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Indication of induced hyperthermia using somatosensory evoked potential in patients presenting with post-cardiac arrest syndrome

Research Project

Project/Area Number 23592685
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Emergency medicine
Research InstitutionNihon University

Principal Investigator

MORIYA Takashi  日本大学, 医学部, 講師 (50267069)

Co-Investigator(Kenkyū-buntansha) SUGITA Atsunori  日本大学, 医学部, 助手 (70599745)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Keywordsinduced hypothermia / 低体温療法 / 体性感覚誘発電位 / 聴性脳幹誘発電位 / 予後評価
Research Abstract

Patients likely to remain in coma in spite of a return of spontaneous circulation were examined for the presence or absence of somatosensory evoked potential (SSEP) N20 before the induction of hypothermia. Prognosis was poor for all of the patients without SSEP N20. Patients with SSEP N20, on other hand, showed improvement of consciousness at a high rate. An examination to determine the presence or absence of SSEP N20 before the induction of hypothermia may be a reliable and efficient way to select cases in whom the hypothermia will be effective. The measurement of SSEP N20 before induced hypothermia and at 24 hours after a return of spontaneous circulation may be very useful for identifing the patients in whom a favorable outcome can be expected after induced hypothermia. The measurement of SSEP N20 at 24hours after a return of spontaneous circulation may allow us to identify the patients not likely to benefit from induced hypothermia.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (33 results)

All 2014 2013 2012 2011 Other

All Journal Article (10 results) (of which Peer Reviewed: 4 results) Presentation (16 results) Book (4 results) Remarks (3 results)

  • [Journal Article] Shorter time until return of spontaneous circulation is the only independent factor for a good neurological outcome in patients with post-cardiac arrest syndrome2013

    • Author(s)
      Komatsu T、Kinoshita K、Sakurai A、Moriya T、Yamaguchi J、Sugita A、Kogawa R、Tanjoh K
    • Journal Title

      Emerg Med J

      Volume: 31 Issue: 7 Pages: 549-555

    • DOI

      10.1136/emermed-2013-202457

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 心停止後症候群の体温管理2013

    • Author(s)
      守谷俊
    • Journal Title

      救急医学

      Volume: 37巻 Pages: 1091-1095

    • Related Report
      2013 Final Research Report
  • [Journal Article] Effects of bag-mask versus advanced airway ventilation for patients undergoing prolonged cardiopulmonary resuscitation in pre-hospital setting2013

    • Author(s)
      Nagao T、Kinoshita K、Sakurai A、Yamaguchi J、Furukawa M、Utagawa A、Moriya T、Azuhata T、Tanjoh K
    • Journal Title

      The Journal of Emergency Medicine

      Volume: 42巻

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Shorter time until return of spontaneous circulation is the only independent factor for a good neurological outcome in patients with postcardiac arrest syndrome.2013

    • Author(s)
      Komatsu T., Kinoshita K., Sakurai A., Moriya T., Yamaguchi J., Sugita A., Kogawa R., Tanjoh K
    • Journal Title

      Emerg Med J.

      Volume: emermed-2013 Pages: 202457-202457

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 心停止後症候群の体温管理2013

    • Author(s)
      守谷 俊
    • Journal Title

      救急医学

      Volume: 37 Pages: 1091-1095

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Effects of bag-mask versus advanced airway ventilation for patients undergoing prolonged cardiopulmonary resuscitation in pre-hospital setting.2013

    • Author(s)
      Nagao T, Kinoshita K, Sakurai A, Yamaguchi J, Furukawa M, Utagawa A, Moriya T, Azuhata T, Tanjoh K
    • Journal Title

      The Journal of Emergency Medicine

      Volume: 42 Issue: 2 Pages: 162-170

    • DOI

      10.1016/j.jemermed.2011.02.020

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 急性心筋梗塞の治療戦略脳低温療法2011

    • Author(s)
      守谷俊
    • Journal Title

      日本臨牀

      Volume: 69巻

    • Related Report
      2013 Final Research Report
  • [Journal Article] 蘇生後脳症の管理2011

    • Author(s)
      守谷俊
    • Journal Title

      レジデント

      Volume: 4巻(7)

    • Related Report
      2013 Final Research Report
  • [Journal Article] 急性心筋梗塞の治療戦略 脳低温療法2011

    • Author(s)
      守谷 俊
    • Journal Title

      日本臨牀

      Volume: 69 Pages: 186-188

    • Related Report
      2011 Research-status Report
  • [Journal Article] 蘇生後脳症の管理2011

    • Author(s)
      守谷 俊
    • Journal Title

      レジデント

      Volume: 4(7) Pages: 156-165

    • Related Report
      2011 Research-status Report
  • [Presentation] Relationship between the findings of time course of short-latency somatosensory evoked potential and prognosis in patients after cardiac arrest and return of spontaneous circulation2014

    • Author(s)
      Moriya T
    • Organizer
      41th Society of Critical Care Congress
    • Place of Presentation
      San Francisco
    • Year and Date
      2014-01-09
    • Related Report
      2013 Final Research Report
  • [Presentation] Relationship between the findings of time course of short-latency somatosensory evoked potential and prognosis in patients after cardiac arrest and return of spontaneous circulation2014

    • Author(s)
      Moriya T., Ihara S., Sakurai A., Kinoshita K. and Tanjoh K.
    • Organizer
      40th Sciety of Critical Care Congress
    • Place of Presentation
      SanFrancisco
    • Related Report
      2013 Annual Research Report
  • [Presentation] 非心原性心停止症候群における脳低温療法の有効性の検討2013

