| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Research Abstract |
Peritoneal and lymph node metastasis is the most frequent pattern of recurrence after curative surgery for gastric cancer. However, such a recurrence is difficult to detect by conventional CT and MRI at an early stage. In the present study, we first developed a new lymph node metastasis model using GFP-tagged tumor cells. Second, we developed a new laparoscopic fluorescence device for detecting metastasis using ICG-labeled antibody as a probe. Using these mouse metastasis model and imaging device, we successfully detected peritoneal metastasis and lymph node metastasis at an early stage with high sensitivity and specificity.
|
