Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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Research Abstract |
As a preliminary experiment, we investigated the effect of ultrasonic treatment for hydroxyapatite ceramics to the cell adhesion. Due to ultrasonic treatment at the surface of hydroxyapatite ceramics, a plenty of micro pores and micro cracks were observed and the increasing cell numbers raised the ability of cell adhesion to the ceramics. Osteoblastic cell culturing under the biomimetic condition caused cells extended the process three dimensionally on collagen gel. And Cells increased osteocalcin expression against mechanical stress by hydroxyl apatite block.
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