Research the regulators, including cytokine, of intratumoral biosynthesis of estrogen in endometrial cancer microenvironment

• Project/Area Number: 23592431
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Obstetrics and gynecology
• Research Institution: Tohoku University
• Principal Investigator: ITO Kiyoshi 東北大学, 災害科学国際研究所, 教授 (70241594)
• Co-Investigator(Kenkyū-buntansha): SUZUKI Takashi 東北大学, 医学(系)研究科(研究院), 教授 (10261629) ; YOSHINAGA Kousuke 東北大学, 医学(系)研究科(研究院), 非常勤講師 (40343058)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 癌―間質相互作用 / 子宮内膜癌 / intracrinology / estrogen / testosterone / steroid sulfatase / 子宮内膜異型増殖症 / LC-MS/MS法 / Intracrinology / Estrogen / Testosterone / 5α-dihydrotestosterone / CRH / Androstenedione

Research Abstract

Intratumoral concentrations of sex-steroid hormone and stress hormone were
elevated in the endometrial carcinoma. On the other hand, we indicated steroid sulfatase played a very
important role in the local biosynthesis of estrogen in human endometrial cancer through tumor-stromal cell interactions. Therefore, steroid sulfatase inhibitors should be useful drugs especially for patients with endometrial cancers, which have steroid sulfatase activities.

Research Products

• [Journal Article] 子宮癌肉腫における術前内膜細胞診の意義 (2014)
  • Author(s): 志賀尚美、岡本聡、海法道子、宇都宮裕貴、永瀬智、高野忠夫、新倉仁、伊藤潔、八重樫伸生
  • Volume: 53(1)
  • Pages: 7-12
  • NAID: 130004513225
  • Peer Reviewed
• [Journal Article] Clinical outcome of pelvic exenteration in patients with advanced or recurrent uterine cervical cancer. (2014)
  • Author(s): Tanaka S, Nagase S, Kaiho-Sakuma M, Nagai T, Kurosawa H, Toyoshima M, Tokunaga H, Otsuki T, Utsunomiya H, Takano T, Niikura H, Ito K, Yaegashi N.
  • Journal Title: Int J Clin Oncol Volume: 19 Issue: 1 Pages: 133-138
  • DOI: 10.1007/s10147-013-0534-9
  • Peer Reviewed
• [Journal Article] Small cell carcinoma of the uterine cervix : clinical outcome of concurrent chemoradiotherapy with a multidrug regimen (2013)
  • Author(s): Tokunaga H, Nagase S, Yoshinaga K, Tanaka S, Nagai T, Kurosawa H, Kaiho-Sakuma M, Toyoshima M, Otsuki T, Utsunomiya H, Takano T, Niikura H, Ito K, Yaegashi N
  • Journal Title: Tohoku J Exp Med Volume: 229(1) Pages: 75-81
  • NAID: 10031143090
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/23269283
  • Peer Reviewed
• [Journal Article] Expression of steroid and xenobiotic receptor in uterine carcinosarcoma, leiomyosarcoma and endometrial stromal sarcoma (2013)
  • Author(s): Yue X, Utsunomiya H, Akahira JI, Suzuki F, Ito K, Nagase S, Sasano H, Yaegashi N
  • Journal Title: Oncol Lett Volume: 5(3) Pages: 835-839
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/23443531
  • Peer Reviewed
• [Journal Article] Tracer injection sites and combinations for sentinel lymph node detection in patients with endometrial cancer. (2013)
  • Author(s): Niikura H, Kaiho-Sakuma M, Tokunaga H, Toyoshima M, Utsunomiya H, Nagase S, Takano T, Watanabe M, Ito K, Yaegashi N
