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Immunology and regenerative medicine-based approach to acute lung injury

Research Project

Project/Area Number 23592681
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Emergency medicine
Research InstitutionKeio University

Principal Investigator

FUJISHIMA Seitaro  慶應義塾大学, 医学部, 准教授 (00173419)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords炎症性肺疾患 / 急性呼吸促迫症候群 / ARDS
Research Abstract

1) We examined the mechanisms of exaggerated bleomycin-induced acute lung injury in IL-17-deficient mice, and found that IL-12-expressing dendritic cells were increased in the knockout mice. 2) In human endothelial cells, in association with the accelerated response, gene expression of TLR and NOD families were significantly affected under hyperoxia. 3) We examined the differentiation of human embryonic stem cells to alveolar epithelial cells under air-liquid interface, using SPC and AP5 as markers. The expression of SPC was increased at 20 days, but was decreased at 40 days, whereas that of AP5 was increased with time. 4) We examined lung stem cells and progenitor cells in autopsied lungs from patients with ARDS and IPF. In ARDS, accumulation of inflammatory cells in the early phase and metaplastic epithelial cells in the late phase were observed, but Musashi-1 and SPC double positive cells were not observed. In IPF, Musashi-1 and CCSP double positive cells were also not observed.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (77 results)

All 2014 2013 2012 2011 Other

All Journal Article (32 results) (of which Peer Reviewed: 20 results,  Open Access: 4 results) Presentation (34 results) (of which Invited: 8 results) Book (11 results)

  • [Journal Article] ALI/ARDSの診断と治療:バイオマーカー2014

    • Author(s)
      藤島清太郎
    • Journal Title

      呼吸器内科

      Volume: 25(3) Pages: 204-11

    • Related Report
      2013 Final Research Report
  • [Journal Article] A multicenter, prospective evaluation of quality of care and mortality in Japan based on the Surviving Sepsis Campaign guidelines2014

    • Author(s)
      Fujishima S, Gando S, et al
    • Journal Title

      J Infect Chemother

      Volume: 20(2) Issue: 2 Pages: 115-120

    • DOI

      10.1016/j.jiac.2013.09.003

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Epidemiology of severe sepsis in Japanese intensive care units: a prospective multicenter study2014

    • Author(s)
      Ogura H, Gando S, Saitoh D, Takeyama N, Kushimoto S, Fujishima S, Mayumi T, Araki T, Ikeda H, Kotani J, Miki Y, Shiraishi S, Suzuki K, Suzuki Y, Takuma K, Tsuruta R, Yamaguchi Y, Yamashita N, Aikawa N.
    • Journal Title

      J Infect Chemother

      Volume: 20 Issue: 3 Pages: 157-62

    • DOI

      10.1016/j.jiac.2013.07.006

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pharmacokinetics of a polyene antifungal agent, liposomal amphotericin B (L-AMB), in a severely burned patient.2014

    • Author(s)
      Sasaki J, Matsumoto K, Fujishima S, Morita K, Hori S.
    • Journal Title

      J Chemother

      Volume: 印刷中 Issue: 5 Pages: 312-314

    • DOI

      10.1179/1973947813y.0000000141

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] ALI/ARDSの診断と治療:バイオマーカー2014

    • Author(s)
      藤島清太郎
    • Journal Title

      呼吸器内科

      Volume: 25 Pages: 33-38

    • Related Report
      2013 Annual Research Report
  • [Journal Article] A multicenter, prospective validation study of the Japanese Association for Acute Medicine disseminated intravascular coagulation scoring system in patients with severe sepsis2013

    • Author(s)
      Gando S, Fujishima S, et al
    • Journal Title

      Crit Care

      Volume: 17 Issue: 3

    • DOI

      10.1186/cc12783

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Skew of plasma low- and high-density lipoprotein distributions to less dense subfractions in normotriglyceridemic chronic kidney disease patients on maintenance hemodialysis treatment2013

    • Author(s)
      Homma K, Fujishima S, et al
    • Journal Title

      Nephron Clin Pract

      Volume: 123 Issue: 1-2 Pages: 41-5

    • DOI

      10.1159/000351506

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The impact of body temperature abnormalities on the disease severity and outcome in patients with severe sepsis: an analysis from a multicenter, prospective survey of severe sepsis2013

