| Project/Area Number |
23592005
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
OHTA Tetsuo 金沢大学, 医学系, 教授 (40194170)
GABATA Toshifumi 金沢大学, 医学系, 教授 (00169806)
I Tsutomu 首都大学東京, 人間健康科学研究科, 教授 (70334753)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2011: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
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| Keywords | 膵頭部癌 / Mesopancreatoduodenum / 腎筋膜前葉 / 後方組織への浸潤 / リンパ行性進展 / 直接浸潤 / 上腸間膜動脈神経叢 / 膵頭神経叢 / mesopancreatoduodenum / 下膵十二指腸動脈 / 後腹膜腔 / リンパ管 / 神経線維 / mesopancreas / 癒合筋膜 |
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| Research Abstract |
Resection of lymphatic basin and clearance of direct invasion are required for curative resection of pancreatic carcinoma. The anterior renal fascia acts as a barrier against retropancreatic invasion. The principle underlying our surgical strategy for resectable pancreatic head carcinoma is total excision of the lymphatic basin of the pancreatic head, which is termed meso-pancreatoduodenum (meso-pd). Our meso-pd concept refers to the mesentery of the pancreatic head and the duodenum, which is a firm and well-vascularized perineural lymphatic layer located dorsal to the pancreas that reaches behind the mesenteric vessels. The meso-pd is fan-shaped and its trunk is the inferior pancreatoduodenal artery, which is a tributary of the SMA. Therefore, a total meso-pd resection was performed with respect to the PLX surrounding the SMA and including the anterior renal fascia.
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