  • Journal Title: Gynecol Oncol. Volume: 131 Issue: 2 Pages: 299-303
  • DOI: 10.1016/j.ygyno.2013.08.018
  • Peer Reviewed
• [Journal Article] Feasibility study of gemcitabine plus docetaxel in advanced or recurrent uterine leiomyosarcoma and undifferentiated endometrial sarcoma in Japan (2013)
  • Author(s): Takano T, Niikura H, Ito K, Nagase S, Utsunomiya H, Otsuki T, Toyoshima M, Tokunaga H, Kaiho-Sakuma M, Shiga N, Nagai T, Tanaka S, Otsuki A, Kurosawa H, Shigeta S, Tsuji K, Yamaguchi T, Yaegashi N
  • Journal Title: Int J Clin Oncol Volume: (Epub ahead of print)
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/24149774
  • Peer Reviewed
• [Journal Article] Decreased expression of 14-3-3σis predictive of poor prognosis for patients with human uterine papillary serous carcinoma (2013)
  • Author(s): Suzuki F, Nagase S, Suzuki K, Oba E, Hiroki E, Matsuda Y, Akahira J, Nishigori H, Sugiyama T, Otsuki T, Yoshinaga K, Takano T, Niikura H, Ito K, Sasano H, Yaegashi N
  • Journal Title: Tohoku J Exp Med Volume: 231(3) Pages: 193-199
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/24201220
  • Peer Reviewed
• [Journal Article] 子宮体癌術後のホルモン補充療法(HRT)に関する知見 (2013)
  • Author(s): 伊藤潔
  • Journal Title: 第11回婦人科悪性腫瘍研究機構年次会議(総会)記録集 Volume: 11 Pages: 197-204
• [Journal Article] 乳がんと性ステロイド合成阻害剤:現状と将来 (2013)
  • Author(s): 三木康宏、笹野公伸、伊藤潔
  • Journal Title: 産婦人科の実際 Volume: 62 Pages: 1247-1253
• [Journal Article] 子宮体がんと性ステロイド合成阻害剤 (2013)
  • Author(s): 宇都宮裕貴、伊藤潔、志賀尚美、辻圭太、西本光男、八重樫伸生
  • Journal Title: 産婦人科の実際 Volume: 62 Pages: 1201-1206
• [Journal Article] 企画者のことば(特集:ホルモン依存性悪性腫瘍―特徴と対処を考える) (2013)
  • Author(s): 伊藤潔
  • Journal Title: 産婦人科の実際 Volume: 62 Pages: 1166-1166
• [Journal Article] 卵巣癌 (2013)
  • Author(s): 海法道子、伊藤潔
  • Journal Title: Modern Physician Volume: 33 Pages: 327-330
• [Journal Article] Small cell carcinoma of the uterine cervix: clinical outcome of concurrent chemoradiotherapy with a multidrug regimen. (2013)
  • Author(s): Tokunaga H, Nagase S, Yoshinaga K, Tanaka S, Nagai T, Kurosawa H, Kaiho-Sakuma M, Toyoshima M, Otsuki T, Utsunomiya H, Takano T, Niikura H, Ito K, Yaegashi N.
  • Journal Title: Tohoku J Exp Med. Volume: 229(1) Pages: 75-81
  • NAID: 10031143090
  • Peer Reviewed
• [Journal Article] Expression of steroid and xenobiotic receptor in uterine carcinosarcoma, leiomyosarcoma and endometrial stromal sarcoma. (2013)
  • Author(s): Yue X, Utsunomiya H, Akahira JI, Suzuki F, Ito K, Nagase S, Sasano H, Yaegashi N
  • Journal Title: Oncol Lett. Volume: 5(3) Pages: 835-839
  • Peer Reviewed
• [Journal Article] Feasibility study of gemcitabine plus docetaxel in advanced or recurrent uterine leiomyosarcoma and undifferentiated endometrial sarcoma in Japan. (2013)
  • Author(s): Takano T, Niikura H, Ito K, Nagase S, Utsunomiya H, Otsuki T, Toyoshima M, Tokunaga H, Kaiho-Sakuma M, Shiga N, Nagai T, Tanaka S, Otsuki A, Kurosawa H, Shigeta S, Tsuji K, Yamaguchi T, Yaegashi N.
