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Risk factors for eye diseases in the Hisayama study

Research Project

Project/Area Number 23592575
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Ophthalmology
Research InstitutionKyushu University

Principal Investigator

YASUDA Miho  九州大学, 大学病院, 助教 (00336033)

Co-Investigator(Kenkyū-buntansha) ISHIBASHI Tatsuro  九州大学, 大学院医学研究院眼科学分野, 教授 (30150428)
KIYOHARA Yutaka  九州大学, 大学院医学研究院環境医学分野, 教授 (80161602)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords疫学研究 / 危険因子 / 予防因子 / 有病率 / 発症率 / 加齢黄斑変性 / 糖尿病網膜症 / 近視性網膜症 / 防御因子 / 久山町研究 / 近視性黄斑変性 / 網膜静脈閉塞症 / コホート研究 / 遺伝的因子
Research Abstract

Glaucoma, diabetic retinopathy, and age-related macular degeneration (AMD) are the leading causes of irreversible visual impairment and blindness in elderly populations in Japan. Despite the magnitude of this problem, the pathogenesis of these diseases remains poorly understood. It is thus very important to determine the precise epidemiology of these diseases and to identify their risk factors to develop preventive measures of the disease. The purpose of this study was to examine the incidence of eye diseases and their risk factors in a prospective study of a general Japanese population.
Our findings suggest that the 9-year incidences of late AMD are lower among the Japanese than among white people in Western countries, while it is higher than among black people. Smoking habits and higher circulating WBC count are significant risk factors for the development of late AMD in the Japanese.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (29 results)

All 2013 2012 2011 Other

All Journal Article (12 results) (of which Peer Reviewed: 3 results) Presentation (13 results) (of which Invited: 4 results) Book (4 results)

  • [Journal Article] 糖尿病網膜症の疫学2013

    • Author(s)
      安田 美穂
    • Journal Title

      OCULISTA

      Volume: 8 Pages: 1-5

    • Related Report
      2013 Annual Research Report
  • [Journal Article] 加齢黄斑変性の疫学2013

    • Author(s)
      安田 美穂
    • Journal Title

      Progress in medicine

      Volume: 10 Pages: 13-16

    • Related Report
      2013 Annual Research Report
  • [Journal Article] 近視の疫学2013

    • Author(s)
      安田 美穂
    • Journal Title

      日本の眼科

      Volume: 84 Pages: 865-869

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Prevalence and risk factors for myopic retinopathy in a Japanese population : the Hisayama Study2012

    • Author(s)
      Asakuma T, Yasuda M, Ninomiya T, Noda Y, Arakawa S, Hashimoto S, Ohno-Matsui K, Kiyohara Y, Ishibashi T
    • Journal Title

      Ophthalmology

      Volume: 119巻 Pages: 1760-176

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prevalence and risk factors for myopic retinopathy in a Japanese population: the Hisayama Study.2012

    • Author(s)
      Asakuma T, Yasuda M, Ninomiya T, Noda Y, Arakawa S, Hashimoto S, Ohno-Matsui K, Kiyohara Y, Ishibashi T.
    • Journal Title

      Ophthalmology

      Volume: 119 Pages: 1760-1765

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] High serum bilirubin levels and diabetic retinopathy: The Hisayama Study.2011

    • Author(s)
      Yasuda M, Kiyohara Y, Hata Y, Arakawa S, Yonemoto K, Doi Y, Iida M, Ishibash T.
    • Journal Title

      Ophthalmology

      Volume: 118 Pages: 1423-1428

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 網膜硝子体疾患の疫学2011

    • Author(s)
      安田美穂
    • Journal Title

      臨床眼科

      Volume: 65 Pages: 324-325

    • Related Report
      2011 Research-status Report
  • [Journal Article] 糖尿病網膜症の疫学2011

    • Author(s)
      安田美穂
    • Journal Title

      Diabetes Frontier

      Volume: 22 Pages: 358-361

    • Related Report
      2011 Research-status Report
  • [Journal Article] 糖尿病網膜症とは?2011

    • Author(s)
      安田美穂
    • Journal Title

      眼科ケア

      Volume: 13 Pages: 24-27

    • Related Report
      2011 Research-status Report
  • [Journal Article] 加齢黄斑変性(AMD)の疫学2011

    • Author(s)
      安田美穂
    • Journal Title

      Geriat. Med (老年医学)

      Volume: 49 Pages: 385-387

    • Related Report
      2011 Research-status Report
  • [Journal Article] わが国の成人の失明原因となる疾患2011

