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The study of the gene distribution and the role in hard tissue formation of amelogenin

Research Project

Project/Area Number 23592807
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionShowa University

Principal Investigator

YAMADA Yoshishige  昭和大学, 歯学部, 講師 (40360127)

Co-Investigator(Kenkyū-buntansha) MASUDA Yoshiko  昭和大学, 歯学部, 准教 (10297038)
KAWANAKA Takao  昭和大学, 歯学部, 助教 (10365702)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywordsアメロジェニン / マウス胎仔 / エクソン / In situ hybridization法 / in situ hybridization法 / パラフィン切片 / in situ PCR / in situ LAMP / in situ hybridizatiom / 胎生マウス / マウス胎児 / PCR法 / in situ PCR法 / LAMP法
Research Abstract

According to the results of in situ hybridization, amelogenin gene expression was observed several non tooth related tissue such as brain, kidney, eye and bone related tissues.
The amelogenin gene expression in these tissues, were a significant small amount of gene expression compared with gene expression in ameloblast of incisor. The tendency of the expression level of the amelogenin gene in the tissue they become strong in the late gestation than early fetal period has been confirmed.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (1 results)

All 2013

All Presentation (1 results)

  • [Presentation] 胎生マウスにおけるアメロジェニン遺伝子発現様式の検討2013

    • Author(s)
      山田嘉重
    • Organizer
      第14回エナメル質比較発生学懇話会
    • Place of Presentation
      新潟
    • Related Report
      2013 Annual Research Report 2013 Final Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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