• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Analysis of virulence regulatory mechanism of group A streptococcal ncRNA

Research Project

Project/Area Number 23592700
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Morphological basic dentistry
Research InstitutionOsaka University

Principal Investigator

NAKATA Masanobu  大阪大学, 歯学研究科(研究院), 准教授 (90444497)

Co-Investigator(Kenkyū-buntansha) KAWABATA Shigetada  大阪大学, 歯学研究科, 教授 (50273694)
TERAO Yutaka  新潟大学, 医歯学系, 教授 (50397717)
SUMITOMO Tomoko  大阪大学, 歯学研究科, 助教 (50423421)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
KeywordsA群レンサ球菌 / ncRNA / 細菌 / レンサ球菌 / non-coding RNA
Research Abstract

Streptococcus pyogenes regulates expression of virulence factors in infection sites, and causes purulent diseases. Recently, transcriptional and translational regulations by RNA have been noted. In this study, non-coding RNA candidates were searched in Streptococcus pyogenes, and target mRNAs of non-coding RNAs were investigated using constructed mutant strains. Moreover, regarding the essential gene encoding a transcriptional regulator, an riboswitch was introduced upstream of the gene, and the function of the essential gene was analysed. When the translation rate of the gene was reduced in the mutant strain, the growth was markedly inhibited. Moreover, the mutant showed an abnormal cellular morphology and irregular superficial structure. Our results indicate that riboswitch-based translational control is useful for analysis of essential factors of Streptococcus pyogens.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (75 results)

All 2014 2013 2012 2011 Other

All Journal Article (23 results) (of which Peer Reviewed: 23 results,  Open Access: 1 results) Presentation (46 results) (of which Invited: 1 results) Book (5 results) Remarks (1 results)

  • [Journal Article] Hydrogen peroxide contributes to the epithelial cell death induced by the oral mitis group of streptococci.2014

    • Author(s)
      Okahashi N, Sumitomo T, Nakata M, Sakurai A, Kuwata H, and Kawabata S.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 1 Pages: 88136-88136

    • DOI

      10.1371/journal.pone.0088136

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Crystal structure of PfbA, a surface adhesion of Streptococcus pneumoniae, provides hints into its interaction with fibronectin2014

    • Author(s)
      Beulin DS, Yamaguchi M, Kawabata S, and Ponnuraj K
    • Journal Title

      Int J Biol Macromol

      Volume: 64 Pages: 168-173

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Streptococcus pneumoniae invades erythrocytes and utilizes them to evade human innate immunity.2013

    • Author(s)
      Yamaguchi M, Terao Y, Mori-Yamaguchi Y, Domon H, Sakaue Y , Yagi T, Nishino K, Yamaguchi A, Nizet V, Kawabata S.
    • Journal Title

      PLoS One

      Volume: VOL.8 Issue: 10 Pages: 77282-77282

    • DOI

      10.1371/journal.pone.0077282

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cysteine proteinase from Streptococcus pyogenes enables evasion of innate immunity via degradation of complement factors2013

    • Author(s)
      Honda-Ogawa M, Ogawa T, Terao Y, Sumitomo T, Nakata M, Ikebe K, Maeda Y, and Kawabata S
    • Journal Title

      J Biol Chem

      Volume: 288 Issue: 22 Pages: 15854-15864

    • DOI

      10.1074/jbc.m113.469106

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Group A streptococcal cysteine protease cleaves epithelial junctions and contributes to bacterial translocation2013

    • Author(s)
      Sumitomo T, Nakata M, Higashino M, Terao Y, and Kawabata S
    • Journal Title

      J Biol Chem

      Volume: 288 Issue: 19 Pages: 13317-13324

    • DOI

      10.1074/jbc.m113.459875

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hydrogen peroxide produced by oral streptococci induces cell death of macrophage.2013

    • Author(s)
      Okahashi N, Nakata M, Sumitomo T, Terao Y, Kawabata S.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 5 Pages: 62563-62563

