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The effects of Waon therapy on neuropathic pain.

Research Project

Project/Area Number 23592296
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Anesthesiology/Resuscitation studies
Research InstitutionKyushu University

Principal Investigator

SUMIO Hoka  九州大学, 医学(系)研究科(研究院), 教授 (60150447)

Co-Investigator(Kenkyū-buntansha) 鄭 忠和  鹿児島大学, 医歯(薬)学総合研究科, 教授 (10163891)
山浦 健  九州大学病院, 准教授 (70264041)
塩川 浩輝  九州大学, 医学研究院, 助教 (30572490)
大庭 由宇吾  九州大学病院, 助教 (30567368)
Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords慢性痛 / 和温療法 / 神経障害性疼痛 / 心理的アプローチ / 抑うつ / 不安 / 慢性疼痛 / 心理社会的因子 / 疼痛治療 / ペインクリニック / 漢方薬 / 複合性局所疼痛症候群
Outline of Final Research Achievements

The effects of Waon therapy were examined in patients with chronic neuropathic pain. The maximum observation period was 27 months. There were no significant differences between Visual Analogue Scales before and after Waon therapy. Since pain produces negative emotions such as anxiety and depression, we examined the influence of neuropathic pain on the negative emotion and thinking. The scales of depression and anxiety were significantly higher in patients with neuropathic pain than those without neuropathic pain. These results suggest that Waon therapy may not be effective in patients with chronic severe neuropathic pain by itself and that patients with neuropathic pain are more related to negative emotion and thinking. Thus it is also suggested that Waon therapy can be effective if psychological approach is taken into consideration for pain management.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (36 results)

All 2015 2014 2013 2012 2011

All Journal Article (11 results) (of which Peer Reviewed: 7 results,  Open Access: 4 results) Presentation (20 results) (of which Invited: 2 results) Book (5 results)

  • [Journal Article] In-line pressure within a HOTLINE(®) Fluid Warmer, under various flow conditions.2015

    • Author(s)
      Higashi M, Yamaura K, Matsubara Y, Fukudome T, Hoka S.
    • Journal Title

      J Clin Monit Comput

      Volume: 29 Issue: 2 Pages: 301-5

    • DOI

      10.1007/s10877-014-9605-3

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] C-C chemokine receptor type 5 is an important pathological regulator in the development and maintenance of neuropathic pain.2014

    • Author(s)
      K. Matsushita, C. Kojima, H. Tozaki-Saitoh, M. Tsuda, K. Inoue, S. Hoka.
    • Journal Title

      Anesthesiology

      Volume: 印刷中 Issue: 6 Pages: 1491-503

    • DOI

      10.1097/aln.0000000000000190

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of thermoregulatory vasoconstriction on pulse hemoglobin measurements using a co-oximeter in patients undergoing surgery.2014

    • Author(s)
      Yamaura K, Nanishi N, Higashi M, Hoka S.
    • Journal Title

      J Clin Anesth

      Volume: 26 Issue: 8 Pages: 643-7

    • DOI

      10.1016/j.jclinane.2014.04.012

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 痛みの声を聴く2014

    • Author(s)
      外 須美夫
    • Journal Title

      慢性疼痛

      Volume: 33 Pages: 21-26

    • Related Report
      2014 Annual Research Report
    • Open Access
  • [Journal Article] Diastolic function of the left ventricle is associated with pulmonary edema after renal transplantation2013

    • Author(s)
      Higashi M, Yamaura K, Ikeda M, Shimauchi T, Saiki H, Hoka S
    • Journal Title

      Acta Anaesthesiol Scand

      Volume: 121 Issue: 9 Pages: 1154-1160

    • DOI

      10.1111/aas.12168

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 術後疼痛コントロール2012

    • Author(s)
      辛島裕士、外 須美夫
    • Journal Title

      臨床と研究

      Volume: 89 Pages: 66-70

    • Related Report
      2012 Research-status Report
  • [Journal Article] The utility of muscle sparing axillar skin crease incision for pediatric thoracic surgery.2012

    • Author(s)
      Taguchi T, Nagata K, Kinoshita Y, Ieiri S, Tajiri T, Teshiba R, Esumi G, Karashima Y, Hoka S, Masumoto K.
    • Journal Title

      Pediatr Surg Int.