    • Author(s)
      Kushimoto S, Gando S, Saitoh D, Mayumi T, Ogura H, Fujishima S, Araki T, Ikeda H, Kotani J, Miki Y, Shiraishi SI, Suzuki K, Suzuki Y, Takeyama N, Takuma K, Tsuruta R, Yamaguchi Y, Yamashita N, Aikawa N.
    • Journal Title

      Crit Care

      Volume: 17 Issue: 6

    • DOI

      10.1186/cc13106

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neuroleptic malignant syndrome-induced massive coagulopathy successfully treated by combination therapy of recombinant soluble thrombomodulin and antithrombin III2013

    • Author(s)
      Hayashida K, Fujishima S, Abe S, Shiroshita A, Hori S.
    • Journal Title

      Am J Emerg Med

      Volume: 31 Issue: 3 Pages: 636.e1-636.e3

    • DOI

      10.1016/j.ajem.2012.10.025

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Fatal overwhelming postsplenectomy infection caused by Streptococcus pneumoniae in mothers within 1 year after delivery: case report2013

    • Author(s)
      Hifumi T, Fujishima S, Chang B, Sasaki J, Kiriu N, Kato H, Inoue J, Koido Y
    • Journal Title

      J Infect Chemother

      Volume: 19 Issue: 6 Pages: 1202-5

    • DOI

      10.1007/s10156-013-0613-x

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 日本救急医学会Sepsis Registry特別委員会報告:Severe sepsisの早期予後予測指標の検討:septic shockと比較して2013

    • Author(s)
      樽井武彦,藤島清太郎,他
    • Journal Title

      日救急医会誌

      Volume: 24(5) Pages: 310-314

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 日本救急医学会Sepsis Registry特別委員会報告:肺炎・膿胸によるsevere sepsisの血液・巣培養結果と重症度の関係についての検討2013

    • Author(s)
      白石振一郎,藤島清太郎,他
    • Journal Title

      日救急医会誌

      Volume: 24(5) Pages: 310-314

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 日本救急医学会Sepsis Registry特別委員会報告:Severe sepsis患者におけるBody Mass Index(BMI)の影響日本救急医学会Sepsis Registry 535例の解析2013

    • Author(s)
      山下典雄,藤島清太郎,他
    • Journal Title

      日救急医会誌

      Volume: 24(5) Pages: 305-309

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 日本救急医学会Sepsis Registry特別委員会報告:Severe sepsisにおける体温は重症度と転帰に関連する2013

    • Author(s)
      久志本成樹,藤島清太郎,他
    • Journal Title

      日救急医会誌

      Volume: 24(5) Pages: 297-304

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 呼吸既感染症におけるプロカルシトニンのバイオマーカーとしての意義2013

    • Author(s)
      藤島清太郎
    • Journal Title

      分子呼吸器病

      Volume: 17(1) Pages: 48-53

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 急性呼吸促迫症候群(ARDS)の新定義と個別化治療戦略2013

    • Author(s)
      藤島清太郎
    • Journal Title

      呼吸器内科

      Volume: 23(4) Pages: 379-389

    • Related Report
      2013 Final Research Report
  • [Journal Article] 日本版敗血症診療ガイドライン2013

    • Author(s)
      織田成人、藤島清太郎、他
    • Journal Title

      日本集中治療医学会雑誌

      Volume: 20(1) Pages: 124-173

    • URL

      https://www.jstage.jst.go.jp/article/jsicm/20/1/20_124/_article/-char/ja/

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] ショック、敗血症、臓器障害における最新治療:急性呼吸促迫症候群(ARDS)エビデンスに基づく治療の個別化の試み2013

    • Author(s)
      藤島清太郎
    • Journal Title

      Shock (日本Shock学会雑誌)

      Volume: 27(2) Pages: 31-35

    • URL

      http://mol.medicalonline.jp/library/journal/download?GoodsID=cb1shock/2012/002702/010&name=0031-0035j&UserID=131.113.183.243&base=jamas_pdf

    • Related Report
      2013 Final Research Report
  • [Journal Article] 敗血症の診断と治療2013

    • Author(s)
      藤島清太郎
    • Journal Title

      感染防止

      Volume: 23(4) Pages: 1-8

    • Related Report
      2013 Final Research Report
  • [Journal Article] 日本救急医学会Sepsis Registry特別委員会報告:総論Sepsis Registryの概要2013

