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Application of effect of low-magnitude and high-frequency loading on peri-implant bone to the implant

Research Project

Project/Area Number 23592835
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthetic dentistry
Research InstitutionTohoku University

Principal Investigator

OGAWA Toru  東北大学, 大学病院, 講師 (50372321)

Co-Investigator(Kenkyū-buntansha) SASAKI Keiichi  東北大学, 大学院歯学研究科, 教授 (30178644)
IKEDA Kiyohiro  東北大学, 工学(系)研究科, 教授 (50168126)
YAMAKAWA Yuki  東北大学, 工学(系)研究科, 准教授 (80324010)
SHIGEMITSU Ryuji  東北大学, 大学病院, 助教 (00508921)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywordsインプラント / 振動刺激 / 高周波 / オッセオインテグレーション / 有限要素 / メカノバイオロジー / 有限要素解析
Research Abstract

This study aimed to examine the influence of various loading on dynamic changes of bone-metabolism around the implant using a super-high resolution [18F]NaF-PET in rat tibiae. Adult male Wistar rats installed experimental implant on the tibia were used in this study. Increase of bone-metabolism was observed until 7 days after implantation surgery and then gradually decreased. Differences in bone-metabolism between immediate loading and no-loading group were found. This suggests loading affects bone-metabolism around the implant. Also

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (12 results)

All 2014 2013 2012 2011

All Journal Article (5 results) (of which Peer Reviewed: 3 results) Presentation (7 results)

  • [Journal Article] Stimulation of titanium implant osseointegration through high frequency vibration loading is enhanced when applied at high acceleration2014

    • Author(s)
      Ogawa T, Vandamme K, Zhang X, Naert I, Possemiers T, Chaudhari A, Sasaki K, Duyck J.
    • Journal Title

      Calcif Tissue Int

      Volume: (in press)

    • Related Report
      2013 Final Research Report
  • [Journal Article] Stimulation of titanium implant osseointegration through high frequency vibration loading is enhanced when applied at high acceleration.2014

    • Author(s)
      Ogawa T, Vandamme K, Zhang X, Naert I, Possemiers T, Chaudhari A, Sasaki K, Duyck J.
    • Journal Title

      Calcif Tissue Int.

      Volume: 未定

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of immediate and early loading on bone metabolic activity around dental implants in rat tibiae2013

    • Author(s)
      Yamamoto M, Ogawa T, Yokoyama M, Koyama S, Sasaki K.
    • Journal Title

      Clin Oral Implants Res

      Volume: (印刷中) Issue: 9 Pages: 1084-1090

    • DOI

      10.1111/clr.12218

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Stress distribution in the peri-implant bone with splinted and non-splinted implants by in vivo loading data-based finite element analysis2013

    • Author(s)
      Shigemitsu R, Ogawa T, Matsumoto T, Yoda N, Gunji Y, Yamakawa Y, Ikeda K, Sasaki K.
    • Journal Title

      Odontology

      Volume: 101 Pages: 222-6

    • NAID

      10031194894

    • Related Report
      2013 Final Research Report
  • [Journal Article] Stress distribution in the peri-implant bone with splinted and non-splinted implants by in vivo loading data-based finite element analysis.2012

    • Author(s)
      Shigemitsu R, Ogawa T, Matsumoto T, Yoda N, Gunji Y, Yamakawa Y, Ikeda K, Sasaki K
    • Journal Title

      Odontology

      Volume: in press Issue: 2 Pages: 222-226

    • DOI

      10.1007/s10266-012-0077-y

    • NAID

      10031194894

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] Effect of low-magnitude and high-frequency loading on bone defect healing2013

    • Author(s)
      Kanda Y, Ogawa T, Vandamme K, Shibamoto A,Zhang X, Naert I, Sasaki K, Duyck J.
    • Organizer
      91th The International Association for Dental Research (IADR)
    • Place of Presentation
      Seattle, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] [18F]NaF-PET Image Analyses of Peri-implant bone metabolism elicited Loading2013

    • Author(s)
      Matsuo Y, Yamamoto M, Ogawa T, Yokoyama M, Sasaki K.
    • Organizer
      7th East Asian Consortium on Biomedical Engineering
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2013 Final Research Report
  • [Presentation] [18F]NaF-PET Image Analyses of Peri-implant Bone Metabolism Elicited by Loading2013

    • Author(s)
      Yutaka Matsuo, Miou Yamamoto, Toru Ogawa, Masayoshi Yokoyama, Keiichi Sasaki
    • Organizer
      7th East Asian Consortium on Biomedical Engineering
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effect of low-magnitude and high-frequency loading on bone defect healing2013

    • Author(s)
      Kanda Y, Ogawa T, Vandamme K, Shibamoto A, Zhang X, Naert I, Sasaki K, Duyck J
    • Organizer
      91th The International Association for Dental Research (IADR)
    • Place of Presentation
      Seattle, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Evaluation of Peri-Implant Bone Metabolism with High-resolution-NaF-PET during Mechanical Loading2012

    • Author(s)
      Matsuo Y, Yamamoto M, Ogawa T, Yokoyama M, Sasaki K.
    • Organizer
      The 60th Annual Meeting of Japanese Association for Dental Research
    • Place of Presentation
      Niigata, Japan
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] 低強度・高周波振動刺激によるインプラント周囲骨の骨形成活性化に関する研究2011

    • Author(s)
      小川徹, 張暁磊, Naert I, 佐々木啓一, Duyck J
    • Organizer
      第120回日本補綴歯科学会学術大会
    • Place of Presentation
      広島
    • Related Report
      2011 Research-status Report
  • [Presentation] 固定性インプラント補綴における支台インプラント本数・植立位置とインプラント荷重との関連2011

    • Author(s)
      小針啓司, 依田信裕, 郡司良律, 川田哲男, 小川徹, 佐々木啓一
    • Organizer
      第46回日本顎口腔機能学会学術大会
    • Place of Presentation
      仙台
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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