| Project/Area Number |
23592199
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Keio University |
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Principal Investigator |
ISHII KEN 慶應義塾大学, 医学部, 講師 (00276289)
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| Co-Investigator(Kenkyū-buntansha) |
MATSUMOTO Morio 慶應義塾大学, 医学部, 准教授 (40209656)
SHIONO Yuta 国際医療福祉大学, 大学病院, その他 (60445228)
KURAMOTO Tetsuya 慶應義塾大学, 医学部, 助教 (70445302)
YOSHIOKA Kenji 慶應義塾大学, 医学部, 助教 (30528857)
ISHIHAMA Hiroko 慶應義塾大学, 医学部, 助教 (90528308)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 感染症 / 整形外科学 / 細菌 / イメージング / 抗菌 / DDS / 抗菌インプラント / 分子標的治療 / 整形外科 / 感染 / 生体材料 |
|---|
| Research Abstract |
We have established a real-time, quantitative and reproducible mouse models of staphylococcal osteomyelitis and soft tissue infection using bioluminescence imaging.
We have also developed a new antibacterial implant and drug delivery system for orthopaedic infectious diseases. Based on the results from our research, we have now moved on the preparation of clinical trial using these techniques.
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