| Project/Area Number |
23592853
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | The University of Tokushima |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ICHIKAWA Tetsuo 徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授 (90193432)
NAGAO Kan 徳島大学, 大学院ヘルスバイオサイエンス研究部, 准教授 (30227988)
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| Co-Investigator(Renkei-kenkyūsha) |
HIROTA Katsuhiko 徳島大学, 大学院ヘルスバイオサイエンス研究部, 准教授 (60199130)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 高齢者 / 誤嚥性肺炎 / 口腔ケア / 口腔刺激 / 免疫 / 慢性期 / 光トポグラフィー / 効果の遅延 / miRNA |
|---|
| Research Abstract |
The purpose of this study is to clarify why the efficacies of oral care is delayed in the chronic phase, to re-recognize the significance of oral care, to explore effective oral care methods. The following research has been done: literature review, measurements of the cerebral blood flow in the prefrontal cortex using a light topography (NIRS), the effect of oral stimulation on the immune function and behavior patterns (Induction of anxious feeling) in mice, and the development of simple oral care evaluation method. As a result, it could be found to impact on the activity of brain function by the stimulation into the oral cavity compared to that into the other site, but little effect on immune function was found. It is suggested that the delay, conversely the effect, would be multifactorially caused.
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