    • DOI

      10.1371/journal.pone.0062563

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] MicroRNA fragments derived from Streptococcus pyogenes enable activation of neutrophil phagocytosis : in vitro study2013

    • Author(s)
      Ogawa T, Terao Y, Honda-Ogawa M, Hashimoto S, Ikebe K, Maeda Y, and Kawabata S
    • Journal Title

      Microbes Infect

      Volume: 15 Issue: 3 Pages: 212-218

    • DOI

      10.1016/j.micinf.2012.11.009

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Cysteine proteinase from Streptococcus pyogenes enables to evade innate immunity via degradation of complement factors.2013

    • Author(s)
      Honda-Ogawa M, Ogawa T, Terao Y, Sumitomo T, Nakata M, Ikebe K, Maeda Y, and Kawabata S.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 印刷中

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Group A streptococcal cysteine protease cleaves epithelial junctions and contributes to bacterial translocation.2013

    • Author(s)
      Sumitomo T, Nakata M, Higashino M, Terao Y, and Kawabata S.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 印刷中

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Hydrogen peroxide produced by oral streptococci induces cell death of macrophage.2013

    • Author(s)
      Okahashi N, Nakata M, Sumitomo T, Terao Y, and Kawabata S.
    • Journal Title

      PLoS One

      Volume: 印刷中

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pieiotropic virulence factor - Streptococcus pyogenes fibronectin-binding proteins2013

    • Author(s)
      Yamaguchi M, Terao Y, Kawabata S
    • Journal Title

      Cellular Microbiology

      Volume: (in press) Issue: 4 Pages: 503-511

    • DOI

      10.1111/cmi.12083

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Evolution of cariogenic character in Streptococcus mutans: horizontal transmission of glycosyl hydrolase family 70 genes.2012

    • Author(s)
      Hoshino T
    • Journal Title

      Scientific Reports

      Volume: 2 Issue: 1 Pages: 518-518

    • DOI

      10.1038/srep00518

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Group A Streptococcus adheres to pharyngeal epithelial cells with salivary proline-rich proteins via GrpE chaperone protein2012

    • Author(s)
      Murakami J, Terao Y, Morisaki I, Hamada S, and Kawabata S
    • Journal Title

      J Biol Chem

      Volume: 287 Issue: 26 Pages: 22266-22275

    • DOI

      10.1074/jbc.m112.350082

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] α-enolase of Streptococcus pneumoniae induces formation of neutrophil extracellular traps2012

    • Author(s)
      Mori Y., Yamaguchi M., Terao Y., Hamada S., Ooshima T., Kawabata S.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 287 Issue: 13 Pages: 10472-10481

    • DOI

      10.1074/jbc.m111.280321

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of T6 pili in biofilm formation by serotype M6 Streptococcus pyogenes2012

    • Author(s)
      Kimura KR, Nakata M, Sumitomo T, Kreikemeyer B, Podbielski A, Terao Y, and Kawabata S
    • Journal Title

      J Bacteriol

      Volume: 194 Issue: 4 Pages: 804-812

    • DOI

      10.1128/jb.06283-11

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] S-carboxymethylcysteine inhibits adherence of Streptococcus pneumoniae to human alveolar epithelial cells2012

    • Author(s)
      Sumitomo, T., Nakata, M., Yamaguchi, M., Terao, Y., Kawabata S.
    • Journal Title

      Journal of Medical Microbiology

      Volume: 61 Issue: 1 Pages: 101-108

    • DOI

      10.1099/jmm.0.033688-0

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Novel Epitopic Region of Glucosyltransferase B from Streptococcus mutans2012

    • Author(s)
      Tomonori Hoshino, Yoshio Kondo, Kan Saito, Yutaka Terao, Nobuo Okahashi, Shigetada Kawabata, and Taku Fujiwara, Shigetada Kawabata, and Taku Fujiwara
    • Journal Title

