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Development of the device for healing ability of diabetic and ischemic ulcers

Research Project

Project/Area Number 23592652
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Plastic surgery
Research InstitutionSaitama Medical University

Principal Investigator

ICHIOKA Shigeru  埼玉医科大学, 医学部, 教授 (60306272)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords創傷治癒
Research Abstract

Chronic wounds due to diabetes mellitus (DM) and/or peripheral arterial disease (PAD) often occur in the pedal region peripheral to the ankle. To predict wound healing potential of the limb ulcers, skin perfusion pressure (SPP) and transcutaneous oxygen tension (TcPO2) have recently become popular as the parameters that reflect skin microcirculation. On the other hand, ultrasonography for the macrocirculatory vessels has already prevailed widely as the standard vascular investigation. The skin microcirculation peripheral to the ankle probably depends on the macrocirculatory blood flow at the ankle level. Thus, this study aims to estimate weather the blood flow of the anterior tibial artery (ATA) and the posterior tibial artery at the ankle level reflect the values of SPP and TcPO2 on the foot. .

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (33 results)

All 2014 2013 2012

All Journal Article (18 results) (of which Peer Reviewed: 14 results) Presentation (14 results) Book (1 results)

  • [Journal Article] 下肢潰瘍に対する足関節レベルの血管超音波検査の有用性2014

    • Author(s)
      関谷直美、市岡滋
    • Journal Title

      皮膚微小循環血流との比較脈管学

      Volume: 54 Pages: 45-50

    • Related Report
      2013 Final Research Report
  • [Journal Article] Comparison of collagen matrix treatment impregnated with platelet rich plasma vs bone marrow.2014

    • Author(s)
      Minamimura A, Ichioka S, Sano H, Sekiya N.
    • Journal Title

      J Plast Surg Hand Surg.

      Volume: Feb;48(1) Issue: 1 Pages: 15-20

    • DOI

      10.3109/2000656x.2013.793193

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Which cleansing care is better, foot bath or shower? Analysis of 236 limb ulcers.2013

    • Author(s)
      Sano H, Ichioka S.
    • Journal Title

      Int Wound J

      Volume: Nov 20 Issue: 5 Pages: 577-580

    • DOI

      10.1111/iwj.12167

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preservation of the properties of elastic plasma protein plus platelet film for wound dressing.2013

    • Author(s)
      Sano H, Ichioka S, Minamimura A, Tanaka R, Ikebuchi K, Suzuki M.
    • Journal Title

      J Plast Surg Hand Surg.

      Volume: Dec;47(6): Pages: 458-61

    • DOI

      10.3109/2000656x.2013.779582

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Treatment of chronic ulcer with elastic plasma protein and platelet film for wound dressing.2013

    • Author(s)
      Sano H, Ichioka S, Minamimura A, Tanaka R, Ikebuchi K, Suzuki M.
    • Journal Title

      J Plast Surg Hand Surg.

      Volume: Dec;47(6) Pages: 462-6

    • DOI

      10.3109/2000656x.2013.783485

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of a poly glycolic acid (PGA)/collagen composite nanofibre scaffold on cell migration and neovascularisation in vivo skin defect model.2013

    • Author(s)
      Sekiya N, Ichioka S, Terada D, Tsuchiya S, Kobayashi H.
    • Journal Title

      J Plast Surg Hand Surg.

      Volume: Dec;47(6) Pages: 498-502

    • DOI

      10.3109/2000656x.2013.788507

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of nitric oxide in the wound bed microcirculatory change during negative pressure wound therapy.2013

    • Author(s)
      Sano H, Ichioka S.
    • Journal Title

      Int Wound J.

      Volume: Jul 9. Issue: 4 Pages: 397-401

    • DOI

      10.1111/iwj.12121

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effect of a hydrocolloid dressing containing ceramide-2 on split-thickness wounds in a laser-induced erosion model2013

    • Author(s)
      Tsuchiya S, Ichioka S, Sekiya N, Tajima S, Iwasaki T, Numata S
    • Journal Title

      Adv Skin Wound Care

      Volume: 26(5) Issue: 5 Pages: 224-9

    • DOI

      10.1097/01

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effect of a hydrocolloid dressing containing ceramide-2 on split-thickness wounds in a laser-induced erosion model.2013

    • Author(s)
      Tsuchiya S, Ichioka S, Sekiya N, Tajima S, Iwasaki T, Numata S.
    • Journal Title

      Adv Skin Wound Care.

