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Development of the treatment for meniscal tear with a novel biocompatible adhesive and plasma surface treatment.

Research Project

Project/Area Number 23592186
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionShimane University

Principal Investigator

UCHIO Yuji  島根大学, 医学部, 教授 (20223547)

Co-Investigator(Kenkyū-buntansha) TAGUCHI Tetsushi  独立行政法人物資, 材料研究機構・生体機能材料ユニット, MANA研究者 (70354264)
Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords半月板損傷治療 / 生体接着剤 / プラズマ表面処理 / 半月板損傷 / 半月板 / プラズマ / 半月板断裂
Outline of Final Research Achievements

There is no available treatment for meniscal tear of an avascular zone. To resolve this issue, we devised new technique with the novel adhesive (DST-HAS) and plasma surface treatment, and investigated the effectiveness of this technique.
In conclusion, DST-HSA adhesive may be available material to treat a meniscal tear in an avascular zone. Under the condition of this study, on the other hand, plasma surface treatment had no effectiveness to enhance the adhesion strength of DST-HSA. However, we believe that the study of the plasma surface treatment for meniscal repair should be continued because it has a possibility of becoming an available technique to treat the meniscal tear depending on the condition.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (3 results)

All 2012 2011

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (1 results)

  • [Journal Article] Effectiveness and biocompatibility of a novel biological adhesive application for repair of meniscal tear on the avascular zone2012

    • Author(s)
      Takahito Inoue, Tetsushi Taguchi, Shinji Imade, Nobuyuki Kumahashi and Yuji Uchio
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 13

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 生体接着剤を用いた半月板無血行野断裂修復法の力学的効果2011

    • Author(s)
      井上尊人、田口哲志、熊橋伸之、桑田卓、内尾祐司
    • Journal Title

      日本整形外科學會雑誌

      Volume: 85巻

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] 生体接着剤を用いた半月板無血行野断裂修復法の力学的効果2011

    • Author(s)
      井上尊人、田口哲志、熊橋伸之、桑田卓、内尾祐司
    • Organizer
      第26回日本整形外科学会基礎学術集会
    • Place of Presentation
      ベイシア文化ホール(前橋市)
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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