      Clinical and Vaccine Immunology

      Volume: 18(9) Issue: 9 Pages: 1552-1561

    • DOI

      10.1128/cvi.05041-11

    • NAID

      120006985025

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Identification and characterization of a collagen-binding protein, Cbm, in Streptococcus mutans.2012

    • Author(s)
      Nomura R
    • Journal Title

      Molecular Oral Microbiology

      Volume: 27 Issue: 4 Pages: 308-323

    • DOI

      10.1111/j.2041-1014.2012.00649.x

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Assembly mechanism of FCT region type 1 pili in serotype M6 Streptococcus pyogenes2011

    • Author(s)
      Nakata M, Kimura KR, Sumitomo T, Wada S, Sugauchi A, Oiki E, Higashino M, Kreikemeyer B, Podbielski A, Okahashi N, Hamada S, Isoda R, Terao Y, and Kawabata S
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 43 Pages: 37566-37577

    • DOI

      10.1074/jbc.m111.239780

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Streptococcus sanguinis induces foam cell formation and cell death of macrophages in association with production of reactive oxygen species2011

    • Author(s)
      Okahashi N, et al
    • Journal Title

      FEMS Microbiology Letters

      Volume: 323巻 Issue: 2 Pages: 164-170

    • DOI

      10.1111/j.1574-6968.2011.02375.x

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Biofilm formation or internalization into epithelial cells enable Streptococcus pyogenes to evade antibiotic eradication in patients with pharyngitis2011

    • Author(s)
      Ogawa T, Terao Y, Okuni H, Ninomiya K, Sakata H, Ikebe K, Maeda Y, and Kawabata S
    • Journal Title

      Microb Pathog

      Volume: 51 Pages: 58-68

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Epidemiological characterization of Streptococcus pyogenes isolated from patients with multiple onsets of pharyngitis2011

    • Author(s)
      Ogawa T, Terao Y, Sakata H, Ohkuni H, Ninomiya K, Ikebe K, Maeda Y, and Kawabata S
    • Journal Title

      FEMS Microb Lett

      Volume: 318 Issue: 2 Pages: 143-151

    • DOI

      10.1111/j.1574-6968.2011.02252.x

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pili of oral Streptococcus sanguinis bind to salivary amylase and promote the biofilm formation2011

    • Author(s)
      Okahashi N, et al
    • Journal Title

      Microbial Pathogenesis

      Volume: 50巻 Issue: 3-4 Pages: 148-154

    • DOI

      10.1016/j.micpath.2011.01.005

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Streptococcus pyogenesが産生するFCT3型線毛の発現調節機構の解析2014

    • Author(s)
      中田匡宣,住友倫子,浜田茂幸,川端重忠
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京都江戸川区・タワーホール船堀
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Group A Streptococcus translacates across epithelial barrier via tricellular tight junctions2014

    • Author(s)
      住友倫子,東野美晴,中田匡宣,川端重忠
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京都江戸川区・タワーホール船堀
    • Related Report
      2013 Final Research Report
  • [Presentation] Wall-anchored nuclease of Streptococcus sanguinis contributes to evasion of innate immunity2014

    • Author(s)
      森田知里,住岡龍一,中田匡宣,住友倫子,岡橋暢夫,浜田茂幸,川端重忠
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京都江戸川区・タワーホール船堀
    • Related Report
      2013 Final Research Report
  • [Presentation] Streptococcus pyogenesのC3様ADPリボシルトランスフェラーゼSpyAの機能解析2014

    • Author(s)
      毛利泰士,住友倫子,中田匡宣,川端重忠
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京都江戸川区・タワーホール船堀
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] 口腔レンサ球菌が産生する課酸素水素がマクロファージの細胞死を誘導する2014

    • Author(s)
      岡橋暢夫,中田匡宣,住友倫子,寺尾豊,川端重忠
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京都江戸川区・タワーホール船堀
    • Related Report
      2013 Final Research Report
  • [Presentation] Wall-anchored nuclease of Streptococcus sanguinis contributes to evasion of innate immunity.2014

