| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Research Abstract |
The OCT could demonstrate characterisitic photoreceptor abnormalities in patients with the Occult macular dystrophy (OMD) with RP1L1 mutation; disappearance of cone outer segment tip (COST) line, and blurring or disruption of photoreceptor inner segment ellipsoid (ISe). These finding could be also observed in patients without subjective visual disturbance.
In most of the patients without the RP1L1 mutation, the OCT features were different from the above findings. Patients with OMD, who were electrophysiologically diagnosed, may harbor various etiologies other than the RP1L1 gene mutation and new diagnostic criteria should be established.
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