| Project/Area Number |
23592793
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
NOJI Miyoko 東北大学, 歯学研究科(研究院), 大学院非常勤講師 (70431583)
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| Co-Investigator(Kenkyū-buntansha) |
SASAKI Keiichi 東北大学, 歯学研究科(研究院), 教授 (30178644)
AKATSUKA Ryo 東北大学, 歯学研究科(研究院), 助教 (10586514)
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| Co-Investigator(Renkei-kenkyūsha) |
SUZUKI Osamu 東北大学, 歯学研究科(研究院), 教授 (60374948)
KURIYAGAWA Tsunemoto 東北大学, 工学研究科(研究院), 教授 (90170092)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | パウダージェットデポジション / ハイドロキシアパタイト / 前臨床試験 / 変色歯 / 探索的臨床研究 / インターフェイス / サーマルサイクル / 象牙質 |
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| Research Abstract |
A powder jet deposition (PJD) process can be used to create a thick hydroxyapatite (HA) film on the surface of a human tooth. In the experiment using dentin, class V cavities were prepared on the buccal surfaces of the teeth of beagle dogs and filled with (1) resin composite on the HA film, (2) zinc oxide-eugenol cement as a negative control group, or (3) zinc phosphate cement as a positive control group. In the experiment using enamel, the enamel was polished and coated with (1) the HA films, (2) resin sealants as one negative control group, and (3) glass ionomer cement as the other negative control group. No severe inflammatory responses were observed in all specimens applied by PJD, showing even milder response than that of specimens used as negative control. The bacteria were not identified in the pulp space or dentinal tubules in any postoperative periods.
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