    • Author(s)
      森田知里,住岡龍一,中田匡宣,住友倫子,岡橋暢夫,浜田茂幸,川端重忠.
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京都江戸川区・タワーホール船堀
    • Related Report
      2013 Annual Research Report
  • [Presentation] 口腔レンサ球菌が産生する過酸化水素がマクロファージの細胞死を誘導する.2014

    • Author(s)
      岡橋暢夫,中田匡宣,住友倫子,寺尾豊,川端重忠.
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京都江戸川区・タワーホール船堀
    • Related Report
      2013 Annual Research Report
  • [Presentation] Streptococcus sanguinisが産生するヌクレアーゼの機能解析2013

    • Author(s)
      森田知里,住岡龍一,中田匡宣,岡橋暢夫,住友倫子,川端重忠
    • Organizer
      第66回日本細菌学会関西支部総会
    • Place of Presentation
      吹田市・大阪大学微生物病研究所谷口記念講堂
    • Year and Date
      2013-11-16
    • Related Report
      2013 Final Research Report
  • [Presentation] A群レンサ球菌は宿主カルパインの活性化を介して上皮バリアを突破する2013

    • Author(s)
      住友倫子,中田匡宣,寺尾豊,川端重忠
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山市・岡山コンベンションセンター
    • Related Report
      2013 Final Research Report
  • [Presentation] Streptococcus sanguinisの菌体表層ヌクレアーゼは自然免疫からの回避に寄与する2013

    • Author(s)
      森田知里,住岡龍一,中田匡宣,岡橋暢夫,住友倫子,川端重忠
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山市・岡山コンベンションセンター
    • Related Report
      2013 Final Research Report
  • [Presentation] Mode of expression and assembly mechanism of Group A Streptococcal pili2013

    • Author(s)
      Nakata M, Kawabata S
    • Organizer
      The 12th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji Yumebutai International Conference Center, Awaji, Hyogo, Japan
    • Related Report
      2013 Final Research Report
  • [Presentation] Group A streptococcal pyrogenic exotoxin B cleaves epithelial junctions and contributes to bacterial translocation2013

    • Author(s)
      Sumitomo T, Nakata M, Higashino M, Terao Y, and Kawabata S
    • Organizer
      113th General Meeting of American Society for Microbiology
    • Place of Presentation
      Colorado Convention Center, Denver, CO, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] A群レンサ球菌の上皮バリア突破機構に関与する宿主プロテアーゼの解析2013

    • Author(s)
      住友倫子,中田匡宣,寺尾豊,川端重忠
    • Organizer
      第22回Lancefieldレンサ球菌研究会
    • Place of Presentation
      東京都港区・ホテル島根イン青山
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Assembly mechanism of T6 pili and its involvement in biofilm formation2013

    • Author(s)
      Nakata M, Sumitomo T, and Kawabata S
    • Organizer
      GAS Infections 2013
    • Place of Presentation
      Residenza di Ripetta, Roma Italy
    • Related Report
      2013 Final Research Report
  • [Presentation] Streptococcus pyogenesが産生するFCT3型線毛の細胞壁架橋機構の解析2013

    • Author(s)
      中田匡宣,住友倫子,寺尾豊,浜田茂幸,川端重忠
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉市・幕張メッセ
    • Related Report
      2013 Final Research Report
  • [Presentation] A群レンサ球菌のシステインプロテアーゼSpeBおよびSib35による上皮細胞間接着分子の分解2013

    • Author(s)
      住友倫子,東野美晴,小南明里,中田匡宣,寺尾豊,川端重忠
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉市・幕張メッセ
    • Related Report
      2013 Final Research Report
  • [Presentation] Streptococcus pyogenesのシステインプロテアーゼSpeBによる補体免疫系回避機構2013

    • Author(s)
      本多真理子,寺尾豊,住友倫子,中田匡宣,川端重忠
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉市・幕張メッセ
    • Related Report
      2013 Final Research Report
  • [Presentation] Streptococcus sanguinisの細胞壁架橋型ヌクレアーゼの機能解析2013