    • Author(s)
      安田美穂
    • Journal Title

      日本医事新報

      Volume: 4574 Pages: 55-56

    • Related Report
      2011 Research-status Report
  • [Journal Article] 加齢黄斑変性2011

    • Author(s)
      安田美穂
    • Journal Title

      日本医事新報

      Volume: 4532 Pages: 78-84

    • Related Report
      2011 Research-status Report
  • [Presentation] Trends in prevalence of AMD in a defined Japanese population: Hisayama Study.2013

    • Author(s)
      Yasuda M, Hashimoto S, Arakawa S, Kiyohara Y, Ishibashi T.
    • Organizer
      The 8th APVRS Congress & The 52nd Annual meeting of Japanese Retina and Vitreous Society
    • Place of Presentation
      Nagoya, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] 加齢黄斑変性の有病率の変化2013

    • Author(s)
      安田美穂 橋本左和子 田原朋子 荒川聡 清原裕 石橋達朗
    • Organizer
      第67回日本臨床眼科学会
    • Place of Presentation
      横浜市
    • Related Report
      2013 Annual Research Report
  • [Presentation] 糖尿病網膜症の14年発症率と危険因子の検討:久山町研究2013

    • Author(s)
      安田美穂 橋本左和子 田原朋子 荒川聡 清原裕 石橋達朗
    • Organizer
      第19回日本糖尿病眼科学会
    • Place of Presentation
      神戸市
    • Related Report
      2013 Annual Research Report
  • [Presentation] PCVの疫学2012

    • Author(s)
      安田美穂
    • Organizer
      第29回眼循環学会
    • Place of Presentation
      秋田市
    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Invited
  • [Presentation] AMDの疫学2012

    • Author(s)
      安田美穂
    • Organizer
      東京黄斑疾患研究会
    • Place of Presentation
      東京都
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] Prevalence and systemic relevant factors for polypoidal choroidal vasculopathy in a general Japanese population: the Hisayama Study.2011

    • Author(s)
      Yasuda M, Oshima Y, T, Hashimoto S, Arakawa S, Kiyohara Y, Ishibashi T.
    • Organizer
      Association for Research in Vision and Ophthalmology
    • Place of Presentation
      Fort Lauderdale, USA
    • Related Report
      2011 Research-status Report
  • [Presentation] 糖尿病網膜症発症予防と住民健診:久山町研究の成果2011

    • Author(s)
      安田美穂
    • Organizer
      第17回日本糖尿病眼学会総会 シンポジウム(招待講演)
    • Place of Presentation
      東京都
    • Related Report
      2011 Research-status Report
  • [Presentation] 食事やサプリメントがAMDを予防する?2011

    • Author(s)
      安田美穂
    • Organizer
      第65回日本臨床眼科学会(招待講演)
    • Place of Presentation
      東京都
    • Related Report
      2011 Research-status Report
  • [Presentation] 加齢黄斑変性の疫学2011

    • Author(s)
      安田美穂
    • Organizer
      第11回日本抗加齢医学学会総会(招待講演)
    • Place of Presentation
      京都市
    • Related Report
      2011 Research-status Report
  • [Presentation] 近視の疫学2011

    • Author(s)
      安田美穂
    • Organizer
      眼光学学会、シンポジウム(招待講演)
    • Place of Presentation
      東京都
    • Related Report
      2011 Research-status Report
  • [Presentation] 糖尿病網膜症の疫学

    • Author(s)
      安田美穂
    • Organizer
      Diabetes Science & Retinal Vascular Function
    • Place of Presentation
      東京都
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 糖尿病網膜症の疫学

    • Author(s)
      安田美穂
    • Organizer
      Hisayama Study Conference 2012
    • Place of Presentation
      福岡市
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Prevalence, incidence and its associations of AMD and PCV in the Hisayama Study.

    • Author(s)
      Yasuda Miho
    • Organizer
      The forth joint meeting of Korea-China-Japan Ophthalmologists
    • Place of Presentation
      福岡市
    • Related Report
      2012 Research-status Report
    • Invited
  • [Book] あたらしい眼科2013

    • Author(s)
      安田美穂
    • Publisher
      メディカル葵出版
    • Related Report
      2012 Research-status Report
  • [Book] あたらしい眼科2012

    • Author(s)
      安田美穂
    • Publisher
      メディカル葵出版
    • Related Report
      2012 Research-status Report
  • [Book] RETINA  Medicine2012

    • Author(s)
      安田美穂
    • Publisher
      先端医学社
    • Related Report
      2012 Research-status Report
  • [Book] 糖尿病網膜症のすべて2012

    • Author(s)
      安田美穂
    • Publisher
      中山書店
    • Related Report
      2012 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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