Influence of high fat diet in the retina
Project/Area Number |
23592588
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Ophthalmology
|
Research Institution | Keio University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
OZAWA Yoko 慶應義塾大学, 医学部, 講師 (90265885)
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | 網膜 / 生活習慣病 / 肥満 / 糖尿病 |
Research Abstract |
Recent increase in the prevalence of metabolic syndrome, which includes vision threatening diseases such as diabetic retinopathy and age-related macular degeneration, is a social issue. Metabolic syndrome includes obesity and high fat diet, which are also known risk factors of diabetic retinopathy and age-related macular degeneration. However, the underlying mechanisms of the relationship between obesity and high fat diet, and retinal diseases were still obscure. In this study, we analyzed the influence of high fat diet in the retina of mice; we evaluated systemic and retinal inflammatory cytokines.
|
Report
(4 results)
Research Products
(43 results)
-
-
-
-
-
-
-
-
[Journal Article] Presence and physiological function of Renin-Angiotensin System in mouse lacrimal gland.2012
Author(s)
Yaguchi S, Ogawa Y, Shimmura S, Hatou S, Nakamura S, Inaba T, Imada T, Ozawa Y, Kawakami Y, Ishida S, Tsubota K.
-
Journal Title
Invest Ophthalmol Vis Sci.
Volume: 53
Issue: 9
Pages: 5416-25
DOI
Related Report
Peer Reviewed
-
-
[Journal Article] Soluble Vascular Adhesion Protein-1 Accumulates in Proliferative Diabetic Retinopathy.2012
Author(s)
Murata M, Noda K, Fukuhara J, Kanda A, Kase S, Saito W, Ozawa Y, Mochizuki S, Kimura S, Mashima Y, Okada Y, Ishida S.
-
Journal Title
Invest Ophthalmol Vis Sci.
Volume: 53
Issue: 7
Pages: 4055-62
DOI
Related Report
Peer Reviewed
-
-
-
-
[Journal Article] Acute visual field defect following vitrectomy determined to originate from optic nerve by electrophysiological tests.2012
Author(s)
Uchida A, Shinoda K, Matsumoto C.S, Kawai M, Kawai S, Ohde H, Ozawa Y, Ishida S, Inoue M, Mizota A, Tsubota K.
-
Journal Title
Case Rep Ophthalmol.
Volume: 3
Issue: 3
Pages: 396-405
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
[Presentation] 狭義加齢黄斑変性に対するpro re nateによるラニビズマブ硝子体注射2013
Author(s)
鈴木美砂, 永井紀博, 永井香奈子, 篠田肇, 内田敦郎, 厚東隆志, 持丸博史, 富田洋平, 佐々木真理子, 坪田一男, 小沢洋子
Organizer
第67回日本臨床眼科学会
Place of Presentation
神奈川 横浜
Related Report
-
-
[Presentation] Associations of Serum Lipids with Macular Morphology in Patients without Diabetic Macular Edema2013
Author(s)
Sasaki M, Kawashima M, Kawasaki R, Kawai M, Uchida A, Koto T, Mochimaru H, Shinoda H, Jie Jin Wang, Tsubota K, Ozawa Y
Organizer
Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting
Place of Presentation
Washington State Convention & Trade Center Seattle, USA
Related Report
-
[Presentation] Baseline characteristics and response to intravitreal ranibizumab therapy for age-related macular degeneration2013
Author(s)
Suzuki M, Nagai N, Izumi-Nagai K, Shinoda H, Koto T, Uchida A, Mochimaru H, Yuki K, Tsubota K, Ozawa Y
Organizer
Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting
Place of Presentation
Washington State Convention & Trade Center Seattle, USA
Related Report
-
[Presentation] 狭義加齢黄斑変性に対するpro re nateによるラニビズマブ硝子体注射.2013
Author(s)
3. 鈴木美砂, 永井紀博, 永井香奈子, 篠田肇, 内田敦郎, 厚東隆志, 持丸博史, 富田洋平, 佐々木真理子, 坪田一男, 小沢洋子.
Organizer
第67回日本臨床眼科学会
Place of Presentation
パシフィコ横浜 神奈川県 横浜市
Related Report
-
-
[Presentation] 健常者における黄斑色素密度と血清カロテノイド濃度の相関2012
Author(s)
永井紀博, 小林文貴, 永井香奈子, 鈴木美砂, 持丸博史, 内田敦郎, 厚東隆志, 篠田肇, 三宅誠司, 小林沙織, 坪田一男, 小沢洋子
Organizer
第66回日本臨床眼科学会
Place of Presentation
京都
Related Report
-
-
-
-
[Presentation] 片眼加齢黄斑変性患者における前駆病変と僚眼発症の関連2012
Author(s)
佐々木真理子, 川崎良, 内田敦郎, 厚東隆志, 持丸博史, 篠田肇, 鈴木美砂, 永井香奈子, 永井紀博, 坪田一男, 小沢洋子
Organizer
第116回日本眼科学会
Place of Presentation
東京
Related Report
-
-
-
-
-
-
-
[Presentation] Associations of Serum Lipids with Macular Morphology in Patients without Diabetic Macular Edema.
Author(s)
Sasaki M, Kawashima M, Kawasaki R, Kawai M, Uchida A, Koto T, Mochimaru H, Shinoda H, Jie Jin Wang, Tsubota K, Ozawa Y.
Organizer
Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting:
Place of Presentation
Washington State Convention & Trade Center Seattle, USA
Related Report
-
[Presentation] Baseline characteristics and response to intravitreal ranibizumab therapy for age-related macular degeneration.
Author(s)
Suzuki M, Nagai N, Izumi-Nagai K, Shinoda H, Koto T, Uchida A, Mochimaru H, Yuki K, Tsubota K, Ozawa Y.
Organizer
Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting
Place of Presentation
Washington State Convention & Trade Center Seattle, USA
Related Report
-
-