    • Author(s)
      森田知里,住岡龍一,中田匡宣,岡橋暢夫,本多真理子,住友倫子,川端重忠
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉市・幕張メッセ
    • Related Report
      2013 Final Research Report
  • [Presentation] A群レンサ球菌は宿主カルパインの活性化を介して上皮バリアを突破する.2013

    • Author(s)
      住友倫子,中田匡宣,寺尾豊,川端重忠.
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山市・岡山コンベンションセンター
    • Related Report
      2013 Annual Research Report
  • [Presentation] Group A streptococcal pyrogenic exotoxin B cleaves epithelial junctions and contributes to bacterial translocation.2013

    • Author(s)
      Sumitomo T, Nakata M, Higashino M, Terao Y, and Kawabata S.
    • Organizer
      113th General Meeting of American Society for Microbiology
    • Place of Presentation
      Colorado Convention Center, Denver, CO, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Cell wall anchoring mechanism of FCT region type 3 pili in Streptococcus pyogenes.2013

    • Author(s)
      中田匡宣,住友倫子,寺尾豊, 浜田茂幸,川端重忠.
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ,千葉市, 千葉県
    • Related Report
      2012 Research-status Report
  • [Presentation] Group A streptococcal cycteine proteases, SpeB and Sib35, cleave epithelial junctions.2013

    • Author(s)
      住友倫子,東野美晴,小南明里, 中田匡宣,寺尾豊,川端重忠.
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ,千葉市, 千葉県
    • Related Report
      2012 Research-status Report
  • [Presentation] Molocular mechanisms of complement evasion by Streptococcus pyogenes cysteine protease SpeB.2013

    • Author(s)
      本多真理子,寺尾豊,住友倫子, 中田匡宣,川端重忠.
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ,千葉市, 千葉県
    • Related Report
      2012 Research-status Report
  • [Presentation] Functional analysis of cell wall-anchored nuclease from Streptococcus sanguinis.2013

    • Author(s)
      森田知里,住岡龍一,中田匡宣, 岡橋暢夫,本多真理子,住友倫子,川端重忠.
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ,千葉市, 千葉県
    • Related Report
      2012 Research-status Report
  • [Presentation] Streptococcus sanguinis induces foam cell formation and cell death of macrophages.2013

    • Author(s)
      岡橋暢夫,沖永敏則,桜井敦朗, 寺尾豊,中田匡宣,川端重忠, 西原達治.
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ,千葉市, 千葉県
    • Related Report
      2012 Research-status Report
  • [Presentation] 8-Nitro-cGMP exerts anti-bacterial effect through inactivation of bacterial GAPDH2013

    • Author(s)
      Minkyung Jung,小野勝彦, 岡本竜哉,井田知章,藤井重元, 居原秀,澤智裕,川端重忠, 熊谷嘉人,赤池孝章.
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ,千葉市, 千葉県
    • Related Report
      2012 Research-status Report
  • [Presentation] Group A streptococcal cysteine protease cleaves epithelial junctions and contributes to bacterial translocation2012

    • Author(s)
      Sumitomo T, Nakata M, Higashino M, Terao Y, and Kawabata S
    • Organizer
      The 11th Korea-Japan International Symposium on Microbiology 2012
    • Place of Presentation
      Buyeo Lotte Resort, Buyeo, Korea
    • Related Report
      2013 Final Research Report
  • [Presentation] Assembly mechanism of T6 pili in serotype M6 Streptococcus pyogenes2012

    • Author(s)
      中田匡宣,住友倫子,東野美晴,岡橋暢夫,浜田茂幸,寺尾豊,川端重忠
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎市・長崎ブリックホール
    • Related Report
      2013 Final Research Report
  • [Presentation] Group A streptococcal cysteine protease cleaves epithelial junctions and contributes to bacterial translocation.2012