    • Author(s)
      丸藤哲,藤島清太郎,他
    • Journal Title

      日救急医会誌

      Volume: 24(5) Pages: 247-262

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinical efficacy and safety of intravenous itraconazole in the management of invasive candidiasis in patients of surgery and critical care2012

    • Author(s)
      Takesue Y, Fujishima S, et al
    • Journal Title

      J Infect Chemother

      Volume: 18 Issue: 4 Pages: 515-21

    • DOI

      10.1007/s10156-012-0371-1

    • NAID

      10030948098

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 急性肺損傷(ALI)/急性呼吸窮(促)迫症候群(ARDS)2012

    • Author(s)
      藤島清太郎
    • Journal Title

      Emergency Care

      Volume: 25(7) Pages: 658-63

    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Journal Article] Carbon black nanoparticles enhance bleomycin-induced lung inflammatory and fibrotic changes in mice2011

    • Author(s)
      Kamata H, Fujishima S, et al
    • Journal Title

      Exp Biol Med (Maywood)

      Volume: 236(3) Issue: 3 Pages: 315-24

    • DOI

      10.1258/ebm.2011.010180

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Early administration of sivelestat, the neutrophil elastase inhibitor, in adults for acute lung injury following gastric aspiration2011

    • Author(s)
      Hayashida K, Fujishima S, et al
    • Journal Title

      Shock

      Volume: 36(3) Pages: 223-7

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sepsis診断におけるプロカルシトニンの意義2011

    • Author(s)
      藤島清太郎
    • Journal Title

      化学療法の領域

      Volume: 27(1) Pages: 134-141

    • Related Report
      2013 Final Research Report
  • [Journal Article] 肺血栓塞栓症にみられる呼吸不全2011

    • Author(s)
      藤島清太郎
    • Journal Title

      The lung perspectives

      Volume: 19(1) Pages: 38-45

    • Related Report
      2013 Final Research Report
  • [Journal Article] 侵襲に対する神経・内分泌反応2011

    • Author(s)
      佐藤幸男、藤島清太郎
    • Journal Title

      救急医学

      Volume: 35(7) Pages: 753-6

    • Related Report
      2013 Final Research Report
  • [Journal Article] 急性肺損傷(ALI)、急性呼吸促迫症候群(ARDS)、最近のトピックスと基礎傷病別のエビデンス2011

    • Author(s)
      藤島清太郎
    • Journal Title

      呼吸

      Volume: 30(9) Pages: 761-771

    • Related Report
      2013 Final Research Report
  • [Journal Article] Activated protein Cを介した凝固炎症反応とPROWESS2011

    • Author(s)
      林田敬、藤島清太郎
    • Journal Title

      Thrombosis Medicine

      Volume: 1(2) Pages: 163-169

    • Related Report
      2013 Final Research Report
  • [Journal Article] Early administration of sivelestat, the neutrophil elastase inhibitor, in adults for acute lung injury following gastric aspiration2011

    • Author(s)
      Hayashida K, Fujishima S, Sasao K, Orita T, Toyoda Y, Kitano M, Hori S
    • Journal Title

      Shock

      Volume: 36 Issue: 3 Pages: 223-227

    • DOI

      10.1097/shk.0b013e318225acc3

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Epithelial cell restoration and regeneration in inflammatory lung diseases2011

    • Author(s)
      Fujishima S
    • Journal Title

      Inflammation and Regeneration

      Volume: 31 Issue: 3 Pages: 290-295

    • DOI

      10.2492/inflammregen.31.290

    • NAID

      130004943797

    • ISSN
      1880-8190, 1880-9693
    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 急性肺損傷(ALI)、急性呼吸促迫症候群(ARDS) 最近のトピックスと基礎傷病別のエビデンス2011

    • Author(s)
      藤島清太郎
    • Journal Title

      呼吸

      Volume: 30 Pages: 761-771

    • Related Report
      2011 Research-status Report
  • [Presentation] 急性呼吸不全を呈する救急疾患の診療2014

    • Author(s)
      藤島清太郎
    • Organizer
      第64回日本救急医学会関東地方会教育講演
    • Place of Presentation
      横浜
    • Year and Date
      2014-02-01
    • Related Report
      2013 Final Research Report
  • [Presentation] Acute Respiratory Distress Syndrome : A Case-based Approach for a Heterogenous Pathophysiological Condition2013

