| Project/Area Number |
23592530
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kochi University |
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Principal Investigator |
HYODO Masamitsu 高知大学, 教育研究部医療学系, 教授 (00181123)
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| Co-Investigator(Kenkyū-buntansha) |
KOMORI Masahiro 高知大学, 教育研究部医療学系, 講師 (30565742)
NISHIKUBO Kaori 高知大学, 教育研究部医療学系, 助教 (60380242)
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| Project Period (FY) |
2011-04-28 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | 嚥下障害 / 嚥下内視鏡検査 / 嚥下造影検査 / 咽喉頭感覚刺激 / 薬物治療 / 外科的治療 / 嚥下訓練 / 病態評価 / カプサイシン / 嚥下機能の定量的評価 |
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| Research Abstract |
As an objective and quantitative evaluation of dysphagia, laryngeal elevation delay time (LEDT) and pharyngeal transit time (PTT) by videofluorography significantly extended and correlated with the severity of dysphagia. Scoring system of videoendoscopic examination for swallowing, which we proposed, was beneficial for assessing the features of dysphagia and oral alimentation advisability.
In the treatment, LEDT and PTT improved by capsaicin administration through a temperature sensory stimulation effect. In patients whose glottal closure reflex and swallowing reflex initiation remain disturbed profoundly against 3-4 months' intensive conservative treatments, surgical intervention should be considered.
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