  • Journal Title: Int J Clin Oncol. Volume: 2013Oct24[Epub ahead of print]
  • Peer Reviewed
• [Journal Article] Decreased expression of 14-3-3σ is predictive of poor prognosis for patients with human uterine papillary serous carcinoma. (2013)
  • Author(s): Suzuki F, Nagase S, Suzuki K, Oba E, Hiroki E, Matsuda Y, Akahira J, Nishigori H, Sugiyama T, Otsuki T, Yoshinaga K, Takano T, Niikura H, Ito K, Sasano H, Yaegashi N.
  • Journal Title: Tohoku J Exp Med. Volume: 231(3) Pages: 193-9
  • NAID: 130004720755
  • Peer Reviewed
• [Journal Article] 子宮体癌術後のホルモン補充療法（HRT)に関する知見 (2013)
  • Author(s): 伊藤潔
  • Journal Title: 第11回婦人科悪性腫瘍研究機構年次会議(総会)記録集 Volume: １１ Pages: 197-204
• [Journal Article] 乳がんと性ステロイド合成阻害剤：現状と将来 (2013)
  • Author(s): 三木康宏、笹野公伸、伊藤潔
  • Journal Title: 産婦人科の実際 Volume: 62 Pages: 1247-1253
• [Journal Article] 企画者のことば(特集：ホルモン依存性悪性腫瘍―特徴と対処を考える） (2013)
  • Author(s): 伊藤 潔
  • Journal Title: 産婦人科の実際 Volume: 62 Pages: 1166-1166
• [Journal Article] 子宮癌肉腫における術前内膜細胞診の意義 (2013)
  • Author(s): 志賀尚美、岡本聡、海法道子、宇都宮裕貴、永瀬智、高野忠夫、新倉仁、伊藤潔、八重樫伸生
  • Journal Title: J.Jpn.Soc.Clin.Cytol 2014 Volume: 53(1) Pages: 7-12
  • NAID: 130004513225
  • Peer Reviewed
• [Journal Article] Prospective study of sentinel lymph node biopsy without further pelvic lymphadenectomy in patients with sentinel lymph node-negative cervical cancer (2012)
  • Author(s): Niikura H, Okamoto S, Otsuki T, Yoshinaga K, Utsunomiya H, Nagase S, Takano T, Ito K, Watanabe M,Yaegashi N
  • Journal Title: Int J Gynecol Cancer Volume: 22(7) Issue: 7 Pages: 1244-1250
  • DOI: 10.1097/igc.0b013e318263f06a
  • Peer Reviewed
• [Journal Article] Individualized radical hysterectomy procedure using intraoperative electricalstimulation for patientswith cervical cancer (2012)
  • Author(s): Nagai T, Niikura H, Kurosawa H, Tanaka S, Otsuki T, Utunomiya H, Nagase S, Takano T, Ito K, Kaiho Y, Nakagawa H, Arai Y, Yaegashi N
  • Journal Title: Int J Gynecol Cancer Volume: 22(9) Issue: 9 Pages: 1591-1596
  • DOI: 10.1097/igc.0b013e31826fd684
  • Peer Reviewed
• [Journal Article] Multidisciplinary approach to a case of Lynch syndrome with colorectal, ovarian, and metastatic liver carcinomas (2012)
  • Author(s): Shiono M, Shimodaira H, Watanabe M, Takase K, Ito K, Miura K, Takami Y, Akiyama S, Kakudo Y, Takahashi S, Takahashi M, Ishioka C
  • Journal Title: Int Canc Conf J Volume: 1 Pages: 125-137
  • Peer Reviewed
• [Journal Article] Hysteroscopic Inspection and Total Curettage Are Insufficient for Discriminating Endometrial Cancer from Atypical Endometrial Hyperplasia (2012)
  • Author(s): Kurosawa H, Ito K, Nikura H, Takano T, Nagase S, Utsunomiya H, Otsuki T, Toyoshima M, Nagai T, Tanaka S, Watanabe M, Yaegashi N
  • Journal Title: Tohoku J Exp Med Volume: 228 Pages: 365-370
  • NAID: 10031135562
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/23154663
  • Peer Reviewed
• [Journal Article] MicroRNA-34b functions as a potential tumor suppressor in endometrial serous adenocarcinoma (2012)
  • Author(s): Hiroki E, Akahira J, et al
  • Journal Title: Int J Cancer Volume: (印刷中) Issue: 4 Pages: 395-404
  • DOI: 10.1002/ijc.27345
  • Peer Reviewed
• [Journal Article] Reply to Comments on "Inhibition of estrogen actions in human gynecological malignancies: New aspects of endocrine therapy for endometrial cancer and ovarian cancer". (2012)
  • Author(s): Ito K, Utsunomiya H, Niikura H, Yaegashi N, Sasano H.