    • Author(s)
      Sumitomo T, Nakata M, Higashino M, Terao Y, and Kawabata S.
    • Organizer
      The 11th Korea-Japan International Symposium on Microbiology
    • Place of Presentation
      Buyeo, Korea
    • Related Report
      2012 Research-status Report
  • [Presentation] Poor oral condition promotes harboring of salivary pneumococci in elderly.2012

    • Author(s)
      Ogawa T, Ikebe K, Kagawa R, Honda M, Terao Y, Kawabata S, and Maeda Y.
    • Organizer
      90th General Session & Exhibition of the International Association for Dental Research
    • Place of Presentation
      Iguazu Falls, Brazil
    • Related Report
      2012 Research-status Report
  • [Presentation] Assembly Mechanism of T6 Pili in Serotype M6 Streptococcus pyogenes2012

    • Author(s)
      Nakata M
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎ブリックホール(長崎市)
    • Related Report
      2011 Research-status Report
  • [Presentation] A群レンサ球菌の分泌型システインプロテアーゼであるSpeBは上皮細胞間接着分子を分解する2011

    • Author(s)
      住友倫子,中田匡宣,寺尾豊,川端重忠
    • Organizer
      第53回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岐阜市・長良川国際会議場
    • Related Report
      2013 Final Research Report
  • [Presentation] Streptococcal pyrogenic exotoxin B contributes to cleavage of epithelial junctions2011

    • Author(s)
      Sumitomo T, Nakata M, Higashino M, Terao Y, and Kawabata S
    • Organizer
      XVIII Lancefield International Symposium
    • Place of Presentation
      Hotel Hilton Villa Igiea Palermo, Palermo, Italy
    • Related Report
      2013 Final Research Report
  • [Presentation] T6線毛の形成機構とバイオフィルム形成への関与2011

    • Author(s)
      中田匡宣,木村敬次Richard,住友倫子,寺尾豊,川端重忠
    • Organizer
      第20回Lancefieldレンサ球菌研究会
    • Place of Presentation
      名古屋市・愛知学院大学薬学部・大講義室
    • Related Report
      2013 Final Research Report
  • [Presentation] A群レンサ球菌システインプロテアーゼによる上皮細胞間接着分子の分解2011

    • Author(s)
      東野美晴
    • Organizer
      第64回日本細菌学会関西支部総会
    • Place of Presentation
      大阪府立大学中百舌鳥キャンパス 学術交流会館(C1 棟)多目的ホール(大阪府)
    • Related Report
      2011 Research-status Report
  • [Presentation] A群レンサ球菌の分泌型システインプロテアーゼであるSpeBは上皮細胞間接着分子を分解する2011

    • Author(s)
      住友倫子
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      長良川国際会議場(岐阜市)
    • Related Report
      2011 Research-status Report
  • [Presentation] Streptococcal pyrogenic exotoxin B contributes to cleavage of epithelial junctions2011

    • Author(s)
      Sumitomo T
    • Organizer
      XVIII Lancefield International Symposium
    • Place of Presentation
      Hilton Villa Igiea Palermo (Palermo, Italy)
    • Related Report
      2011 Research-status Report
  • [Presentation] Pili of oral Streptococcus sanguinis bind to salivary amylase and promote biofilm formation2011

    • Author(s)
      Okahashi N
    • Organizer
      XIII International Congress of Bacteriology and Applied Microbiology
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Related Report
      2011 Research-status Report
  • [Presentation] T6線毛の形成機構とバイオフィルム形成への関与2011

    • Author(s)
      中田匡宣
    • Organizer
      第20回Lancefieldレンサ球菌研究会
    • Place of Presentation
      愛知学院大学薬学部 大講義室(名古屋市)
    • Related Report
      2011 Research-status Report
  • [Presentation] Streptococcus sanguinisが産生するヌクレアーゼの機能解析.

    • Author(s)
      森田知里,住岡龍一,中田匡宣,岡橋暢夫,住友倫子,川端重忠.
    • Organizer
      第66回日本細菌学会関西支部総会
    • Place of Presentation
      大阪府吹田市・大阪大学 微生物病研究所 谷口記念講堂
    • Related Report
      2013 Annual Research Report
  • [Presentation] Mode of expression and assembly mechanism of Group A Streptococcal pili.

