| Project/Area Number |
23592045
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Thoracic surgery
|
|---|
| Research Institution | Yokohama City University |
|---|
Principal Investigator |
MASUDA MUNETAKA 横浜市立大学, 医学(系)研究科(研究院), 教授 (10190365)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MATSUMOTO Naomichi 横浜市立大学, 医学研究科, 教授 (80325638)
SUZUKI Shinichi 横浜市立大学, 医学部, 准教授 (90285130)
IMOTO Kiyotaka 横浜市立大学, 市民総合医療センター, 教授 (40203335)
UCHIDA Keiji 横浜市立大学, 市民総合医療センター, 准教授 (50275062)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
|
|---|
| Keywords | 責任遺伝子 / 大動脈瘤発生 / 早期手術及び予防 / 大動脈瘤 / 遺伝子解析 / シーケンス |
|---|
| Research Abstract |
This study analyzes the abnormality of the responsibility gene cluster of the Mendel hereditary disease to bring about a dissociative aortic aneurysm and a genuine aortic aneurysm with high probability and is intended that I clarify a genotype and the love poem of clinical manifestations (canceration, dissociation and cancer explosion). Using this love poem, I switch it to the custom tailoring treatment that they put together in the risk that the genotype of individual cases shows the decision of the treatment policy to, and I establish the adaptation of the operation in the early stage that is low aggressions such as the stent graft interpolation art, and the death rate is high, and medical expenses aim at the evasion of the large amount of emergency surgery. In addition, I examine the clinical effects such as angiotensin receptor repressors and am intended to contribute to medical expenses reduction.
|