    • Author(s)
      Fujishima S
    • Organizer
      18th Congress of the Asian Pacivic Society of Respirology (APSR2013) Coffee Break Seminar 3
    • Place of Presentation
      Yokohama
    • Year and Date
      2013-11-13
    • Related Report
      2013 Final Research Report
  • [Presentation] ARDS:新たな定義と病態の多様性2013

    • Author(s)
      藤島清太郎
    • Organizer
      第41回日本救急医学会総会・学術集会モーニングセミナー8
    • Place of Presentation
      東京
    • Year and Date
      2013-10-23
    • Related Report
      2013 Final Research Report
  • [Presentation] 急性呼吸促迫症候群:画像とバイオマーカーからの病態評価2013

    • Author(s)
      藤島清太郎
    • Organizer
      第23回日本呼吸ケア・リハビリテーション学会学術集会シンポジウム6
    • Place of Presentation
      東京
    • Year and Date
      2013-10-11
    • Related Report
      2013 Final Research Report
  • [Presentation] 敗血症:病態と診断・治療2013

    • Author(s)
      藤島清太郎
    • Organizer
      第145回感染防止研究会
    • Place of Presentation
      東京
    • Year and Date
      2013-07-06
    • Related Report
      2013 Final Research Report
  • [Presentation] 敗血症の疫学・病態と診断2013

    • Author(s)
      藤島清太郎
    • Organizer
      第10回東京消化器外科感染症研究会パネルディスカッション
    • Place of Presentation
      東京
    • Year and Date
      2013-07-06
    • Related Report
      2013 Final Research Report
  • [Presentation] JAAM-SR Basic症例登録結果から見る我が国の敗血症診療の実態2012

    • Author(s)
      藤島清太郎
    • Organizer
      第40回日本救急医学会総会・学術集会教育講演
    • Place of Presentation
      京都
    • Year and Date
      2012-11-14
    • Related Report
      2013 Final Research Report
  • [Presentation] 肺炎球菌が原因と判断された成人急性感染症における予後因子の検討2012

    • Author(s)
      一二三亨、藤島清太郎、他
    • Organizer
      第40回日本救急医学会総会・学術集会ポスター
    • Place of Presentation
      京都
    • Year and Date
      2012-11-14
    • Related Report
      2013 Final Research Report
  • [Presentation] 救急/ICUが抱える感染症の諸問題:重症・劇症感染症の診断と治療2012

    • Author(s)
      藤島清太郎
    • Organizer
      第61回日本感染症学会東日本地方会/第59回日本化学療法学会東日本支部総会合同学会シンポジウム16
    • Place of Presentation
      東京
    • Year and Date
      2012-10-11
    • Related Report
      2013 Final Research Report
  • [Presentation] 全国多施設での院内肺炎の病態と治療に関する実態調査成績2012

    • Author(s)
      河野茂、藤島清太郎、他
    • Organizer
      第61回日本感染症学会東日本地方会/第59回日本化学療法学会東日本支部総会合同学会
    • Place of Presentation
      東京
    • Year and Date
      2012-10-11
    • Related Report
      2013 Final Research Report
  • [Presentation] 呼吸器救急診療のポイント2012

    • Author(s)
      藤島清太郎
    • Organizer
      第22回日本救急放射線研究会ERセミナー
    • Place of Presentation
      長崎
    • Year and Date
      2012-09-29
    • Related Report
      2013 Final Research Report
  • [Presentation] 敗血症とは?2012

    • Author(s)
      藤島清太郎
    • Organizer
      世界敗血症デー記念講演会
    • Place of Presentation
      東京
    • Year and Date
      2012-09-22
    • Related Report
      2013 Final Research Report
  • [Presentation] Quality of care and mortality of severe sepsis and septic shock in Japan2012

    • Author(s)
      Fujishima S, et al
    • Organizer
      American Thoracic Society (ATS) 2012 International Conference
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2012-05-23
    • Related Report
      2013 Final Research Report
  • [Presentation] 急性呼吸促迫症候群:エビデンスに基づく治療の個別化の試み2012

    • Author(s)
      藤島清太郎
    • Organizer
      第27回日本Shock学会総会
    • Place of Presentation
      東京
    • Year and Date
      2012-05-12
    • Related Report
      2013 Final Research Report
  • [Presentation] 第86回日本感染症学会・学術講習会ランチョンセミナー92012