  • Journal Title: Mol Cell Endocrinol. Volume: 363 Issue: 1-2 Pages: 133-133
  • DOI: 10.1016/j.mce.2011.08.024
  • Peer Reviewed
• [Journal Article] Guidelines for office gynecology in Japan : Japan Society of Obstetrics and Gynecology and Japan Association of Obstetricians and Gynecologists 2011 edition (2012)
  • Author(s): Takeda T, Wong TF, Adachi T, Ito K, Uehara S, Kanaoka Y, Kamada M, Kitagawa H, Koseki S, Gomibuchi H, Saito J, Shirasu K, Sueoka K, Sugimoto M, Suzuki M, Sumi T, Takeda S, Tasaka K, Noguchi Y, Fujii S, Fujii T, Fujiwara M, Maeda T, Matsumoto K, Momoeda M, Morita M, Yoshimura K, Hirai Y, Kubota T, Sakuragi N, Kawabata M, Yoshikawa H, Kobayashi H, Yaegashi N
  • Journal Title: J Obstet Gynaecol Res Volume: 38 Pages: 615-631
  • Peer Reviewed
• [Journal Article] Hysteroscopic Inspection and Total Curettage Are Insufficient for Discriminating Endometrial Cancer from Atypical Endometrial Hyperplasia (2012)
  • Author(s): Kurosawa H,Ito K*, Niikura H, Takano T, Nagase S, Utsunomiya H, Otsuki T, Toyoshima M, Nagai T, Tanaka S, Watanabe M, Yaegashi N
  • Journal Title: The Tohoku Journal of Experimental Medicine Volume: 228 Issue: 4 Pages: 365-370
  • DOI: 10.1620/tjem.228.365
  • NAID: 10031135562
  • ISSN: 0040-8727, 1349-3329
  • Peer Reviewed
• [Journal Article] Guidelines for office gynecology in Japan: Japan Society of Obstetrics and Gynecology and Japan Association of Obstetricians and Gynecologists 2011 edition. (2012)
  • Author(s): Takeda T.et al.
  • Journal Title: J Obstet Gynaecol Res. Volume: 38 Pages: 615-631
  • Peer Reviewed
• [Journal Article] Reply to Comments on "Inhibition of estrogen actions in human gynecological malignancies: New aspects ofendocrine therapy for endometrial cancer and ovarian cancer" (2011)
  • Author(s): Ito K, Utsunomiya H, Niikura H, Yaegashi N, Sasano H
  • Journal Title: Mol Cell Endocrinol Volume: 340(2) Issue: 2 Pages: 161-7
  • DOI: 10.1016/j.mce.2010.11.023
  • Peer Reviewed
• [Journal Article] Steroid sulfatase and estrogen sulfotransferase in human carcinomas (2011)
  • Author(s): Suzuki T, Miki Y, Nakamura Y, Ito K, Sasano H
  • Journal Title: Mol Cell Endocrinol Volume: 340 Issue: 2 Pages: 148-153
  • DOI: 10.1016/j.mce.2010.11.001
  • Peer Reviewed
• [Journal Article] Roles of intrinsic angiogenesis inhibitor, vasohibin, in cervical carcinomas (2011)
  • Author(s): Yoshinaga K, Ito K, Moriya T, Nagase S, Takano T, Niikura H, Sasano H, Yaegashi N, Sato Y
  • Journal Title: Cancer Sci Volume: 102 Pages: 446-451
  • NAID: 10029290441
  • Peer Reviewed
• [Journal Article] Association of Keap1 and Nrf2 genetic mutations and polymorphisms with endometrioid endometrial adenocarcinoma survival (2011)
  • Author(s): Wong TF, Yoshinaga K, Monma Y, Ito K, Niikura H, Nagase S, Yamamoto M, Yaegashi N
  • Journal Title: Int J Gynecol Cancer Volume: 21 Issue: 8 Pages: 1428-1435
  • DOI: 10.1097/igc.0b013e31822d0eb2
  • Peer Reviewed
• [Journal Article] Reply to Comments on "Inhibition of estrogen actions in human gynecological malignancies: New aspects of endocrine therapy for endometrial cancer and ovarian cancer" (2011)
  • Author(s): Ito K, Utsunomiya H, Niikura H, Yaegashi N, Sasano H.