    • Author(s)
      小松智英
    • Organizer
      第41回日本救急医学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2013-10-21
    • Related Report
      2013 Final Research Report
  • [Presentation] Importance of SSEP as a predictor of favorable outcome in patients at 24 hours after cardiac arrest2013

    • Author(s)
      Moriya T
    • Organizer
      The 7^<th> Asian Conference on Emergency medicine
    • Place of Presentation
      Tokyo
    • Year and Date
      2013-10-13
    • Related Report
      2013 Final Research Report
  • [Presentation] Short-latency somatosensory evoked potential as predictor of favorable outcome in patients immediately after cardiac arrest and return of spontaneous circulation2013

    • Author(s)
      Moriya T
    • Organizer
      40th Society of Critical Care Congress
    • Place of Presentation
      Puerto Rico
    • Year and Date
      2013-01-19
    • Related Report
      2013 Final Research Report
  • [Presentation] Importance of SEEP as a predictor of favorable outcome in patients at 24 hours after cardiac arrest2013

    • Author(s)
      Moriya T., Sakurai A., Kinoshita K. and Tanjoh K.
    • Organizer
      The 7th Asian Conference on Emergency Medicine
    • Place of Presentation
      Tokyo
    • Related Report
      2013 Annual Research Report
  • [Presentation] 非心原性心停止症候群における脳低温療法の有効性の検討2013

    • Author(s)
      小松智英,櫻井 淳,守谷 俊,木下浩作,丹正勝久
    • Organizer
      第41回日本救急医学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Short-latency somatosensory evoked potential as predictor of favorable outcome in patients immediate after cardiac arrest and return of spontaneous circulation2013

    • Author(s)
      Moriya T, Ihara S, Sakurai A, Kinoshita K, Tanjoh K.
    • Organizer
      40th Sciety of Critical Care Congress
    • Place of Presentation
      プエルトリコ
    • Related Report
      2012 Research-status Report
  • [Presentation] 心停止後症候群症例に対する体性感覚誘発電位の早期評価と補助療法の可能性2012

    • Author(s)
      守谷俊
    • Organizer
      第40回日本救急医学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2012-11-13
    • Related Report
      2013 Final Research Report
  • [Presentation] 心停止蘇生後の脳低温療法適応に関する早期SEPの臨床的意義2012

    • Author(s)
      守谷俊
    • Organizer
      第42回日本臨床神経生理学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-11-08
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] 心停止後症候群における神経学的転帰改善に必要な救急医療体制2012

    • Author(s)
      小松智英
    • Organizer
      第15回日本臨床救急医学会総会・学術集会
    • Place of Presentation
      熊本
    • Year and Date
      2012-06-16
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] 心停止後症候群症例に対する体性感覚誘発電位の早期評価と補助療法の可能性2012

    • Author(s)
      守谷 俊,櫻井 淳,木下浩作,丹正勝久
    • Organizer
      第40回日本救急医学会総会・学術集会
    • Place of Presentation
      京都
    • Related Report
      2012 Research-status Report
  • [Presentation] The importance of the time that collapses before spontaneous circulation is established following a cardiac arrest outside hospital2011

    • Author(s)
      Sakurai A
    • Organizer
      Brain Edema 2011
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-10-22
    • Related Report
      2013 Final Research Report
  • [Presentation] ECMOを用いた集中治療により救命し良好な経過を得ることが出来た2例2011

    • Author(s)
      伊原慎吾
    • Place of Presentation
      東京
    • Year and Date
      2011-07-30
    • Related Report
      2013 Final Research Report
  • [Presentation] ECMOを用いた集中治療により救命し良好な経過を得ることが出来た2例2011

    • Author(s)
      伊原慎吾,古川力丸,桑名 司,守谷 俊,木下浩作,丹正勝久
    • Organizer
      第20回日本集中治療医学会関東甲信越地方会
    • Place of Presentation
      東京:アルカディア市ヶ谷
    • Related Report
      2011 Research-status Report
  • [Presentation] The importance of the time that elapses before spontaneous circulation is established following a cardiac arrest outside hospital2011

    • Author(s)
      Sakurai A, Kinoshita K, Moriya T, Yamaguchi J, Furukawa M, Noda A, Kogawa R, Komatsu T, Tanjoh K
    • Organizer
      Brain Edema 2011
    • Place of Presentation
      Tokyo:Nihon Daigaku Kaikan
    • Related Report
      2011 Research-status Report
  • [Book] 心停止蘇生後症候群に対する神経集中治療2014

    • Author(s)
      守谷俊
    • Publisher
      総合医学社
    • Related Report
      2013 Final Research Report
  • [Book] 心停止蘇生後症候群に対する神経集中治療2014

    • Author(s)
      守谷 俊
    • Total Pages
      257
    • Publisher
      総合医学社
    • Related Report
      2013 Annual Research Report
  • [Book] ER診療の実際2013

    • Author(s)
      守谷俊
    • Publisher
      医学出版
    • Related Report
      2013 Final Research Report
  • [Book] ER診療の実際2013

    • Author(s)
      守谷 俊
    • Total Pages
      270
    • Publisher
      医学出版
    • Related Report
      2013 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.nihon-u.ac.jp/department/eccm/

    • Related Report
      2013 Final Research Report
  • [Remarks] 日本大学医学部 救急医学系 救急集中治療医学分野 研究業績

    • URL

      http://www.med.nihon-u.ac.jp/department/eccm/translation.html

    • Related Report
      2013 Annual Research Report
  • [Remarks] 心停止蘇生後の脳低温療法施行前の電気生理学的検査のうち、大脳皮質機能を反映するSSEP N20陽性の所見は予後良好な結果が期待できる所見として有用である可能性が高い。

    • Related Report
      2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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