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Characterization of the Porphyromonas gingivalis conjugative transposon CTnPg1: the gene transfer among oral bacteria and CTnPg1-like family CTns.

Research Project

Project/Area Number 23592704
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Morphological basic dentistry
Research InstitutionNagasaki University

Principal Investigator

NAITO Mariko  長崎大学, 医歯(薬)学総合研究科, 准教授 (20244072)

Co-Investigator(Renkei-kenkyūsha) SHOJI Mikio  長崎大学, 医歯薬学総合研究科, 助教 (10336175)
SATO Keiko  長崎大学, 医歯薬学総合研究科, 助教 (70410579)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords口腔細菌学 / 遺伝子転移 / ゲノム解析 / 転移性因子 / ゲノム / CTn / 口腔細菌 / 転移性遺伝子 / 歯周病 / CTn
Research Abstract

Conjugative transposon (CTn), CTnPg1 was one of mobile elements that were defined from Porphyromonas gingivalis. CTnPg1 can transfer among live bacteria not by transformation and transduction. CTnPg1-like CTns were found in anaerobic bacteria that composed biofilms in human oral and intestines. These result suggested that CTnPg1 and CTnPg1-like CTns are widely distributed and actively transfered among oral and intestinal bacteria.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (16 results)

All 2014 2013 2012 2011

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (15 results) (of which Invited: 1 results)

  • [Journal Article] Characterisation of the Porphyromonas gingivalis conjugative transposon CTnPg1 : determination of the integration site and the genes essential for conjugal transfer2011

    • Author(s)
      M.Naito, et al
    • Journal Title

      Microbiology

      Volume: 157 Issue: 7 Pages: 2022-2032

    • DOI

      10.1099/mic.0.047803-0

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Presentation] The impact of genomics on research in periodontal bacteria. Kyudai Oral Bioscience2014

    • Author(s)
      内藤真理子
    • Organizer
      2014第8回九大国際シンポジウム
    • Place of Presentation
      福岡リーセントホテル(福岡市)
    • Related Report
      2013 Final Research Report
  • [Presentation] The impact of genomics on research in periodontal bacteria2014

    • Author(s)
      内藤真理子 (代表)
    • Organizer
      Kyudai Oral Bioscience 2014 第8回九大国際シンポジウム
    • Place of Presentation
      福岡リーセントホテル(福岡市)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] ゲノム解析からみえてきた歯周病細菌の新たな側面2013

    • Author(s)
      内藤真理子
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Prevotella intermediaにおける遺伝子特異的変異株作成2013

    • Author(s)
      内藤真理子(代表), 中山浩次
    • Organizer
      平成25年度 第45回 九州微生物研究会総会
    • Place of Presentation
      ホテルセントラーザ博多(福岡市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 歯周病原菌Prevotella intermedia臨床分離株OMA14の全ゲノム配列決定2013

    • Author(s)
      内藤真理子 (代表)
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ 国際会議場(千葉市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Site-directed mutagenesis in Prevotella intermedia : genetic analysis of P. intermedia Por secretion system2012

    • Author(s)
      内藤真理子
    • Organizer
      First International Conference on Porphyromonas gingivalis and Related Bacterial Species
    • Place of Presentation
      良順会館(長崎市)
    • Related Report
      2013 Final Research Report
  • [Presentation] Conjugative transposon CTnPg1のaccessory geneの解析2012

    • Author(s)
      内藤真理子(代表),佐藤啓子,雪竹英治,庄子幹郎,中山浩次
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎ブリックホール(長崎市)
    • Related Report
      2013 Final Research Report
  • [Presentation] Site-directed mutagenesis in Prevotella intermedia: genetic analysis of P. intermedia Por secretion system.2012

    • Author(s)
      Mariko Naito
    • Organizer
      First International Conference on Porphyromonas gingivalis and Related Bacterial Species.
    • Place of Presentation
      長崎大学医学部 良順会館 (長崎市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Conjugative transposon CTnPg1の類似CTn とaccessory geneの解析2012

    • Author(s)
      内藤 真理子 (代表)
    • Organizer
      第6回ゲノム微生物学会年会
    • Place of Presentation
      立教大学 (東京都)
    • Related Report
      2011 Research-status Report
  • [Presentation] Conjugative transposon CTnPg1のaccessory geneの解析2012

    • Author(s)
      内藤 真理子 (代表)
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎市 長崎ブリックホール
    • Related Report
      2011 Research-status Report
  • [Presentation] Extensive genomic rearrangement in periodontal pathogen, Porphyromonas gingivalis : implication of mobile genetic elements. XIII International Congress of Bacteriology and Applied Microbiology2011

    • Author(s)
      内藤真理子
    • Organizer
      International Union of Microbiological Societies
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Related Report
      2013 Final Research Report
  • [Presentation] Extensive genomic rearrangement in periodontal pathogen, Porphyromonas gingivalis :implication of mobile genetic elements.2011

    • Author(s)
      内藤 真理子
    • Organizer
      XIII International Congress of Bacteriology and Applied Microbiology, International Union of Microbiological Societies
    • Place of Presentation
      札幌コンベンションセンター (札幌市)
    • Related Report
      2011 Research-status Report
  • [Presentation] Conjugative transposons homologous to CTnPg12011

    • Author(s)
      内藤 真理子 (代表)
    • Organizer
      XIII International Congress of Bacteriology and Applied Microbiology, International Union of Microbiological Societies
    • Place of Presentation
      札幌コンベンションセンター (札幌市)
    • Related Report
      2011 Research-status Report
  • [Presentation] conjugative transposon CTnPg1の類似CTnの解析2011

    • Author(s)
      内藤 真理子 (代表)
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      長良川国際会議場 (岐阜市)
    • Related Report
      2011 Research-status Report
  • [Presentation] conjugative transposon CTnPg1の類似CTnの解析2011

    • Author(s)
      内藤 真理子 (代表)
    • Organizer
      第43回九州微生物研究会総会
    • Place of Presentation
      ホテルセントラーザ博多 (福岡市)
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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