      Volume: May;26(5) Issue: 5 Pages: 224-9

    • DOI

      10.1097/01.asw.0000428952.00149.77

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] How should we manage multiple skin ulcers associated with calciphylaxis?2012

    • Author(s)
      Sato T, Ichioka S
    • Journal Title

      J Dermatol

      Volume: (In press) Issue: 11 Pages: 966-968

    • DOI

      10.1111/j.1346-8138.2012.01510.x

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Treatment of venous ulcers with bone marrow-impregnated collagen matrix.2012

    • Author(s)
      Sano H, Ichioka S, Kouraba S, Minamimura A, Sato T, Sekiya N, Yasuta M.
    • Journal Title

      J Plast Surg Hand Surg.

      Volume: 46 Issue: 1 Pages: 37-44

    • DOI

      10.3109/2000656x.2011.633392

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Optimal use of negative pressure wound therapy in treating2012

    • Author(s)
      Gupta S, Ichioka S.
    • Journal Title

      Int Wound J.

      Volume: 9 Issue: s1 Pages: 8-16

    • DOI

      10.1111/j.1742-481x.2012.01012.x

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] The estimation of tissue loss during tangential hydrosurgical debridement2012

    • Author(s)
      Matsumura H, Nozaki M, Watanabe K, Sakurai H, Kawakami S, Nakazawa H, Matsumura I, Katahira J, Inokuchi S, Ichioka S, Ikeda H, Mole T, Smith J, Martin R, Aikawa N
    • Journal Title

      Ann Plast Surg

      Volume: 69(5) Issue: 5 Pages: 521-5

    • DOI

      10.1097/sap.0b013e31826d2961

    • Related Report
      2013 Final Research Report
  • [Journal Article] Influence of mechanical forces as a part of nail configuration2012

    • Author(s)
      Sano H, Ichioka S
    • Journal Title

      Dermatology

      Volume: 225(3) (Epub 2012 Nov 6) Issue: 3 Pages: 210-4

    • DOI

      10.1159/000343470

    • Related Report
      2013 Final Research Report
  • [Journal Article] Influence of oxygen on wound healing dynamics : assessment in a novel wound mouse model under a variable oxygen environment2012

    • Author(s)
      Sano H, Ichioka S, Sekiya N
    • Journal Title

      PLoS One

      Volume: 7(11) (Epub 2012 Nov 28) Issue: 11 Pages: e50212-e50212

    • DOI

      10.1371/journal.pone.0050212

    • Related Report
      2013 Final Research Report
  • [Journal Article] Treatment of venous ulcers with bone marrow-impregnated collagen matrix.2012

    • Author(s)
      Sano H, Ichioka S, Kouraba S, Minamimura A, Sato T, Sekiya N, Yasuta M.
    • Journal Title

      J Plast Surg Hand Surg.

      Volume: 46 Pages: 37-44

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pressure ulcer occurrence following the great East Japan earthquake: observations from a disaster medical assistance team .2012

    • Author(s)
      Sato T, Ichioka S.
    • Journal Title

      Ostomy Wound Manage.

      Volume: 58 Pages: 70-75

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] In vivo analysis of skin microcirculation and the role of nitric oxide during vibration.2012

    • Author(s)
      Ichioka S, Yokogawa H, Nakagami G, Sekiya N, Sanada H.
    • Journal Title

      Ostomy Wound Manage.

