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Effects of desensitizing agents Analysis of dentin permeability by photochemical tracer method

Research Project

Project/Area Number 23592792
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionTohoku University

Principal Investigator

KANEHIRA Masafumi  東北大学, 歯学研究科(研究院), 助教 (30177539)

Co-Investigator(Kenkyū-buntansha) ISHIHATA Hiroshi  東北大学, 大学院歯学研究科, 助教 (40261523)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords知覚過敏 / 抑制材 / 象牙質透過性 / 光化学 / ルミノール / 象牙質 / 透過性 / 抑制剤 / トレーサー法
Research Abstract

The cause for regression of hypersensitivity has not yet been fully elucidated. We have established a method to measure quantitatively dentin permeability, and to analyze the time-based effect of hypersensitivity. The gradual relief of hypersensitivity with time was analyzed by morphological analysis of the dentin slices and measurement of their permeability. Crystal deposition in orifices of dentinal tubules was evident. Even small particle size crystallites not completely obturating dentinal tubules, have a major effect on reduction of permeability. The concentration of hydroxyethyl methacrylate affects the permeability of resin-based material for hypersensitivity. The structure and volume of the internal crystal varies depending on the stock solution in calcium phosphate-based material.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (18 results)

All 2014 2013 2012 2011 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (11 results)

  • [Journal Article] Effects of applying glutaraldehyde-containing desensitizer formulations on reducing dentin permeability2012

    • Author(s)
      Hiroshi Ishihata, Masafumi Kanehira, Werner J. Finger, Hidetoshi Shimauchi, Masashi Komatsu
    • Journal Title

      Journal of Dental Sciences

      Volume: 7 Issue: 2 Pages: 105-110

    • DOI

      10.1016/j.jds.2012.03.005

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of two topical desensitizing agents and placebo on dentin hypersensitivity2012

    • Author(s)
      JUGAL VORA,WERNER J. FINGER,MASAFUMI KANEHIRA,他3名
    • Journal Title

      American Journal of Dentistry

      Volume: 25(2) Pages: 293-298

    • URL

      http://www.amjdent.com/

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of two topical desensitizing agents and placebo on dentin hypersensitivity2012

    • Author(s)
      JUGAL VORA,DEEPAK MEHTA,NAGANATH MEENA,GALAGALI SUSHMA,WERNER J. FINGER,MASAFUMI KANEHIRA
    • Journal Title

      American Journal of Dentistry

      Volume: 25 Pages: 293-298

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of glutaraldehyde, HEMA, and Gluma Desensitizer on in vitro dentin permeability2011

    • Author(s)
      Hiroshi Ishihata, Masafumi Kanehira, Werner J. Finger, Hidetoshi Shimauchi, Masashi Komatsu
    • Journal Title

      International Journal of Contemporary Dentistry

      Volume: 2(1) Pages: 3-8

    • URL

      http://edentj.com/index.php/ijcd/index

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] In vitro dentin permeability after application of Gluma® desensitizer as aqueous solution or aqueous fumed silica dispersion2011

    • Author(s)
      Hiroshi Ishihata, Werner J. Finger, Masafumi Kanehira, Hidetoshi Shimauchi, Masashi Komatsu
    • Journal Title

      J Appl Oral Sci

      Volume: 19(2) Pages: 147-153

    • URL

      http://www.scielo.br/scielo.php?script=sci_serial&pid=1678-7757

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] In vitro dentin permeability after application of Gluma® desensitizer as aqueous solution or aqueous fumed silica dispersion2011

    • Author(s)
      Hiroshi IshihataI, Werner J. Finger, Masafumi Kanehira, Hidetoshi Shimauchi, Masashi Komatsu
    • Journal Title

      Journal of Applied Oral Science

      Volume: 19 Issue: 2 Pages: 147-153

    • DOI

      10.1590/s1678-77572011000200011

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Comparative evaluation of mechanical characteristics of nanofiller containing resin composites2011

    • Author(s)
      HIDEKAZU TAKAHASHI, WERNER J. FINGER, TATSUO ENDO, MASAFUMI KANEHIRA, NATTHAVOOT OOTTATHAPE, MASASHI KOMATSU, MARKUS BALKENHO
    • Journal Title

