research on retinal degeneration
| Project/Area Number |
23592578
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Ophthalmology
|
|---|
| Research Institution | University of Miyazaki |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
CHUMAN Hideki 宮崎大学, 医学部, 准教授 (20244204)
KOZAWA Maki 宮崎大学, 医学部, 助教 (00433061)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
|
|---|
| Keywords | 眼 / 網膜 / 網膜変性 / 循環障害 / 視神経 / 電気生理 / 未熟児網膜症 / 虚血性視神経症 / 抗VEGF抗体 / ステロイド / クリスタリン網膜症 / 色素変性 |
|---|
| Research Abstract |
We analysed causative genes of retinal degenertions. We have found several mutations in peripherin-RDSgene or CYP4 V2 gene of Bietti crystalline retinopathy. In x-linked retinitis pigmentosa gene patients, we analysed ORF15 region of RPGR gene and RP2 gene. In congenital retinoschisis patients with RS-1 gene mutation, we performed vitreous surgeries and reported the results.
We also established experimental model of ischemic optic neuropathy and successfully recorded STR. Recording of STR revealed innner retinal function.
|
Report
(4 results)
Research Products
(124 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 非動脈炎性虚血性視神経症ラットモデルに対するOCTを用いたステロイド治療の効果検討2012
Author(s)
前久保知行,中馬秀樹,河野尚子,杉本貴子,小澤摩記,川原亮輝,児玉悠,大迫貴子,石合理崇,小溝崇史,森真喜子,中山恵介,直井信久
Organizer
第116回日本眼科学会総会
Place of Presentation
東京
Year and Date
2012-04-05
Related Report
-
-
-
-
[Presentation] 遺伝子治療2011
Author(s)
直井信久
Organizer
第7回JRPS網脈絡膜変性フォーラム
Place of Presentation
東京
Year and Date
2011-12-04
Related Report
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 網膜電図と視覚誘発電位による非動脈炎性虚血性視神経症ラットモデルの視機能評価2011
Author(s)
大迫貴子,中馬秀樹,河野尚子,杉本貴子,小澤摩記,川原亮輝,前久保知行、持原健勝,石合理崇,児玉悠,髙田真知,直井信久
Organizer
第115回日本眼科学会総会
Place of Presentation
東京
Year and Date
2011-05-12
Related Report
-
-
-
-
-
-
-
-
[Presentation] Refractive outcome of bevacizumab treatment of retinopathy of prematurity2011
Author(s)
T.Maekubo,H.Chuman,T.Oosako,M.Ishiai,Y.Kodama,A.Kawahara,T.Sugimoto,M.Kozawa,N.Nao-i,Y.Fukushima,M.Takata,A.Kawahara
Organizer
XXIX Congress of the ESCRS
Place of Presentation
Vienna Austria
Related Report
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