  • Journal Title: Mol Cell Endocrinol. Volume: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Inhibition of estrogen actions in human gynecological malignancies: New aspects of endocrine therapy for endometrial cancer and ovarian cancer. (2011)
  • Author(s): Ito K, Utsunomiya H, Niikura H, Yaegashi N, Niikura H, Yaegashi N, Sasano H.
  • Journal Title: Mol Cell Endocrinol. Volume: 340 Pages: 161-7
  • Peer Reviewed
• [Journal Article] Steroid sulfatase and estrogen sulfotransferase in human carcinomas. (2011)
  • Author(s): Suzuki T, Miki Y, Nakamura Y, Ito K, Sasano H.
  • Journal Title: Mol Cell Endocrinol. Volume: 340 Pages: 148-53
  • Peer Reviewed
• [Journal Article] Roles of intrinsic angiogenesis inhibitor, vasohibin, in cervical carcinomas. (2011)
  • Author(s): Yoshinaga K, Ito K, Moriya T, Nagase S, Takano T, Niikura H, Sasano H,
  • Journal Title: Cancer Sci. Volume: 102 Pages: 446-51
  • NAID: 10029290441
  • Peer Reviewed
• [Journal Article] Association of keap1 and nrf2 genetic mutations and polymorphisms with endometrioid endometrial Adenocarcinoma survival. (2011)
  • Author(s): Wong TF, Yoshinaga K, Monma Y, Ito K, Niikura H, Nagase S, Yamamoto M, Yaegashi N.
  • Journal Title: Int J Gynecol Cancer. Volume: 21 Pages: 1428-35
  • Peer Reviewed
• [Journal Article] MicroRNA-34b functions as a potential tumor suppressor in endometrial serous adenocarcinoma. (2011)
  • Author(s): Hiroki E, Suzuki F, Akahira JI, Nagase S, Ito K, Sugawara J, Miki Y, Suzuki T, Sasano H, Yaegashi N.
  • Journal Title: Int J Cancer. Volume: Epub ahead of print
  • Peer Reviewed
• [Presentation] 「子宮体がん治療後の患者へのホルモン補充療法(HRT)施行に関するアンケート」調査概要報告 (2013)
  • Author(s): 伊藤潔、高松潔、横山良仁
  • Organizer: 第12回婦人科悪性腫瘍研究機構(JGOG)年次会議(総会)
  • Place of Presentation: 東京
  • Year and Date: 2013-11-29
• [Presentation] ヒト子宮内膜癌におけるCRH発現と予後の関連 (2013)
  • Author(s): 佐藤菜保子、高木清司、鈴木貴、三木康宏、割田仁、福土審、佐藤冨美子八重樫伸生、伊藤潔
  • Organizer: 第51回日本癌治療学会
  • Place of Presentation: 京都
  • Year and Date: 2013-10-25
• [Presentation] 日本人女性における食物摂取と子宮体部類内膜腺癌発症リスクについての症例対照研究 (2013)
  • Author(s): 重田昌吾、永瀬智、高山真、豊島将文、宇都宮裕貴、菅原準一、伊藤潔、八重樫伸生
  • Organizer: 第61回北日本産科婦人科学会学学術講演会.