      Volume: 28 Pages: 239-44

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Neurotoxicity of intrathecally administered fentanyl in a rat spinal model.2011

    • Author(s)
      Fukushima S, Takenami T, Yagishita S, Nara Y, Hoka S, Okamoto H
    • Journal Title

      Pain Med

      Volume: 12 Pages: 717-25

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Accuracy of arterial pressure waveform analysis for cardiac output measurement in comparison with thermodilution methods in patients undergoing living donor liver transplantation.2011

    • Author(s)
      Akiyoshi K, Kandabashi T, Kaji J, Yamaura K, Yoshimura H, Irita K, Hoka S.
    • Journal Title

      J Anesth

      Volume: 25 Pages: 178-83

    • NAID

      10029022289

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 感覚とTRPチャネル2011

    • Author(s)
      辛島 裕士、外 須美夫
    • Journal Title

      福岡医学雑誌

      Volume: 102 Pages: 48-55

    • NAID

      120003043290

    • Related Report
      2011 Research-status Report
  • [Journal Article] 慢性疼痛へのアプローチ、EBMとガイドライン2011

    • Author(s)
      大庭由宇吾、外 須美夫
    • Journal Title

      総合リハビリテーション

      Volume: 39 Pages: 739-44

    • Related Report
      2011 Research-status Report
  • [Presentation] Influence of two different pain components on negative emotion and thinking in chronic pain patients2014

    • Author(s)
      Hiroaki Shiokawa, Yugo Oba, Yoshimasa Motoyama and Sumio Hoka
    • Organizer
      15th World Congress on Pain
    • Place of Presentation
      ブエノスアイレス
    • Year and Date
      2014-10-06 – 2014-10-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] トリガーポイント注射とリハビリ療法により症状の完全消失を認めた小児CRPSの一例2014

    • Author(s)
      石邉 奈津紀, 塩川 浩輝, 大庭 由宇吾, 本山 嘉正, 甲斐 哲也, 外 須美夫
    • Organizer
      日本ペインクリニック学会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-24 – 2014-07-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 硬膜外自家血パッチ施行後に下肢麻痺を生じた一症例(第二報)2014

    • Author(s)
      本山嘉正、大庭由宇吾、塩川浩輝、甲斐哲也、外須美夫
    • Organizer
      日本ペインクリニック学会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-24 – 2014-07-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] Direct actions of Ultiva® on dorsal horn neurons in the rat spinal cord revealed by patch clamp analysis2014

    • Author(s)
      Sumie M, Shiokawa H, Karashima Y, Yamaura K, Hoka S, Yoshimura M
    • Organizer
      Euroanaeshtesia
    • Place of Presentation
      カロリンスカ
    • Year and Date
      2014-06-02 – 2014-06-04
    • Related Report
      2014 Annual Research Report
  • [Presentation] ラットの脊髄後角に対するアルチバの直接作用の検討2014

    • Author(s)
      住江 誠、塩川 浩輝、山浦 健、辛島 裕士、外 須美夫、吉村 恵
    • Organizer
      日本麻酔科学会第61回学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-05-15 – 2014-05-17
    • Related Report
      2014 Annual Research Report
  • [Presentation] 痛みの性状と心理状態(不安、抑うつ、破局的思考)との関連性の検討2014

    • Author(s)
      大庭 由宇吾、 塩川 浩輝、 波多野 有美、 木村 めぐみ、 甲斐 哲也、 外 須美夫
    • Organizer
      日本麻酔科学会第61回学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-05-15 – 2014-05-17
    • Related Report
      2014 Annual Research Report
  • [Presentation] 痛みの声を聴く2014

    • Author(s)
      外 須美夫
    • Organizer
      日本慢性疼痛学会
    • Place of Presentation
      横浜
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] A magnetoencephalography study on pain-relief by vibrotactile stimulation2013

    • Author(s)
      Hayamizu M, Hagaiwara K, Hironaga N, Ogata K, Hoka S, Tobimatsu S
    • Organizer
      European Pain Federation EFIC
    • Place of Presentation
      Florence, Italy
    • Related Report
      2013 Research-status Report
  • [Presentation] C-Cchemokine receptor type 5 is an important regulator in the development and maintenance of neuropathic pain2013

    • Author(s)
      Matsushita K, Tozaki-Satoh, Tsuda M, Inoue K, Hoka S
    • Organizer
      American Society of Anesthesiologists
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] Evaluation of analgesic and hypnotic effects of remifentanil by in vivo patch-clamp recordings2013

