| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
ARF-BP1 was expressed in parts of glioma tissues, and glioma-derived cell lines in each levels. But there was no relationship between ARF-BP1 expression and the histological differentiation, the histological malignancy, the status of p53 gene mutation, or the status of mdm2 expression of glioma. ARF-BP1 was highly and frequently expressed in germ cell tumors, especially in Germinoma. ARF-BP1 seems to be one of the key molecules in the pathogenesis of germ cell tumors in the brain.
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