40276845)

Co-Investigator(Kenkyū-buntansha) KUNIEDA Etsuo  東海大学, 医学部, 教授 (70170008)
YOGO Katsunori  北里大学, 医学(系)研究科(研究院), 助教 (30424823)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords放射線治療学 / 再照射 / 線量分布 / 画像融合 / 放射線治療
Research Abstract

We have established a method of superposition and modification of dose distribution by deformable registration technique. We performed a quantitative analysis of three-dimensional dose distribution further. We constructed a database to investigate the patients who received a overlapped re-irradiation. Overlapped re-irradiation (including proximity) had 340 cases, the treatment effect was almost the same as the initial treatment. There were 29 cases of adverse events of grade 2 or more, there were nine cases of grade 5, it was considered to be carefully in the indication of re-irradiation. Interval between adverse events from re-radiation was the median of 2.6 months, it was found that care should be taken to adverse events of the early re-irradiation.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (12 results)

All 2013 2012 2011

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (7 results) Book (1 results)

  • [Journal Article] Re-irradiation for Metastatic Brain Tumors with Whole-brain Radiotherapy2012

    • Author(s)
      Takeshi Akiba, Etsuo Kunieda, Asuka Kogawa, Tetsuya Komatsu, Yoshifumi Tamai, Yukio Ohizumi
    • Journal Title

      Jpn J Clin Oncol

      Volume: 42(2) Pages: 264-269

    • Related Report
      2013 Final Research Report
  • [Journal Article] 脳転移に対する全脳再照射2012

    • Author(s)
      秋庭健志、古川あす香、玉井好史、小松哲也、國枝悦夫、大泉幸雄
    • Journal Title

      癌の臨床

      Volume: 第58巻第4号 Pages: 199-204

    • Related Report
      2013 Final Research Report
  • [Journal Article] 【再照射】 脳転移に対する全脳再照射2012

    • Author(s)
      秋庭健志, 古川あす香, 玉井好史, 小松哲也, 国枝悦夫, 大泉幸雄
    • Journal Title

      癌の臨床

      Volume: 58 Pages: 199-204

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Re-irradiation for Metastatic Brain Tumors with Whole-brain Radiotherapy2012

    • Author(s)
      Akiba, T
    • Journal Title

      Jpn J Clin Oncol

      Volume: (in press) Issue: 4 Pages: 264-269

    • DOI

      10.1093/jjco/hys007

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] 前立腺癌に対する根治的外部放射線治療における急性有害事象に関連する因子2013

    • Author(s)
      秋庭健志、福澤毅、長尾隆太、小松哲也、玉井好史、國枝悦夫、大泉幸雄
    • Organizer
      日本放射線腫瘍学会第26回学術大会
    • Place of Presentation
      青森市
    • Related Report
      2013 Final Research Report
  • [Presentation] 頭頚部放射線治療におけるPET画像を用いたGTV体積描出の試み2013

    • Author(s)
      広木智之、株木重人、臼井桂介、藤田健太、菊池朋子、戸高秀晴、國枝悦夫
    • Organizer
      日本放射線腫瘍学会第26回学術大会
    • Place of Presentation
      青森市
    • Related Report
      2013 Final Research Report
  • [Presentation] Acute anorectal and urinary toxicities in prostate cancer patients treated with IMRT and 3D-CRT2013

    • Author(s)
      T.Akiba, E.Kunieda, R.Nagao, T.Fukuzawa, A.Kogawa, T.Komatsu, Y.Tamai, Y.Ohizumi
    • Organizer
      2nd ESTRO Forum
    • Place of Presentation
      Geneva, Switzerland
    • Related Report
      2013 Final Research Report
  • [Presentation] 前立腺癌に対する根治的外部放射線治療における急性有害事象に関連する因子2013

    • Author(s)
      秋庭健志
    • Organizer
      日本放射線腫瘍学会第26回学術大会報文集
    • Place of Presentation
      青森市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Acute anorectal and urinary toxicities in prostate cancer patients treated with IMRT and 3D-CRT.2013

    • Author(s)
      T.Akiba
    • Organizer
      2nd ESTRO Forum
    • Place of Presentation
      Geneva
    • Related Report
      2013 Annual Research Report
  • [Presentation] 前立腺癌に対する強度変調放射線治療の急性有害事象2012

    • Author(s)
      秋庭健志
    • Organizer
      日本放射線腫瘍学会第25回学術大会
    • Place of Presentation
      東京国際フォーラム
    • Related Report
      2012 Research-status Report
  • [Presentation] 脳転移に対する前脳再照射2011

    • Author(s)
      秋庭健志, 国枝悦夫, 古川あす香, 小松哲也, 玉井好史, 大泉幸雄
    • Organizer
      日本放射線腫瘍学会第24回学術大会
    • Place of Presentation
      神戸ポートピアホテル
    • Related Report
      2011 Research-status Report
  • [Book] 臨床放射線腫瘍学全身照射2012

    • Author(s)
      秋庭健志、大泉幸雄、他
    • Publisher
      南江堂
    • Related Report
      2013 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi