| Project/Area Number |
23592644
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Shinshu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YUZURIHA Shunsuke 信州大学, 医学部, 准教授 (10270969)
MISHIMA Yoshito 信州大学, 医学部附属病院, 助教(診療) (80464098)
FUJITA Kennya 信州大学, 医学部附属病院, 講師 (00447781)
BAN Ryokuya 信州大学, 医学部附属病院, 講師 (30447784)
YANO Shiharu 信州大学, 医学部, 助教 (10531907)
YASUNAGA Yoshichika 信州大学, 医学部, 助教 (40596946)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2012: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2011: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
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| Keywords | 顔面表情筋 / 遅筋線維 / 発熱 / サーモグラフィ / ミュラー筋機械受容器 / 固有感覚 / 三叉神経中脳路核 / 青斑核 / 速筋線維 / 遅筋収縮 / 温度上場 / サーモグラフィー / 不随意的収縮 / 遅筋 |
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| Research Abstract |
Facial mimic muscles are contracted voluntarily or reflexively. Although these muscle consist of fast- and slow-twitch fibers, they lack intrinsic muscle spindles normally required to induce reflex contraction of slow-twitch fibers. We found that the mechanoreceptors in Mueller's muscle, which locates between the levator muscle and the tarsus, function as extrinsic mechanoreceptors to induce reflex contraction of the facial slow-twitch fibers. To strongly retract the upper eyelid, increased voluntary contraction of the levator non-skeletal fast-twitch fibers stretches the mechanoreceptors in Mueller's muscle to strongly evoke trigeminal proprioception. This proprioception stimulates the facial motor neurons to induce reflex contraction of the facial slow-twitch fibers via the mesencephalic trigeminal neurons and the locus ceruleus, both of which are connected with gap junctions. This reflex contraction of the facial slow-twitch fibers thermographically produces heat.
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