    • Author(s)
      藤島清太郎
    • Organizer
      感染症BiomarkerとしてのProcalcitonin
    • Place of Presentation
      長崎
    • Year and Date
      2012-04-26
    • Related Report
      2013 Final Research Report
  • [Presentation] 呼吸器疾患における肺循環障害の治療と今後の展望:ARDSにおける肺循環障害と治療2012

    • Author(s)
      藤島清太郎
    • Organizer
      第52回日本呼吸器学会学術講演会シンポジウム2
    • Place of Presentation
      神戸
    • Year and Date
      2012-04-20
    • Related Report
      2013 Final Research Report
  • [Presentation] 急性呼吸促迫症候群:新たな診断基準と個別化治療戦略2012

    • Author(s)
      藤島清太郎
    • Organizer
      第52回日本呼吸器学会学術講演会イブニングシンポジウム6
    • Place of Presentation
      神戸
    • Year and Date
      2012-04-20
    • Related Report
      2013 Final Research Report
  • [Presentation] Successful treatment of disseminated intravascular coagulation with recombinant human soluble thrombomodulin in a patient with neuroleptic malignant syndrome2012

    • Author(s)
      Hayashida K, Fujishima S, et al
    • Organizer
      41st Critical Care Congress
    • Place of Presentation
      Houston, USA
    • Year and Date
      2012-02-06
    • Related Report
      2013 Final Research Report
  • [Presentation] Interleukin-17A in the pathogenesis of elastase-induced emphysema in mice2012

    • Author(s)
      Kamiishi N, Fujishima S, et al
    • Organizer
      European Respiratory Society 2012 Annual Congress
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2013 Final Research Report
  • [Presentation] Japanese Association for Acute Medicine Sepsis Registry Special Committee. Quality of care and mortality of severe sepsis and septic shock in Japan2012

    • Author(s)
      Fujishima S, Gando S, Saito D, Mayumi T, Kushimoto S, Shiraishi S, Ogura H, Takuma K, Kotani J, Ikeda H, Yamashita N, Suzuki K, Tsuruta R, et al.
    • Organizer
      American Thoracic Society (ATS) 2012 International Conference
    • Place of Presentation
      米国 San Francisco
    • Related Report
      2012 Research-status Report
  • [Presentation] ARDSにおける肺循環障害と治療2012

    • Author(s)
      藤島清太郎
    • Organizer
      第52回日本呼吸器学会学術講演会シンポジウム2
    • Place of Presentation
      神戸
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 急性呼吸促迫症候群:エビデンスに基づく治療の個別化の試み2012

    • Author(s)
      藤島清太郎
    • Organizer
      第27回日本Shock学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 救急/ICUが抱える感染症の諸問題 重症・劇症感染症の診断と治療2012

    • Author(s)
      藤島清太郎
    • Organizer
      第61回日本感染症学会東日本地方会/第59回日本化学療法学会東日本支部総会合同学会シンポジウム
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] LI/ARDSに関する最近のトピックスと基礎傷病別のエビデンス2011

    • Author(s)
      藤島清太郎
    • Organizer
      第21回日本呼吸ケア・リハビリテーション学会
    • Place of Presentation
      松本
    • Year and Date
      2011-11-03
    • Related Report
      2013 Final Research Report
  • [Presentation] 日本救急医学会Sepsis Registry特別委員会.わが国の多施設共同調査研究、レジストリーの成果とこれから日本救急医学会Sepsis Registry Basic版によるデータ収集と診療の質の評価2011

    • Author(s)
      藤島清太郎、他
    • Organizer
      第39回日本救急医学会総会・学術集会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-10-20
    • Related Report
      2013 Final Research Report
  • [Presentation] わが国の多施設共同調査研究、レジストリーの成果とこれから日本救急医学会Sepsis Registry Basic版によるデータ収集と診療の質の評価2011

    • Author(s)
      小倉裕司、藤島清太郎、他
    • Organizer
      第39回日本救急医学会総会・学術集会教育セミナー
    • Place of Presentation
      東京
    • Year and Date
      2011-10-20
    • Related Report
      2013 Final Research Report
  • [Presentation] 侵襲性肺炎球菌感染症の臨床病態に関する後ろ向き検討2011

