| Project/Area Number |
23592033
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Nagoya University |
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Principal Investigator |
USUI Akihiko 名古屋大学, 医学(系)研究科(研究院), 教授 (30283443)
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| Co-Investigator(Kenkyū-buntansha) |
OSHIMA Hideki 名古屋大学, 医学部附属病院, 講師 (40378188)
ARAKI Yoshimori 名古屋大学, 医学部附属病院, 病院講師 (70437010)
MUTSUGA Masato 名古屋大学, 医学系研究科, 特任助教 (80447820)
TOKUDA Yoshiyuki 名古屋大学, 医学部附属病院, 病院助教 (30467302)
UEDA Yuichi 名古屋大学, 医学系研究科, 教授 (80314011)
OKADA Masaho 名古屋大学, 医学部附属病院, 助教 (20566989)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 心筋梗塞 / 心室中隔穿孔 / カテーテル治療 / 心臓手術 |
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| Research Abstract |
We developed a catheter therapy for ventricular septum perforation (VSP) by using a stent-graft placed in the left ventricle. we adapt a net type stent which is knitted by a Nytinol thread. As an initial model, we made a cone-shaped stent-graft but it did not fit with papillary muscles. We changed the design of the stent-graft as a dissymmetry. It covered only with the septum but a pressure power of the septum side particularly the septum base side was weak even with the improved model.We made delivery sheath for direct insertion via the apex and developed an insertion method by using peal off system. We insert a stent-graft into a rubber heart model by using this delivery system. The stent graft can be inserted via the left ventricle apex and has it as a design preserving the directionality by fixing it in the apex. The design decision of the stent-graft which does not affect cardiac function is difficult and remains in the completion of a trial
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