Effects of desensitizing agents Analysis of dentin permeability by photochemical tracer method
| Project/Area Number |
23592792
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ISHIHATA Hiroshi 東北大学, 大学院歯学研究科, 助教 (40261523)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 知覚過敏 / 抑制材 / 象牙質透過性 / 光化学 / ルミノール / 象牙質 / 透過性 / 抑制剤 / トレーサー法 |
|---|
| Research Abstract |
The cause for regression of hypersensitivity has not yet been fully elucidated. We have established a method to measure quantitatively dentin permeability, and to analyze the time-based effect of hypersensitivity. The gradual relief of hypersensitivity with time was analyzed by morphological analysis of the dentin slices and measurement of their permeability. Crystal deposition in orifices of dentinal tubules was evident. Even small particle size crystallites not completely obturating dentinal tubules, have a major effect on reduction of permeability. The concentration of hydroxyethyl methacrylate affects the permeability of resin-based material for hypersensitivity. The structure and volume of the internal crystal varies depending on the stock solution in calcium phosphate-based material.
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Report
(4 results)
Research Products
(18 results)
