| Project/Area Number |
23592699
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
YOSHIDA Atsushi 大阪大学, 歯学研究科(研究院), 教授 (90201855)
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| Co-Investigator(Kenkyū-buntansha) |
KATO Takafumi 大阪大学, 大学院歯学研究科, 講師 (50367520)
ONO Takahiro 大阪大学, 大学院歯学研究科, 准教授 (30204241)
MORITANI Masayuki 森ノ宮医療大学, 保健医療学部, 教授 (80303981)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 顎運動 / 三叉神経運動核 / 運動ニューロン / 大脳皮質 / 脳 / 神経 / 解剖 / 歯学 / 咀嚼 / 顎 / 抑制性ニューロン / 頤 |
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| Research Abstract |
Electrical stimulation of the primary somatosensory cortex and the lateral part of the prefrontal cortex (insular cortex) as well as the lateral part of the agranular cortex induced jaw-movements which are specific for the cortical location stimulated. However, stimulation of the medial part of the agranular cortex did not induce any jaw-movements. These cortical areas sent direct projections to the trigeminal sensory nuclear complex and the reticular formation around the trigeminal motor nucleus both of which include excitatory and/or inhibitory premotoneurons. Note that such premotoneurons were also found in the solitary tract nucleus.
These results may indicate that several indirect projections from the cerebral cortical areas to the trigeminal motor nucleus via its premotoneurons are involved in the induction of the characteristic jaw-movements, and the jaw-movement disorders are attributed to the disorders of the indirect projection systems from the cerebral cortical areas.
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