      Volume: 57 Pages: 40-47

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Diversity in Surgical Wound Management2014

    • Author(s)
      市岡滋
    • Organizer
      第57回日本形成外科学会学術集会
    • Place of Presentation
      長崎ブリックホール
    • Year and Date
      2014-04-10
    • Related Report
      2013 Final Research Report
  • [Presentation] 創傷をgateとしたチーム医療の作り方2014

    • Author(s)
      市岡滋
    • Organizer
      第12回日本フットケア学会年次学術集会
    • Place of Presentation
      なら100年記念館
    • Year and Date
      2014-03-07
    • Related Report
      2013 Final Research Report
  • [Presentation] 褥瘡・難治性創傷の最新治療2014

    • Author(s)
      市岡滋
    • Organizer
      第10回日本褥瘡学会中部地方会学術集会
    • Place of Presentation
      アクトシティー浜松
    • Year and Date
      2014-03-02
    • Related Report
      2013 Final Research Report
  • [Presentation] 下肢創傷管理技術の最先端2014

    • Author(s)
      市岡滋
    • Organizer
      第4回大阪循環器病懇話会
    • Place of Presentation
      ヒルトンホテル大阪
    • Year and Date
      2014-02-23
    • Related Report
      2013 Final Research Report
  • [Presentation] 創傷治療のup to date2013

    • Author(s)
      市岡滋
    • Organizer
      第105回関西形成外科学会学術集会
    • Place of Presentation
      大阪市立大学
    • Year and Date
      2013-12-07
    • Related Report
      2013 Final Research Report
  • [Presentation] Diabetic Footにおける創傷管理のupdate2013

    • Author(s)
      市岡滋
    • Organizer
      第28回日本糖尿病合併症学会
    • Place of Presentation
      旭川グランドホテル
    • Year and Date
      2013-09-13
    • Related Report
      2013 Final Research Report
  • [Presentation] 医師と看護師が伝授する創傷マネージメントのup to date2013

    • Author(s)
      市岡滋
    • Organizer
      第15回日本褥瘡学会学術集会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2013-07-20
    • Related Report
      2013 Final Research Report
  • [Presentation] VAC ATS治療システムUpdate2013

    • Author(s)
      市岡滋
    • Organizer
      第56回日本形成外科学会総会・学術集会
    • Place of Presentation
      京王プラザ
    • Year and Date
      2013-04-04
    • Related Report
      2013 Final Research Report
  • [Presentation] 褥瘡・難治性創傷の最新治療2012

    • Author(s)
      市岡滋
    • Organizer
      第27回日本静脈経腸栄養学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2012-02-24
    • Related Report
      2013 Final Research Report
  • [Presentation] Japanese Experience in VAC Optimal Use of NPWT in treating Pressure Ulcers2012

    • Author(s)
      Ichioka S
    • Organizer
      The 4^<th> Congress of World Union of Wound Healing Society
    • Place of Presentation
      Pacifico Yokohama
    • Related Report
      2013 Final Research Report
  • [Presentation] The Implications for Innovation in NPWT2012

    • Author(s)
      Ichioka S
    • Organizer
      The 4^<th> Congress of World Union of Wound Healing Society
    • Place of Presentation
      Pacifico Yokohama
    • Related Report
      2013 Final Research Report
  • [Presentation] HISTORY AND PRESENT STATUS OF NPWT IN JAPAN2012

    • Author(s)
      Ichioka S
    • Organizer
      The 4^<th> Congress of World Union of Wound Healing Society
    • Place of Presentation
      Pacifico Yokohama
    • Related Report
      2013 Final Research Report
  • [Presentation] The Brief History of Negative Pressure Wound Therapy2012

    • Author(s)
      Ichioka S
    • Organizer
      The 4^<th> Congress of World Union of Wound Healing Society
    • Place of Presentation
      Pacifico Yokohama
    • Related Report
      2013 Final Research Report
  • [Presentation] Clinical Evidence with Silver Dressing Technology2012

    • Author(s)
      Ichioka S
    • Organizer
      The 4^<th> Congress of World Union of Wound Healing Society
    • Place of Presentation
      Pacifico Yokohama
    • Related Report
      2013 Final Research Report
  • [Book] 創傷のすべて (市岡滋監修、安部正敏、寺師浩人、溝上祐子編集)2012

    • Publisher
      克誠堂
    • Related Report
      2013 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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