| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Research Abstract |
If we would protect glioma cell invasion and gather one part, we could threat them more effective. After proteoglycan artificial matrix with molecular target medicine AG1478 were completed, tumor cells were absorbed in artificial matrix. After that, when radiotherapy was done, tumor cell would be killed effectively. In vitro experiment, the optimal concentration of artificial matrix and AG1478 were 15mM and 20mM respectively. The optimal radiation dose was 5Gy. We could confirm tumor cell were treated effectively in pathological findings. Survival analysis was better survival of the radiation group with artificial matrix than of radiation group without artificial matrix. Statistical analysis was significant different. Average of survival were 65 days and 87days respectively.
|