    • Author(s)
      Nakata M, Kawabata S.
    • Organizer
      The 12th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji Yumebutai International Conference Center, Awaji, Hyogo, Japan
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Assembly mechanism of T6 pili and its involvement in biofilm formation.

    • Author(s)
      Nakata M, Sumitomo T, and Kawabata S.
    • Organizer
      GAS Infections 2013
    • Place of Presentation
      Roma, Italy
    • Related Report
      2012 Research-status Report
  • [Presentation] Streptococcus pyogenesのシステインプロテアーゼSpeBが補体免疫機構に及ぼす影響.

    • Author(s)
      本多真理子,寺尾豊,住友倫子, 中田匡宣,川端重忠.
    • Organizer
      第65回日本細菌学会関西支部総会
    • Place of Presentation
      臨床研究情報センター, 神戸市, 兵庫県
    • Related Report
      2012 Research-status Report
  • [Presentation] A群レンサ球菌が産生するT6線毛の発現機構の解析

    • Author(s)
      川端重忠、寺尾豊、中田匡宣、 住友倫子.
    • Organizer
      平成24年度近畿腸管微生物研究会
    • Place of Presentation
      千里ライフサイエンスセンター, 吹田市, 大阪府
    • Related Report
      2012 Research-status Report
  • [Presentation] Streptococcus pyogenesのシステインプロテアーゼSpeBによる補体免疫回避機構の解析.

    • Author(s)
      本多真理子,橋本栄,寺尾豊, 川端重忠.
    • Organizer
      第21回Lancefieldレンサ球菌研究会
    • Place of Presentation
      大阪大学,吹田市,大阪府
    • Related Report
      2012 Research-status Report
  • [Presentation] T6線毛バイオフィルム形成と菌体凝集への関与.

    • Author(s)
      森田知里,中田匡宣,木村敬次Richard,住友倫子,寺尾豊, 川端重忠.
    • Organizer
      第21回Lancefieldレンサ球菌研究会
    • Place of Presentation
      大阪大学,吹田市,大阪府
    • Related Report
      2012 Research-status Report
  • [Book] 序-注目される劇症型細菌感染症の現状と理解-.特集1「いわゆるヒト喰いバクテリアと劇症型感染症」.医薬ジャーナル社化学療法の領域2013

    • Author(s)
      川端重忠
    • Related Report
      2013 Final Research Report
  • [Book] 劇症型溶血性レンサ球菌感染症の発症に寄与する細菌因子.特集1「いわゆるヒト喰いバクテリアと劇症型感染症」.化学療法の領域2013

    • Author(s)
      住友倫子,川端重忠
    • Related Report
      2013 Final Research Report
  • [Book] 病原性レンサ球菌の二成分制御系シグナル伝達機構.特集「細菌の病原遺伝子の発現調節機構」.化学療法の領域2013

    • Author(s)
      中田匡宣,川端重忠
    • Related Report
      2013 Final Research Report
  • [Book] 病原性レンサ球菌の二成分制御系シグナル伝達機構.特集「細菌の病原遺伝子の発現調節機構」.化学療法の領域. 29 (1)2013

    • Author(s)
      中田匡宣,川端重忠.
    • Total Pages
      9
    • Publisher
      医薬ジャーナル社
    • Related Report
      2013 Annual Research Report
  • [Book] 病原性レンサ球菌の二成分制御系シグナル伝達機構.化学療法の領域.29(1)2013

    • Author(s)
      中田匡宣,川端重忠.
    • Total Pages
      9
    • Publisher
      医薬ジャーナル社
    • Related Report
      2012 Research-status Report
  • [Remarks] ホームページ

    • URL

      http://web.dent.osaka-u.ac.jp/~mcrbio/

    • Related Report
      2013 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi