Project/Area Number |
23592857
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Prosthetic dentistry
|
Research Institution | Kyushu University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
MAKIHIRA Seicho 九州大学, 歯学研究院, 准教授 (80304450)
MOROI Ryoji 九州大学, 大学病院, 助教 (70325471)
TERADA Yoshihiro 九州大学, 歯学研究院, 教授 (30038898)
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
Keywords | 唾液 / 抗菌性蛋白質 / 抗菌歯科材料 / ラクトフェリン / 抗菌性 / 細胞毒性 / 抗菌材料 |
Research Abstract |
In the super-aged society, it is often the case thatresults in systemic disease by the bacterials with the tissue conditioner and denture. Many antimicrobial dental materials including antimicrobial agents have been developed in recent years. However, there is a possibility that they are harmful to the human body such as allergic. So, we want to develop a dental materials, such as increasing the local concentration of the antibacterial protein contained in the human saliva. In other words, this research was conducted for the purpose of development of antibacterial dental materials that do not contain any antimicrobial agents. In the present study, we apply this method to tissue conditioner frequently used in denture and develope the tissue conditioner with high biocompatibility antibacterial.
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