Development of the new therapy for ischemic cardiomyopathy

• Project/Area Number: 23592042
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Thoracic surgery
• Research Institution: Kyushu University
• Principal Investigator: NISHIDA TAKAHIRO 九州大学, 医学(系)研究科(研究院), 講師 (50284500)
• Co-Investigator(Kenkyū-buntansha): TANOUE Yoshihisa 九州大学, 大学病院, 講師 (40372742) ; SONODA Hiromichi 九州大学, 医学(系)研究科(研究院), 助教 (50596830) ; OISHI Yasuhisa 九州大学, 大学病院, 助教 (20529870)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 末梢血単核球移植 / アフェレーシス

Research Abstract

The purpose of the present study was to investigate the progress the new therapy against the ischemic cardiomyopathy, we tried to obtain the MNCs from the pig. However it was not possible due to failing the large amount MNCs, We tested the effect of small amount of MNCs to the ischemic limbs of rabbit. Unfortunately. This try was not effective to reduce the limb ischemia.
We recognized that some cells producing the vascular growth factor are mandatory to improve the perfusion of the ischemic organs.