  • Place of Presentation: 旭川
  • Year and Date: 2013-09-07
• [Presentation] 子宮内膜癌におけるSteroid sulfatase阻害剤の有用性に関する検討 (2013)
  • Author(s): 西本光男、宇都宮裕貴、志賀尚美、海法道子、鈴木史彦、徳永英樹、伊藤潔、八重樫伸生
  • Organizer: 日本産婦人科学会第65回学術講演会
  • Place of Presentation: 旭川
  • Year and Date: 2013-09-07
• [Presentation] 子宮内膜癌におけるSteroid sulfatase阻害剤の有用性に関する検討 (2013)
  • Author(s): 西本光男、宇都宮裕貴、志賀尚美、辻圭太、海法道子、鈴木史彦、徳永英樹、伊藤潔、八重樫伸生
  • Organizer: 日本産婦人科学会第65回学術講演会.
  • Place of Presentation: 札幌
  • Year and Date: 2013-05-10
• [Presentation] 子宮体部漿液性腺癌におけるmicroRNA-34bの癌抑制的な機能の検討 (2013)
  • Author(s): 鈴木史彦、永瀬智、廣木恵理、宇都宮裕貴、伊藤潔、新倉仁、赤平純一、笹野公伸、八重樫伸生
  • Organizer: 日本産婦人科学会第65回学術講演会
  • Place of Presentation: 札幌
  • Year and Date: 2013-05-10
• [Presentation] Intratumoral Concentration of Stress Hormone Cortisol in Endometrial Carcinoma (2013)
  • Author(s): Miki Y, Takagi K, Suzuki T, Ito K
  • Organizer: NIH-Tohoku Universtity-JSPS Symposium
  • Place of Presentation: Sendai, Japan
  • Year and Date: 2013-05-10
• [Presentation] Intratumoral androgen concentrations in endometrial carcinoma tissues (2013)
  • Author(s): Tanaka S, Miki Y, Suzuki T, Zhulanqiqige D, Takagi K, Utsunomiya H, Nagase S, Niikura H, Yaegashi N, Ito K.
  • Organizer: The 18th International Meeting of the European Society of Gynecological Oncology
  • Place of Presentation: Liverpool , England
• [Presentation] 子宮体癌術後のホルモン補充療法(HRT)に関する知見(オープンディスカッション) (2012)
  • Author(s): 伊藤潔,高松潔
  • Organizer: 婦人科悪性腫瘍化学療法研究機構(JGOG)総会
  • Place of Presentation: 東京
  • Year and Date: 2012-11-30
• [Presentation] 子宮内膜癌におけるSteroid Sulfatase阻害剤の有用性に関する検討 (2012)
  • Author(s): 西本光男、宇都宮裕貴、志賀尚美、山下泰恒、辻圭太、海法道子、鈴木史彦、徳永英樹、伊藤潔、八重樫伸生
  • Organizer: 第25回日本内分泌学会東北地方会
  • Place of Presentation: 秋田
  • Year and Date: 2012-11-17
• [Presentation] Biological roles of estrogen and progesterone in endometrial carcinoma (2012)
  • Author(s): Ito. K
  • Organizer: 15th International Congress on Hormonal Steroids and Hormones & Cancer(ICHSHC)
  • Place of Presentation: Kanazawa, Japan
  • Year and Date: 2012-11-15
• [Presentation] 子宮体部漿液性腺癌においてmiR-34bはエピジェネティックに制御され、癌の浸潤・転移に関与する (2012)
  • Author(s): 鈴木史彦、永瀬智、赤平純一、廣木恵理、伊藤潔、宇都宮裕貴、笹野公伸、八重樫伸生