    • Author(s)
      一二三亨、藤島清太郎、他
    • Organizer
      第39回日本救急医学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-19
    • Related Report
      2013 Final Research Report
  • [Presentation] 感染症biomarkerとしてのprocalcitonin2011

    • Author(s)
      藤島清太郎
    • Organizer
      第39回日本救急医学会総会・学術集会教育セミナー
    • Place of Presentation
      東京
    • Year and Date
      2011-10-18
    • Related Report
      2013 Final Research Report
  • [Presentation] ALI/ARDSに関する最近のトピックスと基礎傷病別のエビデンス2011

    • Author(s)
      藤島清太郎
    • Organizer
      第21回日本呼吸ケア・リハビリテーション学会(招待講演)
    • Place of Presentation
      長野県松本文化会館(長野県)
    • Related Report
      2011 Research-status Report
  • [Presentation] 1. Fujishima S. Acute Respiratory Distress Syndrome: A Case-based Approach for a Heterogenous Pathophysiological Condition.

    • Author(s)
      Fujishima S.
    • Organizer
      18th Congress of the Asian Pacivic Society of Respirology
    • Place of Presentation
      横浜
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 敗血症~病態と診断・治療~

    • Author(s)
      藤島清太郎
    • Organizer
      第145回感染防止研究会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 敗血症の疫学・病態と診断

    • Author(s)
      藤島清太郎
    • Organizer
      第10回東京消化器外科感染症研究会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 急性呼吸促迫症候群:画像とバイオマーカーからの病態評価

    • Author(s)
      藤島清太郎
    • Organizer
      第23回日本呼吸ケア・リハビリテーション学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] ARDS:新たな定義と病態の多様性

    • Author(s)
      藤島清太郎
    • Organizer
      第41回日本救急医学会総会・学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] 今日の治療指針2013年版:急性呼吸促迫症候群2013

    • Author(s)
      藤島清太郎
    • Publisher
      医学書院
    • Related Report
      2013 Final Research Report
  • [Book] 今日の治療看護:急性肺損傷・急性呼吸促迫症候群2013

    • Author(s)
      藤島清太郎
    • Publisher
      南江堂
    • Related Report
      2013 Final Research Report
  • [Book] 別冊・医学の歩み:呼吸器疾患state of arts Ver. 6:急性呼吸促迫症候群(ARDS)の病態2013

    • Author(s)
      藤島清太郎
    • Publisher
      医歯薬出版
    • Related Report
      2013 Final Research Report
  • [Book] 今日の処方改訂第5版:急性呼吸促迫症候群(ARDS)2013

    • Author(s)
      藤島清太郎
    • Publisher
      南江堂
    • Related Report
      2013 Final Research Report
  • [Book] 医療スタッフのための日本版敗血症診療ガイドライン活用マニュアル:敗血症の病態2013

    • Author(s)
      藤島清太郎
    • Publisher
      学研メディカル秀潤社
    • Related Report
      2013 Final Research Report
  • [Book] 呼吸器疾患 state of arts Ver. 6:急性呼吸促迫症候群(ARDS)の病態2013

    • Author(s)
      藤島清太郎
    • Total Pages
      4
    • Publisher
      医歯薬出版
    • Related Report
      2013 Annual Research Report
  • [Book] 今日の治療指針2013年版2013

    • Author(s)
      藤島清太郎
    • Total Pages
      2
    • Publisher
      急性呼吸促迫症候群
    • Related Report
      2012 Research-status Report
  • [Book] 別冊・医学の歩み 呼吸器疾患 state of arts Ver. 62013

    • Author(s)
      藤島清太郎
    • Total Pages
      4
    • Publisher
      急性呼吸促迫症候群(ARDS)の病態
    • Related Report
      2012 Research-status Report
  • [Book] 今日の救急指針第2版2012

    • Author(s)
      藤島清太郎
    • Total Pages
      7
    • Publisher
      急性呼吸不全、慢性呼吸不全の急性増悪
    • Related Report
      2012 Research-status Report
  • [Book] 感染症専門医テキスト第I部解説編:全身管理と対症療法2011

    • Author(s)
      藤島清太郎
    • Publisher
      南江堂
    • Related Report
      2013 Final Research Report
  • [Book] 救急診療指針改定第4版2011

    • Author(s)
      藤島清太郎
    • Total Pages
      6
    • Publisher
      へるす出版
    • Related Report
      2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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