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Development of a fiber-optic intravenous catheter system for continuous blood glucose concentration monitoring

Research Project

Project/Area Number 23592282
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Anesthesiology/Resuscitation studies
Research InstitutionHamamatsu University School of Medicine

Principal Investigator

DOI MATSUYUKI  浜松医科大学, 医学部附属病院, 准教授 (10155616)

Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords光技術 / 血中濃度測定 / ブドウ糖 / 光テクノロジー / ブドウ糖濃度測定
Outline of Final Research Achievements

The aim of this study was to develop a fiber-optic intravenous catheter system for continuous blood glucose concentration monitoring. We investigated materials as blood glucose sensor to be mounted on the tip of the catheter. We found anthracene-phenyl-diboronic acid was suitable as the sensor. It emitted 430 nm fluorescence with 370 nm excitation light. The intensity of the fluorescence depended on glucose concentration up to 400 mg/dl, but gradually diminished beyond 12 hours monitoring time. Anthracene-phenyl-diboronic acid was one of promising glucose sensors, but required improvement of long time sutability.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (4 results)

All 2014

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (2 results)

  • [Journal Article] レミマゾラム2014

    • Author(s)
      土井松幸
    • Journal Title

      日本臨床麻酔学会誌

      Volume: 34 Pages: 860-866

    • NAID

      130004892958

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Safety and efficacy of dexmedetomidine for long-term sedation in critically ill patints.2014

    • Author(s)
      Ozaki M, Doi M
    • Journal Title

      Journal of Anesthesia

      Volume: 28 Pages: 38-50

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] マイクロダイアライシス法を用いた出血モデルラットにおけるNO2,NO3の変化の検討.2014

    • Author(s)
      御室総一郎,土井 松幸, 加藤孝澄,佐藤 重仁,吉見美生
    • Organizer
      日本蘇生学会第33回大会
    • Place of Presentation
      静岡県浜松市
    • Year and Date
      2014-12-06
    • Related Report
      2014 Annual Research Report
  • [Presentation] 心臓血管麻酔後の集中治療管理のエビデンスと工夫2014

    • Author(s)
      土井松幸
    • Organizer
      日本心臓血管麻酔科学会第61回大会
    • Place of Presentation
      大阪府吹田市
    • Year and Date
      2014-09-21
    • Related Report
      2014 Annual Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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