Development of regenerative therapy of cementum to the gap of vertical root fracture and interdigitation to the resin
| Project/Area Number |
23592789
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
SUGAYA Tsutomu 北海道大学, 歯学研究科(研究院), 准教授 (10211301)
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| Co-Investigator(Kenkyū-buntansha) |
TENKUMO Taichi 北海道大学, 大学院歯学研究科, 専門研究員 (80451425)
NAKATSUKA Megumi 北海道大学, 大学病院, 助教 (00547648)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Keywords | ４-META/MMA-TBBレジン / 炭酸カルシウム / αＴＣＰ / 骨接触率 / 骨形成 / ハイブリッド / BMP / 骨接触 / 骨髄 / ナノハイドロキシアパタイト / 接着強さ / カルシウム溶出 / 象牙質吸収 |
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| Research Abstract |
4META/MMA-TBB resin and calcium carbonate or TCP were made composition, and elution of Ca2+ was measured. Ca2+ elution of all samples increased as the concentration becomes higher. That of beta-TCP had less than alpha-TCP and calcium carbonate. 4META/MMA-TBB resin containing alpha-TCP can facilitate direct contact between the resin and newly formed born. The hybrid layer with the bone marrow was formed on the resin surface when resin was cured in bone marrow, and the rate of bone-resin contact improved. BMP soaked collagen menbrane-nanohydroxyapatite composition was put on dentin and implanted in a femoral musle. Then a high percentage of hard tissue formation to the dentin surface was provided. 4META/MMA-TBB resin containing alpha-TCP was adhered on root surface, and BMP soaked collagen menbrane-nanohydroxyapatite composition was put on the resin. The hard tissue formation was observed on the resin.
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Report
(4 results)
Research Products
(22 results)
