| Project/Area Number |
23592421
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | St. Marianna University School of Medicine |
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Principal Investigator |
SUZUKI Nao 聖マリアンナ医科大学, 医学部, 教授 (90246356)
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| Co-Investigator(Kenkyū-buntansha) |
ISHIZUKA Bunpei 聖マリアンナ医科大学, 医学部, 教授 (80097336)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 卵巣組織凍結 / ガラス化法 / 若年女性がん患者 / 卵巣組織凍結用デバイス |
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| Research Abstract |
The effectiveness of cryopreservation for the primordial follicles in the ovarian tissue and the safety of an open-type device of ovarian tissue cryopreservation using vitrificaton technique should be necessary to evaluate as a new technology of ovarian tissue cryopreservation. On the other hand, there is no method to evaluate the success or failure of the ovarian tissue transplantation, and, as for clarifying the distribution of a new blood vessel flowing into the transplant ovarian tissues, it can be with information important at all.
In this study, we succeeded to prepare the closed-type device of ovarian tissue cryopreservation using vitrificaton technique that assumed a polymeric film and, on the other hand, evaluated the effectiveness of cryopreservation for the primordial follicles in the ovarian tissue using Rapid-i kit. Furthermore, we succeeded in catching a re-inflow of the bloodstream by echo-wave video diagnosis with the rat fresh ovary.
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