    • Author(s)
      Shiokawa H, Yamaura K, Karashima Y, Hoka S, Yoshimura M
    • Organizer
      European Society of Anesthesiology
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2013 Research-status Report
  • [Presentation] 麻酔の過去・現在・未来2012

    • Author(s)
      外 須美夫
    • Organizer
      第40回日本歯科麻酔学会
    • Place of Presentation
      福岡
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Evaluation of analgesic and hypnotic effects of pentobarbital and proposal usin in vivo patch clamp recording from rat somatosensory cortex.2012

    • Author(s)
      Shiokawa H, Yamaura K, Karashima Y, Hoka S, Yoshimura M
    • Organizer
      Annual meeting of American Society of Anesthesiologists
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] 本人と母親への心理的サポートとリハビリ療法により劇的な症状改善を認めた左下肢CRPSの一例2012

    • Author(s)
      塩川浩輝、細井昌子、原正文、大庭由宇吾、安野広三、河田浩、外 須美夫
    • Organizer
      日本慢性疼痛学会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Presentation] ペインクリニック外来受診を景気に診断された他科疾患の3症例2012

    • Author(s)
      松下克之、大庭由宇吾、甲斐哲也、塩川浩輝、早水真理子、外 須美夫
    • Organizer
      日本ペインクリニック学会
    • Place of Presentation
      松江
    • Related Report
      2012 Research-status Report
  • [Presentation] Neural substrates of empathy for pain: A neurophysiological study2011

    • Author(s)
      Motoyama Y, Ogata K, Hoka S, Tobimatsu S
    • Organizer
      Annual Meeting of the American Society of Anesthesiologists
    • Place of Presentation
      Chicago, USA
    • Related Report
      2011 Research-status Report
  • [Presentation] Bimodal action of propofol on TRPA12011

    • Author(s)
      Karashima Y, Hoka S
    • Organizer
      European Society of Anaesthesiology Annual Meeting, Euroanaestehsia 2011
    • Place of Presentation
      Amsterdam, Netherlands
    • Related Report
      2011 Research-status Report
  • [Presentation] Cultural considerations for meaning of pain: the Japanese versus the West2011

    • Author(s)
      Hoka S
    • Organizer
      Interdisciplinary & Internatinal Pain & Suffering Workshop(招待講演)
    • Place of Presentation
      Luxembourg
    • Related Report
      2011 Research-status Report
  • [Presentation] 動眼神経麻痺を来した三叉神経第1枝・第2枝領域帯状疱疹の1症例2011

    • Author(s)
      大庭由宇吾、塩川浩輝、福元智子、外 須美夫
    • Organizer
      日本ペインクリニック学会
    • Place of Presentation
      松山市
    • Related Report
      2011 Research-status Report
  • [Presentation] 術前肺機能検査の意義、麻酔と肺機能2011

    • Author(s)
      外 須美夫
    • Organizer
      九州肺機能談話会(招待講演)
    • Place of Presentation
      鹿児島市
    • Related Report
      2011 Research-status Report
  • [Presentation] ラット脊髄後角深層におけるドパミンD1様受容体による抑制性伝達の増強2011

    • Author(s)
      大庭由宇吾、片淵俊彦、塩川浩輝、前田愛子、吉村恵、外 須美夫
    • Organizer
      日本麻酔科学会
    • Place of Presentation
      神戸市
    • Related Report
      2011 Research-status Report
  • [Book] 麻酔はなぜ効くのか?痛みの哲学臨床ノート2013

    • Author(s)
      外 須美夫
    • Total Pages
      247
    • Publisher
      春秋社
    • Related Report
      2013 Research-status Report
  • [Book] 特集「痛みの声を聴け」2013

    • Author(s)
      外 須美夫
    • Total Pages
      86
    • Publisher
      たばこ総合研究センター
    • Related Report
      2013 Research-status Report
  • [Book] 痛みのSAcience&Practice 第1巻(手術後鎮痛のすべて)2013

    • Author(s)
      塩川浩輝、外 須美夫
    • Publisher
      文光堂
    • Related Report
      2013 Research-status Report
  • [Book] 君も麻酔科医にならないか2012

    • Author(s)
      外 須美夫
    • Total Pages
      194
    • Publisher
      真興交易遺書出版部
    • Related Report
      2012 Research-status Report
  • [Book] 麻酔・集中治療のための呼吸・循環のダイナミズム2011

    • Author(s)
      外 須美夫
    • Total Pages
      312
    • Publisher
      真興交易医書出版部
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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