  • Organizer: 第71回日本癌学会
  • Place of Presentation: 札幌
  • Year and Date: 2012-09-21
• [Presentation] Identification of novel estrogen receptorαtarget gene and its function in endometrial cancer (2012)
  • Author(s): Shigeta S , Utsunomiya H, Ito K, Niikura H, Nagase S, Yoshinaga K, Sasano H, Yaegashi N
  • Organizer: 60th Annual Clinical Meeting of the American College of Obstetricians and Gynecologists
  • Place of Presentation: San Diego, USA
  • Year and Date: 2012-05-07
• [Presentation] 子宮体部漿液性腺癌においてmicoRNA-34bは浸潤性および足場非依存性増殖能を制御する (2012)
  • Author(s): 鈴木史彦、永瀬智、赤平純一、廣木恵理、伊藤潔、宇都宮祐貴、菅原準一、笹野公伸、八重樫伸生
  • Organizer: 第64回日本産科婦人科学会
  • Place of Presentation: 神戸
  • Year and Date: 2012-04-13
• [Presentation] 東日本大震災と産婦人科医療―当日、その後、そしてこれから―(特別講演) (2012)
  • Author(s): 伊藤潔
  • Organizer: 北海道産婦人科医会学術講演会
  • Place of Presentation: 札幌
  • Year and Date: 2012-03-04
• [Presentation] 東日本大震災と産婦人科医療―当日、その後、そしてこれから―（特別講演） (2012)
  • Author(s): 伊藤 潔
  • Organizer: 北海道産婦人科医会学術講演会(招待講演)
  • Place of Presentation: 札幌
• [Presentation] 子宮内膜ポリープの診断と取り扱い―産婦人科診療ガイドライン婦人科外来編2011―(ワークショップ) (2011)
  • Author(s): 伊藤潔
  • Organizer: 第59回北日本産科婦人科学会
  • Place of Presentation: 秋田
  • Year and Date: 2011-09-24
• [Presentation] 子宮内膜細胞診の結果と臨床対応の狭間のピットホール(ワークショップ) (2011)
  • Author(s): 伊藤潔、黒澤大樹、小澤信義、田勢亨、新倉仁、岡本聡、秀城浩司、渡辺康子、及川洋恵、笹野公伸、八重樫伸生
  • Organizer: 第52回日本臨床細胞学会春季大会
  • Place of Presentation: 福岡
  • Year and Date: 2011-05-21
• [Presentation] 子宮内膜細胞診の結果と臨床対応の狭間のピットホール（ワークショップ） (2011)
  • Author(s): 伊藤 潔、黒澤大樹 、小澤信義、田勢 亨、新倉 仁、岡本 聡、秀城浩司、渡辺康子 、及川洋恵、笹野公伸、八重樫伸生
  • Organizer: 第52回日本臨床細胞学会総会春期大会(招待講演)
  • Place of Presentation: 福岡
• [Presentation] 子宮内膜ポリープの診断と取り扱い―産婦人科診療ガイドライン 婦人科外来編2011―（ワークショップ） (2011)
  • Author(s): 伊藤 潔
  • Organizer: 第５９回北日本産科婦人科学会(招待講演)
  • Place of Presentation: 秋田
• [Presentation] ヒト子宮内膜癌におけるCRH発現と予後の関連
  • Author(s): 佐藤菜保子、高木清司、鈴木貴、三木康宏、割田仁、福土審、佐藤冨美子 八重樫伸生、伊藤潔
  • Organizer: 第51回日本癌治療学会
  • Place of Presentation: 京都
• [Presentation] 日本人女性における食物摂取と子宮体部類内膜腺癌発症リスクについての症例対照研究
  • Author(s): 重田昌吾、永瀬智、高山真、豊島将文、宇都宮裕貴、菅原準一、伊藤潔、八重樫伸生
  • Organizer: 第61回北日本産科婦人科学会学学術講演会
  • Place of Presentation: 旭川
• [Presentation] 子宮内膜癌におけるSteroid sulfatase 阻害剤の有効性に関する検討