      American Journal of Dentistry

      Volume: 24 Pages: 264-270

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] In vitro evaluation of dentin permeability after application of a calcium-phosphate desensitizer2014

    • Author(s)
      Kanehira M, Ishihata H, Finger WJ, Masahiro Saito
    • Organizer
      Innovative Research for Biosis-Abiosis Intelligent Interface Symposium
    • Place of Presentation
      仙台
    • Related Report
      2013 Final Research Report
  • [Presentation] In vitro evaluation of dentin permeability after application of a calcium-phosphate desensitizer2014

    • Author(s)
      Kanehira M, Ishihata H, Finger WJ, Masahiro Saito
    • Organizer
      Innovative Research for Biosis-Abiosis Intelligent Interface Symposium
    • Place of Presentation
      Katahira Sakura Hall(仙台)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Determination of the velocity of fluid flow in dentinal tubules using a photochemical detector2013

    • Author(s)
      Boreak N.M., Ishihata H., Kanehira M., Finger W.J., Shimauchi H., Komatsu M
    • Organizer
      NIH Tohoku University JSPS Symposium
    • Place of Presentation
      仙台
    • Year and Date
      2013-05-09
    • Related Report
      2013 Final Research Report
  • [Presentation] 知覚過敏抑制材の象牙質透過性に及ぼす影響2013

    • Author(s)
      山口純世、兼平正史、石幡浩志、FINGER W.J
    • Organizer
      本歯科保存学会2013年度春季学術大会
    • Place of Presentation
      博多
    • Related Report
      2013 Final Research Report
  • [Presentation] Permeability of experimental self-etch adhesives with different content of HEMA2013

    • Author(s)
      Masafumi KANEHIRA, Hiroshi ISHIHATA, Nezar M. BOREAK, Werner J. FINGER, Hidetoshi SHIMAUCHI
    • Organizer
      The 92nd General Session & Exhibition of the the International Association for Dental Research
    • Place of Presentation
      シアトル(USA)
    • Related Report
      2013 Final Research Report
  • [Presentation] Determination of the velocity of fluid flow in dentinal tubules using a photochemical detector2013

    • Author(s)
      Boreak N.M., Ishihata H., Kanehira M., Finger W.J., Shimauchi H., Komatsu M.
    • Organizer
      NIH Tohoku University JSPS Symposium
    • Place of Presentation
      艮陵会館記念ホール(仙台)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 知覚過敏抑制材の象牙質透過性に及ぼす影響2013

    • Author(s)
      山口純世、兼平正史、石幡浩志、FINGER W.J.
    • Organizer
      日本歯科保存学会2013年度春季学術大会
    • Place of Presentation
      福岡国際会議場(博多)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Permeability of experimental self-etch adhesives with different content of HEMA2013

    • Author(s)
      Masafumi KANEHIRA1, Hiroshi ISHIHATA, Nezar M. BOREAK, Werner J. FINGER, Hidetoshi SHIMAUCHI
    • Organizer
      The 92nd General Session & Exhibition of the the International Association for Dental Research
    • Place of Presentation
      ワシントン州立コンベンションセンター(シアトル、アメリカ)
    • Related Report
      2012 Research-status Report
  • [Presentation] Effect of smear produced with a resin fiber bur on in vitro permeability of human dentin2012

    • Author(s)
      石幡浩志、兼平正史、ボレイクネザール、FINGER WJ、島内英俊、小松正志
    • Organizer
      日本歯科保存学会2012年度春季学術大会
    • Place of Presentation
      那覇
    • Related Report
      2013 Final Research Report
  • [Presentation] Effect of smear produced with a resin fiber bur on in vitro permeability of human dentin2012

    • Author(s)
      石幡浩志、兼平正史、ボレイク ネザール、FINGER WJ、島内英俊、小松正志
    • Organizer
      日本歯科保存学会2012年度春季学術大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄)
    • Related Report
      2012 Research-status Report
  • [Presentation] Depth of Cure of Light-activated Nanofiller Containing Resin Composites

    • Author(s)
      KANEHIRA M, HOSHINO T, UTTERODT A, FINGER WJ, KOMATSU M
    • Organizer
      International Dental Materials Congress 2011
    • Place of Presentation
      ソウル 大韓民国
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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