| Project/Area Number |
23592011
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Kochi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KITAGAWA Hiroyuki 高知大学, 教育研究部医療学系, 助教 (10403883)
YATABE Tomoaki 高知大学, 教育研究部医療学系, 助教 (60437720)
UEHARA Yoshio 新潟大学, 医歯(薬)学総合研究科, その他 (60346723)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 人工膵臓 / 糖尿病 / 周術期 / 血糖管理 / 血統管理 |
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| Research Abstract |
Since final enrolment of surgical patients with diabetes mellitus (DM) has not been established yet, this study is going on under enrolment in targeting number of 150 patients, and further enrolment of patients is mandatory to complete this study. However, we conducted retrospective large study to examine usability, blood glucose measurements, and glycemic control characteristics of novel artificial pancreas (AP) (STG-55) and conventional AP (STG-22). As a result, perioperative intensive insulin therapy (IIT) using an AP in 305 patients with or without DM can be used to prevent hypoglycemia and maintain stable glycemic control with less variability of blood glucose concentration. The usability, performance with respect to blood glucose measurement, and glycemic control characteristics of IIT were comparable between novel and conventional AP systems.Also STG-55 was easier to manipulate than STG-22 due to its smaller size, lower weight, and shorter time for preparation.
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