  • Author(s): 西本光男、宇都宮裕貴、志賀尚美、海北道子、鈴木史彦、徳永英樹、伊藤潔、八重樫伸生
  • Organizer: 第61回北日本産科婦人科学会学学術講演会
  • Place of Presentation: 旭川
• [Presentation] 子宮内膜癌におけるSteroid sulfatase 阻害剤の有用性に関する検討
  • Author(s): 西本光男、宇都宮裕貴、志賀尚美、辻圭太、海法道子、鈴木史彦、徳永英樹、伊藤潔、八重樫伸生
  • Organizer: 日本産婦人科学会 第65回学術講演会
  • Place of Presentation: 札幌
• [Presentation] 子宮体部漿液性腺癌におけるmicroRNA-34bの癌抑制的な機能の検討
  • Author(s): 鈴木史彦、永瀬智、廣木恵理、宇都宮裕貴、伊藤潔、新倉仁、赤平純一、笹野公伸、八重樫伸生
  • Organizer: 日本産婦人科学会 第65回学術講演会
  • Place of Presentation: 札幌
• [Presentation] Biological roles of estrogen and progesterone in endometrial carcinoma
  • Author(s): Ito. K
  • Organizer: 15th International Congress on Hormonal Steroids and Hormones & Cancer(ICHSHC)
  • Place of Presentation: Kanazawa, JAPAN
  • Invited
• [Book] Gynecological malignancies and diet in menopause (2013)
  • Author(s): Ito K, Sasano H, Yaegashi N
  • Total Pages: 469
  • Publisher: Humana Press
• [Book] 不正性器出血、機能性子宮出血、子宮内膜ポリープ今日の治療指針-私はこう治療している (2013)
  • Author(s): 伊藤潔
  • Publisher: 医学書院
• [Book] Gynecological malignancies and diet in menopause (2013)
  • Author(s): Kiyoshi Ito, Hironobu Sasano, Nobuo Yaegashi
  • Publisher: Humana Press
• [Book] TODAY'S THERAPY 2013 (2013)
  • Author(s): 伊藤潔(分担執筆）
  • Publisher: 不正性器出血、機能性子宮出血、子宮内膜ポリープ 今日の治療指針 －私はこう治療しているー
• [Book] 卵巣癌.エビデンスに基づいたがん薬物療法エキスパートマニュアル (2012)
  • Author(s): 伊藤潔、八重樫伸生
  • Total Pages: 533
  • Publisher: 総合医学社
• [Book] 不正性器出血、機能性子宮出血、子宮内膜ポリープ： 今日の治療指針―私はこう治療している―ＴODAY’S THERAPY 2012 (分担執筆） (2012)
  • Author(s): 伊藤 潔
  • Publisher: 医学書院
• [Book] 今日の治療指針―私はこう治療している―ＴODAY’S THERAPY 2012 (2012)
  • Author(s): 伊藤 潔
  • Publisher: 医学書院
• [Book] 患者さんとご家族のための子宮頚がん・子宮体がん・卵巣がん治療ガイドラインの解説 (2011)
  • Author(s): 伊藤潔
  • Publisher: 金原出版
• [Book] 子宮体癌今日の治療指針-私はこう治療している (2011)
  • Author(s): 伊藤潔
  • Publisher: 医学書院
• [Book] 患者さんとご家族のための子宮頚がん・子宮体がん・卵巣がん治療ガイドラインの解説 (2011)
  • Author(s): 伊藤 潔
  • Publisher: 金原出版
• [Book] 今日の治療指針―私はこう治療している―ＴODAY’S THERAPY 2011 (2011)
  • Author(s): 伊藤 潔
  • Publisher: 医学書院
• [Book] 医療情報サービス Minds（マインズ） (2011)
  • Author(s): 伊藤 潔
  • Publisher: 日本医療機能評価機構
• [Remarks]
  • URL: http://irides.tohoku.ac.jp/organization/medicine/05.html